- Our Best Picks
- 1. Best Overall Digestive Enzyme: Physician’s CHOICE Digestive Enzymes (60 Capsules)
- 2. Best High-Potency Formula: Double Wood Digestive Enzymes 800mg (90 Capsules)
- 3. Best Vegan-Friendly Enzymes: Naturenetics DigestWise Digestive Enzymes (90 Capsules)
- 4. Best Enzyme-Probiotic Combo for Daily Gut Health: GoBiotix Digestive Enzymes (60 Capsules)
- 5. Best Value Digestive Enzymes: Nutricost Digestive Enzymes 620mg (120 Capsules)
- 6. Best Plant-Based Formula: Sports Research Digestive Enzymes with Probiotics & Ginger (90 Capsules)
- 7. Best for Gluten Sensitivity: MaryRuth Organics Gluten Enzymes (60 Capsules)
- Benefits of Taking Digestive Enzyme Supplement
- The Dosage Instructions for Digestive Enzymes Supplements
- The Side-Effects and Risks of Digestive Enzymes Supplements
- Frequently Asked Questions (FAQs)
- The Final Note
Digestive enzymes, as the name suggests, are needed by the body for the digestion of nutrients obtained from food sources.
They begin to work as soon as the food enters the mouth. Saliva has digestive enzymes that start the breakdown process of nutrients. The pancreas, gallbladder, and liver also release these enzymes.
At times the body is unable to produce sufficient digestive enzymes. This leads to conditions like the midriff bloating, flatulence, and loose stool (1).
Supplementation with these enzymes helps bring relief from such conditions. A prescribed dose deals with long term digestive disorders like IBS (IBS-Irritable Bowel Syndrome), which affects the large intestine (2).
Here are the 7 best digestive enzymes in various categories such as the budget ones to the best vegan alternatives, as well as, the best digestive enzymes for those who have lactose intolerance.
Our Best Picks
1. Best Overall Digestive Enzyme: Physician’s CHOICE Digestive Enzymes (60 Capsules)
- Why? Combines a dual-action formula with 10 broad-spectrum enzymes, organic prebiotics, and 1 billion CFU probiotics. Doctor-formulated, vegan-friendly, and clinically reviewed for real digestive relief.
- Key Benefits: Relieves bloating and discomfort, supports gut microbiome, enhances nutrient absorption.
- Best for: Individuals looking for comprehensive gut support with both enzymes and probiotics.
2. Best High-Potency Formula: Double Wood Digestive Enzymes 800mg (90 Capsules)
- Why? Delivers 800 mg of 10 essential enzymes in one of the most concentrated formulas. Gluten-free, vegan, and made in the USA with third-party testing.
- Key Benefits: Supports digestion of carbs, proteins, fats, and lactose with maximum potency.
- Best for: Users who want a pure, strong, no-frills digestive enzyme blend.
3. Best Vegan-Friendly Enzymes: Naturenetics DigestWise Digestive Enzymes (90 Capsules)
- Why? Offers 10 plant-based enzymes that are non-GMO, keto-friendly, and suitable for vegan diets. Designed to ease gas, bloating, and irregularity.
- Key Benefits: Promotes digestion of hard-to-digest foods, enhances bowel regularity.
- Best for: Those with sensitive stomachs or plant-based diets needing gentle support.
4. Best Enzyme-Probiotic Combo for Daily Gut Health: GoBiotix Digestive Enzymes (60 Capsules)
- Why? Combines digestive enzymes with probiotics and prebiotics for total gut health. Plant-based and formulated to support gluten and lactose digestion.
- Key Benefits: Reduces bloating, improves nutrient absorption, supports microbiome balance.
- Best for: Daily gut maintenance and food intolerance relief in both men and women.
5. Best Value Digestive Enzymes: Nutricost Digestive Enzymes 620mg (120 Capsules)
- Why? Provides a complete enzyme blend at an affordable price. Each bottle offers a generous 120-capsule supply and is made in a GMP-compliant facility.
- Key Benefits: Supports protein, fat, and carb digestion; improves overall digestive efficiency.
- Best for: Budget-conscious users wanting a long-lasting enzyme supply.
