The 6 Best Nitric Oxide Supplements

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Nitric Oxide Supplements are widely consumed because of the apparent health benefits that they provide.

L-arginine and L-citrulline are two popular non-essential amino acids that are used in such supplements. Both these lead to an increase in the production of nitric oxide in the body.

Nitric oxide is very critical for the health of the blood vessels. It acts as a vasodilator by relaxing the muscles of the vessels. It is also known to promote the release of insulin and growth hormones (1, 2).

Owing to their perceived benefits, many people take nitric oxide supplements to enhance their workout sessions or boost their libido (3, 4, 5).

However, as with all supplements, they work best with a combination of the right diet and exercise.

Let us take a look at some of the top nitric oxide supplements in the market, and review their advantages, dosages, and side effects.

Our Top Picks

1. Best Pre-Workout Nitric Oxide Supplement: Snap Supplements Nitric Oxide Booster

2. Best Gluten-Free Nitric Oxide Supplement: BulkSupplements AAKG

3. Best Nitric Oxide Supplement for Virility: VigRX Nitric Oxide Support

4. Best Nitric Oxide Supplement Pills: UMZU Redwood Nitric Oxide Supplement

5. Best Nitric Oxide Powder: Old School Vintage Blast Pre-Workout

6. Best Nitric Oxide Supplement With Beetroot: Havasu Nutrition L-Arginine Nitric Oxide Booster

1. Best Pre-Workout Nitric Oxide Supplement: Snap Supplements Nitric Oxide Booster

Snap Supplements Nitric Oxide Booster is designed to support healthy blood circulation, energy, and endurance, making it a popular choice for both men and women looking to enhance their workouts and overall wellness. It contains key ingredients like L-Arginine, L-Citrulline, and botanicals like Muira Puama and Tribulus Terrestris.

Benefits:

• Promotes nitric oxide production, improving blood flow and circulation.

• Boosts energy and workout performance, particularly in pre-workout settings.

• Supports muscle recovery and cardiovascular health.

• Enhances stamina and endurance, making it ideal for fitness enthusiasts.

What it Contains:

• L-Citrulline and L-Arginine for blood flow optimization.

• Tribulus Terrestris and Muira Puama for cardiovascular health and natural energy.

• Panax Ginseng for its adaptogenic and stamina-boosting properties.

Pros:

• Provides a noticeable energy boost and increases workout performance.

• Helps with faster recovery post-workout.

• Promotes better blood flow and heart health.

• Formulated in a GMP-certified and FDA-registered facility, ensuring quality and safety.

Cons:

• Some users find it a bit pricey compared to other nitric