6. Best Plant-Based Formula: Sports Research Digestive Enzymes with Probiotics & Ginger (90 Capsules)
- Why? Includes 15 vegan enzymes, 1 billion CFU probiotics, and soothing ginger for enhanced digestion. Non-GMO verified and third-party tested.
- Key Benefits: Helps digest dairy, proteins, sugar, and carbs; reduces bloating naturally.
- Best for: Users seeking plant-based, gentle enzyme support with added probiotic balance.
7. Best for Gluten Sensitivity: MaryRuth Organics Gluten Enzymes (60 Capsules)
- Why? Specifically formulated to assist gluten breakdown with a unique blend of enzymes including protease, cellulase, and lactase. Vegan and allergen-free.
- Key Benefits: Supports gluten digestion, reduces gas and bloating after gluten exposure.
- Best for: Individuals with mild gluten sensitivity (not suitable for celiac disease).
| Rank | Product | Form | Price per Count | Highlight | Key Benefits | Best For |
|---|---|---|---|---|---|---|
| 1️⃣ | Physician’s CHOICE Digestive Enzymes (60ct) | Capsule | ~$0.40 | Best Overall Digestive Enzyme | Relieves bloating and gas, supports nutrient absorption and gut health | Users seeking a balanced enzyme with prebiotics + probiotics |
| 2️⃣ | Double Wood Digestive Enzymes 800mg (90ct) | Capsule | ~$0.22 | Best High-Potency Blend | Supports digestion of carbs, protein, fats, and lactose | Those needing a strong, simple enzyme-only formula |
| 3️⃣ | Naturenetics DigestWise (90ct) | Capsule | ~$0.34 | Best for Sensitive Stomachs | Helps with bloating, gas, and constipation | Individuals seeking clean-label enzymes with no allergens |
| 4️⃣ | GoBiotix Digestive Enzymes with Probiotics (60ct) | Capsule | ~$0.42 | Best for Gut Flora Balance | Supports digestion and microbiome health | People looking for both enzymes and probiotics in one formula |
| 5️⃣ | Nutricost Digestive Enzymes 620mg (120ct) | Capsule | ~$0.15 | Best Value Digestive Enzymes | Aids breakdown of proteins, carbs, dairy | Budget-conscious users needing basic enzyme support |
| 6️⃣ | Sports Research Digestive Enzymes with Probiotics & Ginger (90ct) | Capsule | ~$0.28 | Best with Herbal Support | Supports digestion, gut balance, reduces discomfort | Those wanting enzymes with ginger and probiotics |
| 7️⃣ | MaryRuth Organics Gluten Enzymes (60ct) | Capsule | ~$0.30 | Best for Gluten Sensitivity | Aids gluten digestion, reduces bloating and gas | Gluten-sensitive individuals needing specific enzyme support |
1. Best Overall Digestive Enzyme: Physician’s CHOICE Digestive Enzymes (60 Capsules)

Price: Price not available
Physician’s Choice Digestive Enzymes is a vegan-friendly supplement designed to ease mealtime discomfort by combining a powerful 16-enzyme blend with prebiotics and soil-based probiotics. Developed with doctors and backed by third-party testing, it aims to reduce bloating, gas, and irregularity in both everyday and high-stress digestive scenarios.
Key Benefits
- Supports the breakdown of proteins, carbs, fats, dairy, legumes, and fiber
- Combines digestive enzymes with prebiotics and SBO probiotics
- Helps improve regularity and gut health
- May reduce bloating and improve post-meal comfort
- No refrigeration needed and free from major allergens
Main Ingredients
- Digestive Enzyme Blend (85 mg): Includes bromelain, amylase, protease, papain, cellulase, lipase, lactase, and more
- Herbal Blend (150 mg): Organic peppermint leaf and ginger root to soothe the stomach
- Prebiotic and Probiotic Blend (159 mg): Includes inulin, organic acacia fiber, and 3 soil-based probiotic strains (Bacillus subtilis, Bacillus coagulans, Bacillus clausii)
Pros
- Comprehensive enzyme coverage for all food groups
- Includes natural herbs to calm the digestive tract
- Features 3 soil-based probiotics that survive stomach acid
- Vegan and free from dairy, soy, gluten, eggs, nuts, GMOs, and artificial additives
- 3rd-party tested for purity and potency
Cons
- Some users report herbal aftertaste
- A few sensitive individuals experienced stomach aches or headaches
- May not be ideal for those with known herbal sensitivities
Customer Feedback:
- Effectiveness:
Many users reported near-instant relief from bloating and improved regularity. Some noted they feel lighter and more comfortable after meals. - Digestion:
Frequently praised for resolving indigestion, easing upset stomachs, and promoting a flat tummy. Several customers mentioned improved energy and elimination. - Hydration & Regularity:
Users experienced more balanced hydration and smoother bowel movements. It’s often described as keeping things “running smoothly.” - Feel Good:
Customers reported feeling more comfortable, sleeping better, and having improved energy levels. It’s commonly used by those with IBS or food sensitivities. - Ease of Use:
Capsules are easy to swallow with no unpleasant aftertaste. Many customers take it before meals without any discomfort. - Prebiotics & Probiotics:
Customers appreciated the inclusion of both, calling it a reliable all-in-one solution for gut support. - Value for Money:
Opinions are mixed—many say it’s a great value, especially with Subscribe & Save discounts, while a few feel it’s slightly pricey. - Side Effects:
Some negative reviews mention stomachaches, constipation, or headaches, mostly among sensitive users. These cases appear to be in the minority.
Best Suited For
Ideal for adults dealing with regular bloating, occasional indigestion, or discomfort from diverse food types. Also suitable for vegans and those with food sensitivities looking for a non-refrigerated formula.
Usage Recommendations
Take 1 capsule before meals. For best results, stay consistent with daily use and adjust timing if needed (some users report better results when taken at night).
Summary: Physician’s Choice Digestive Enzymes offers a doctor-formulated, dual-action approach to digestive health with 16 enzymes, natural herbal support, and resilient probiotics. It’s a go-to option for those seeking complete gut support in a vegan-friendly formula.
2. Best High-Potency Formula: Double Wood Digestive Enzymes 800mg (90 Capsules)

Price: Price not available
Double Wood’s Essential Digestive Enzymes is a budget-friendly supplement offering a potent 800 mg enzyme blend per serving. With 10 of the most essential digestive enzymes—including pancreatic enzymes like amylase, lipase, and protease—it’s designed to support overall digestive health, ease discomfort, and enhance nutrient absorption.
Key Benefits
- Helps break down fats, carbs, proteins, fiber, and dairy
- Supports nutrient absorption and gut function
- Eases bloating and gas
- Promotes comfort after meals, even with complex foods
- Backed by third-party testing for purity and potency
Main Ingredients
- VitaZyme Digestive Enzyme Blend (800 mg): Includes 10 enzymes such as bromelain, lactase, amylase, lipase, papain, invertase, cellulase, maltase, glucoamylase, and protease
- Other ingredients: Gelatin capsule, microcrystalline cellulose, vegetable stearate, and silica
- Suggested Use: 2 capsules daily (with or without food)
Pros
- High-potency 800 mg formula
- Contains all key enzymes needed for full-spectrum digestion
- No fillers or unnecessary additives
- Third-party tested and made in the USA
- Outstanding value at just $0.09 per capsule
Cons
- No probiotics or prebiotics included
- Not vegan-friendly (gelatin capsule)
- May not be suitable for those with pineapple (bromelain) or papaya (papain) sensitivities
Customer Feedback:
- Effectiveness:
Many customers notice results within 24 hours. Described as a “go-to” for digestive relief, especially for those with pancreatic insufficiency or acid reflux. - Digestion:
Highly rated for easing digestive discomfort, improving regularity, and reducing bloating. A few mention relief from IBS-like symptoms. - Stomach Discomfort:
Users report gentler digestion, less abdominal pressure, and better comfort after meals. Helpful for those dealing with irritable bowel or post-meal heaviness. - Value for Money:
Universally praised for affordability. Many customers compare it favorably to $50+ prescription options and appreciate the cost-effectiveness. - Ease of Swallowing:
Capsules are noted to be tasteless, small, and easy to swallow—even for those sensitive to pill size. - Gas Content:
Most users report reduced gassiness, though a few noted increased gas likely due to sensitivity to certain enzymes. - Ease of Use:
Simple once-daily routine with no need for refrigeration or complex timing. Convenient for travel or regular daily use. - Nutrients:
Customers like that the blend aids nutrient breakdown and complements meals with protein, fats, and starches.
Best Suited For
Those seeking an affordable, no-frills enzyme formula to improve digestion and reduce bloating—especially individuals who eat heavy, protein-rich, or dairy-inclusive meals.
Usage Recommendations
Take 2 capsules once per day, either with meals or on an empty stomach. Customers report best results when taken consistently before large meals.
Summary: Double Wood’s Essential Digestive Enzymes offers a high-dose enzyme blend at an unbeatable price. It’s an ideal pick for budget-conscious users looking for real digestive relief—without added probiotics or fluff.
3. Best Vegan-Friendly Enzymes: Naturenetics DigestWise Digestive Enzymes (90 Capsules)

Price: Price not available
Naturenetics DigestWise is a plant-based digestive enzyme formula designed to support overall digestion and relieve common digestive complaints like bloating, gas, and constipation. It contains a well-rounded blend of 10 vegan enzymes and is formulated for people with sensitive stomachs or those following special diets like keto or vegan. Each capsule is made in the USA, third-party tested, and free from common allergens.
Key Benefits
- Supports digestion of proteins, fats, carbohydrates, and fiber
- Helps reduce gas, bloating, and constipation after meals
- May ease discomfort from food intolerances (e.g., lactose, gluten)
- Suitable for low-acid or sensitive stomachs
- Gentle formula with no harsh fillers or additives
Key Ingredients
Each capsule contains a proprietary blend of 10 digestive enzymes, including:
- Protease, Amylase, Lipase – for general protein, carb, and fat digestion
- Lactase – supports lactose digestion
- Cellulase, Hemicellulase – break down plant fibers
- Xylanase, Glucoamylase, Invertase, Alpha Galactosidase – help digest starches, sugars, and complex carbs
Form: Capsule
Serving Size: 1 capsule per meal (90 capsules per bottle)
Pros
- Vegan and keto-friendly formula
- Designed for sensitive stomachs and low stomach acid
- Free from gluten, soy, dairy, and GMOs
- Made in the USA in cGMP-certified facility
- Third-party tested for safety and potency
Cons
- Some users may need to take 2 capsules for larger meals
- Does not contain betaine HCl or probiotics for additional gut support
Customer Feedback:
- Value for Money: Most customers feel it’s a fair price for a gentle, well-rounded enzyme formula, especially considering it’s vegan and allergen-free.
- Effectiveness: Many report less bloating, better digestion of fibrous meals, and relief from gas and post-meal heaviness.
- Ease of Use: Capsules are small and easy to swallow. Users appreciate needing only one per meal in most cases.
- Overall Satisfaction: Customers with IBS, sensitive stomachs, or food sensitivities especially appreciate its clean formulation and gentle effectiveness.
Best Suited For
People with sensitive digestion, low stomach acid, or food intolerances who want a gentle, plant-based enzyme formula that supports broad-spectrum digestion.
Usage Recommendations
Take 1 capsule before or during meals. For heavier meals, up to 2 capsules may be taken. Consistency matters—use with every meal for best results.
Summary: Naturenetics DigestWise is a well-balanced, vegan-friendly enzyme supplement ideal for sensitive stomachs. With 10 targeted enzymes and a clean-label formulation, it’s a solid choice for daily digestive support without unnecessary additives or harsh ingredients.
4. Best Enzyme-Probiotic Combo for Daily Gut Health: GoBiotix Digestive Enzymes (60 Capsules)

Price: Price not available
GoBiotix Digestive Enzymes is a plant-based formula that combines digestive enzymes, prebiotics, and probiotics in one convenient capsule. Designed for both men and women, it aims to support gut health, aid nutrient absorption, and ease common digestive issues like bloating, gas, and food sensitivities.
Key Benefits
- Supports digestion of gluten, dairy (lactose), fats, carbs, and proteins
- Includes probiotics and prebiotics for improved gut flora balance
- Helps reduce bloating, indigestion, and irregularity
- Suitable for those with gluten or dairy sensitivities
- Vegan-friendly and designed for daily use
Key Ingredients
- Digestive Enzyme Blend: Includes protease, amylase, lipase, lactase, cellulase, and more to support broad-spectrum digestion
- Probiotics: Lactobacillus acidophilus for gut balance
- Prebiotics: Fructooligosaccharides (FOS) to nourish beneficial bacteria
- Form: Vegetable capsule
- Dosage: 1 capsule per serving, 60 servings per bottle
Pros
- Combines enzymes, probiotics, and prebiotics in one formula
- Plant-based and non-GMO
- Manufactured in a GMP-certified facility
- Easy-to-swallow capsules
Cons
- Probiotic content may be low for those seeking high-potency probiotic support
- Only 60 capsules per bottle (1-month supply if taken twice daily)
Customer Feedback:
- Value for Money: Many users say the product is worth the price due to its multi-action formula combining enzymes and probiotics.
- Effectiveness: Customers report feeling less bloated, with more regular digestion and better tolerance to gluten and dairy.
- Ease of Use: Capsules are small and easy to take, with no taste or aftertaste.
- Overall Satisfaction: Users appreciate the simplicity of a 3-in-1 formula, especially those managing multiple digestive issues.
Best Suited For
- Individuals with gluten or lactose sensitivity
- Those who prefer a supplement that includes enzymes, probiotics, and prebiotics in one capsule
- People seeking daily digestive support for general gut health
Usage Recommendations
- Take 1 capsule before meals for best results
- For heavier meals, some users opt for 2 capsules
- Can be taken daily as part of a gut health routine
Summary: GoBiotix Digestive Enzymes stands out for its 3-in-1 formula with enzymes, probiotics, and prebiotics—making it ideal for users seeking comprehensive gut support in a single plant-based capsule.
5. Best Value Digestive Enzymes: Nutricost Digestive Enzymes 620mg (120 Capsules)

Price: Price not available
Nutricost Digestive Enzymes offers a no-frills, affordable supplement designed to support digestion and nutrient absorption. With 620 mg of enzyme blend per serving, this product is ideal for users looking for broad digestive support without paying for extra features like added probiotics.
Key Benefits
- Aids in breaking down proteins, fats, carbohydrates, and fibers
- Supports relief from occasional gas, bloating, and indigestion
- Helps improve overall nutrient absorption
- Affordable for long-term daily use (120 capsules per bottle)
- Non-GMO and gluten-free formula
Key Ingredients
Each serving (1 capsule) contains 620 mg of a comprehensive enzyme blend, including:
- Protease
- Amylase
- Lipase
- Lactase
- Cellulase
- Bromelain
- Papain
- Invertase and more
- Form: Capsule (120 capsules per bottle / 120 servings)
Pros
- High dose of broad-spectrum enzymes per capsule
- Only 1 capsule per serving, simple and convenient
- Made in a GMP-compliant, FDA-registered facility
- Excellent value per serving—great for long-term users
Cons
- No probiotics or prebiotics included
- May not target specific gut health needs like gluten or dairy intolerance
- Not vegan (contains gelatin capsule)
Customer Feedback:
- Value for Money: Highly rated for its affordability and generous 120-capsule count. Many users find it one of the best low-cost options on Amazon.
- Effectiveness: Most customers report noticeable improvements in digestion, less bloating, and better comfort after meals, especially high-protein or fatty meals.
- Ease of Use: Easy to take, with no strong smell or aftertaste. One capsule per meal is convenient.
- Side Effects: Very few reports of side effects—well tolerated by most users.
- Overall Rating: A popular budget pick, especially for those wanting to support digestion without the extras.
Best Suited For
Budget-conscious individuals who want a reliable enzyme formula for general digestive support without added probiotics or specialized features.
Usage Recommendations
Take 1 capsule before meals. Best results are seen when taken with the first bite of food, especially for larger meals.
Summary: Nutricost Digestive Enzymes is a straightforward, cost-effective choice for daily digestive support—ideal for those who want essential enzymes in a simple formula without extra ingredients.
6. Best Plant-Based Formula: Sports Research Digestive Enzymes with Probiotics & Ginger (90 Capsules)

Price: Price not available
Sports Research Digestive Enzymes combines broad-spectrum enzymes, probiotics, and organic ginger root in a clean, vegan-friendly formula. Designed to support digestion of protein, dairy, carbs, and sugars, it’s ideal for those following plant-based, gluten-free, or dairy-sensitive diets.
Key Benefits
- Aids digestion of proteins, carbs, fats, and sugars
- Helps relieve gas, bloating, and indigestion
- Supports gut health with 1 Billion CFU probiotics
- Includes ginger to promote gastrointestinal comfort
- Ideal for plant-based and sensitive diets
Key Ingredients
Each serving (1 veggie capsule) provides:
- Digestive Enzyme Blend (255 mg) – Includes amylase, protease, lactase, lipase, bromelain, papain, cellulase, hemicellulase, and more
- Probiotic Blend (1 Billion CFU) – Bacillus coagulans for gut balance
- Organic Ginger Root (50 mg) – Traditionally used to soothe the digestive tract
Form: Veggie capsules. Standard dose: 1 capsule per meal.
Pros
- Vegan certified, Non-GMO Project Verified
- Contains probiotics and ginger for added gut and anti-inflammatory support
- No fillers, artificial ingredients, soy, or gluten
- Clean-label, made in cGMP-compliant facility in the USA
Cons
- Slightly higher price per capsule
- Probiotic dose is modest (not a full-spectrum gut probiotic formula)
- Some users may need a stronger dose for high-fat or heavy meals
Customer Feedback
- Value for Money: Customers find the price fair considering the clean label, added probiotics, and ginger extract, though it’s not the cheapest.
- Effectiveness: Many users report less bloating, smoother digestion, and better comfort after heavy or dairy-containing meals.
- Ease of Use: Capsules are easy to take with meals, and the addition of ginger is praised for reducing discomfort.
- Side Effects: A few sensitive users noted slight stomach cramping; otherwise, very well tolerated.
- Overall Rating: Widely appreciated for its gentle but effective formula, especially by vegan and dairy-sensitive users.
Highlighted Ingredients
- Digestive Enzyme Blend (255 mg): Includes enzymes like protease, amylase, lactase, lipase, bromelain, papain, hemicellulase
- Bacillus coagulans (1 Billion CFU): A resilient probiotic for gut balance
- Organic Ginger Root (50 mg): For digestive soothing
Best Suited For
Those seeking a plant-based enzyme formula with added gut support and ginger – particularly vegans, vegetarians, and individuals with sensitive stomachs or mild food intolerances.
Usage Recommendations
Take 1 capsule before or with meals. Best results are seen when used consistently, especially for meals containing dairy, protein, or carbs.
Summary: Sports Research Digestive Enzymes is a top choice for clean-label, plant-based digestive support. With enzymes, probiotics, and organic ginger, it’s a gentle yet effective option for daily gut wellness—especially for those avoiding dairy or artificial additives.
7. Best for Gluten Sensitivity: MaryRuth Organics Gluten Enzymes (60 Capsules)

Price: Price not available
MaryRuth Organics Gluten Enzymes is a targeted digestive enzyme supplement designed to help break down gluten and other challenging food components. Ideal for those with gluten sensitivity, it supports nutrient absorption and overall gut comfort. Produced by MaryRuth Organics—a trusted brand in clean, vegan supplements—this product is vegan, non-GMO, and free of common allergens.
Key Benefits
- Supports digestion of gluten and related proteins
- May ease occasional bloating and indigestion from hidden gluten
- Promotes nutrient absorption from hard-to-digest foods
- Great for sensitive stomachs and restrictive diets
- Vegan, gluten-free, soy-free, dairy-free
Key Ingredients
- DPP-IV (Dipeptidyl Peptidase IV): Key enzyme for breaking down gluten proteins
- Other enzymes: Includes protease, amylase, lipase, cellulase, and lactase for broad-spectrum digestive support
- Form: Vegan capsules
- Suggested Use: 1 capsule before meals (especially when consuming foods that may contain gluten)
Pros
- Specifically designed for gluten digestion
- Broad enzyme blend for additional support
- Free from artificial colors, fillers, and major allergens
- Manufactured by a well-known clean-label brand
- Easy-to-take capsules suitable for daily or occasional use
Cons
- Not intended for individuals with celiac disease
- May not fully prevent symptoms if large amounts of gluten are consumed
- Slightly more expensive per capsule compared to general digestive enzyme blends
Customer Feedback
- Value for Money: Many customers consider it a good investment for peace of mind when eating out or traveling.
- Effectiveness: Users report fewer digestive issues when accidentally exposed to gluten, with added comfort during meals.
- Ease of Use: Small capsules, simple 1-a-day use. Convenient for those managing gluten sensitivity.
- Overall Satisfaction: Highly praised for those with mild gluten intolerance or looking to support gut health on a clean, vegan protocol.
Best Suited For
People with non-celiac gluten sensitivity, or those who want extra digestive support when eating out or consuming gluten-containing foods unknowingly. Also suitable for clean-eating individuals avoiding animal-derived ingredients.
Usage Recommendations
Take 1 capsule prior to meals that may contain gluten or hard-to-digest grains. Not a replacement for a strict gluten-free diet if medically necessary, but a helpful support tool.
Summary: MaryRuth Organics Gluten Enzymes is a gentle, plant-based solution for gluten-sensitive individuals looking to reduce digestive discomfort and improve nutrient absorption—especially when eating out or exposed to hidden gluten.
Benefits of Taking Digestive Enzyme Supplement
Certain factors such as age, increased stress, or poor nutrition can slow down enzyme production. This means that the food you eat doesn’t break down properly.
Digestive enzyme supplement is of great help under these circumstances. It can boost your body’s natural digestion when it is needed.
Some of the benefits of taking digestive enzyme supplement are:
Helps in Better Digestion
If your body slows down your digestive enzyme production, it means the food that you eat is not digested properly. This results in your body not getting enough nutrients. Improper digestion can also put unnecessary stress on your digestive tract.
Digestive enzyme supplements that are plant-based and derived from microbes help support your digestion, thus preventing multiple digestive disorders.
Helps in Better Nutrient Absorption
Better digestion means enhanced nutrient absorption. These digestive enzyme supplements boost the breakdown of carbohydrates, proteins, and fats into smaller molecules so that they can be absorbed easily.
Helps Reduce Digestive Problems
Bloating is a common digestive problem usually caused by certain foods. Complex carbohydrates such as beans, vegetables, and grains are some of them which are difficult to digest.
Enzymes such as alpha-galactosidase and cellulase break down these complex carbohydrates into simpler forms, thus reducing conditions like gas, bloating, and stomach pain (13).
Similarly, lactose present in milk and milk products commonly cause gas and bloating in some. Almost 68% of the world’s population suffer from lactose intolerance. Digestive enzymes such as lactase help reduce symptoms of poor dairy digestion.
Reduces Acid Reflux
Acid reflux, also known as gastroesophageal sphincter (GERD) is a kind of digestive disorder where the stomach’s content travels back into the esophagus. This causes heartburn. Digestive enzyme supplements have helped reverse this by emptying your stomach.
Provides Relief from Inflammatory Bowel Disease (IBD)
Inflammatory Bowel Disease (IBD) is a group of intestinal disorders that causes inflammation or destruction of the digestive tract leading to sores and narrowing of the intestines. It can be extremely painful and in some cases can be fatal. Symptoms include diarrhea, bleeding ulcers, bowel obstruction, and anemia.
Digestive enzyme supplements such as pancrelipase (PEZ), have been found to be effective in reducing IBS symptoms. PEZ is a combination of lipase, protease, and amylase which are produced by the pancreas.
May Help Manage Irritable Bowel Syndrome (IBS)
Irritable Bowel Syndrome affects the large intestine and can cause digestive problems such as bloating, gas, and constipation. Digestive enzyme supplements help break down complex food to simpler substances and lactobacilli and probiotics present in them help with indigestion.
May Help People with Type 2 Diabetes
Insulin is produced in the pancreas and is the digestive enzyme that regulates your glucose metabolism. In the case of people suffering from type 2 diabetes, the ability of our body to produce sufficient insulin is reduced.
Studies have shown that digestive enzyme supplementation can help better control blood sugar (14).
Summary: Digestive enzyme supplements have shown to help deal with several gastro-intestinal and digestive problems and can help reduce the severity of IBS and IBD.
The Dosage Instructions for Digestive Enzymes Supplements
The general dosage of digestive enzymes supplements is based on the quantity and type of food consumed. It is not dependent on the age or weight of the user (15).
It is advisable to start with only one capsule of the supplement. The label on the product states the serving size. Different supplements of these enzymes are produced for different tasks in the body.
The dosage consumed should be able to break down all the food eaten in the 60 to 90 minutes when present in the stomach together.
A physician can help determine the right dosage based on the specific needs of the individual. Experimenting with necessary care will help in finding the right dosage of digestive enzymes.
Summary: Initially only one capsule should be consumed to check if it is effective. A physician’s recommendation will be helpful.
The Side-Effects and Risks of Digestive Enzymes Supplements
Most forms of over-the-counter digestive enzyme supplementation are considered safe when its use is directed by a physician. However, some side-effects of consuming digestive enzymes may occur.
Diarrhea, abdominal cramping or pain, headache, neck pain, and nasal congestion are some of the side-effects. A doctor’s advice will be helpful, as the benefits of these supplements are greater than the chance of severe reactions.
People who are taking medicines for blood thinning should avoid continuous use of digestive enzyme supplements (16).
It is important to check the sources of these enzymes as some of them are made from animals or microorganisms (17). If any kind of reaction continues for a long time you should contact your doctor or pharmacist.
Frequently Asked Questions (FAQs)
Why is an Enzyme Supplement Needed When Fresh Foods Have Them?
Enzymes present in fresh foods will take a longer time for proper digestion. These foods may not contain all the required enzymes.
The supplements offer a concentrated form that can be added to any diet for faster digestion. These products are beneficial especially for people who consume high amounts of cooked or processed food.
What is the Best Time for Taking These Enzymes?
Digestive enzymes can be taken before meals, during or at the end of the mealtime. It works when it is in contact with the food that stays in the stomach for up to 90 minutes.
Vegetable capsules take longer to dissolve, so taking them for at least 20 to 30 minutes before eating can be more beneficial.
Are There any Side-effects to Children Taking Digestive Enzymes?
Some reactions such as an increase in bowel movement and gas production may take place. There are chances that the child may become hyperactive and more sensitive to pain.
It is important to consult a physician before starting on a course of digestive enzymes for children.
How to Choose a Good Digestive Enzyme Supplement?
A good digestive enzyme breaks down the nutrients that are most common in food items. Those that are high in fat, dairy, or fiber increase indigestion. Lipase, lactase, and cellulase that digests them are found in good digestive enzymes supplements.
Can Pregnant Women Take Digestive Enzyme Supplements?
Digestive enzymes are very helpful during pregnancy. It helps for faster movement of food from the stomach to the intestine.
But please consult your doctor before taking any supplements. The product label should be checked to ensure the ingredients used in the product are safe for the mother and baby.
The Final Note
The use of digestive enzymes to treat conditions like indigestion is becoming popular. Prescribed supplements treat more severe disorders such as IBS.
However, studies in the use of its over-the-counter supplementation require more data. Most manufacturers of digestive enzyme supplements ensure the exclusion of soy, fish, shellfish, eggs, gluten, and other allergens.
Many fruits like pineapples, papaya, avocado, kiwifruit, mango, and banana are the natural sources of digestive enzymes. With proper checks conducted on the content and verification of ingredient sources, supplements of digestive enzymes are increasingly being used today.
It is advisable to check with your physician before starting on a course of digestive enzymes. A consultation becomes necessary if you are on other medications (18).





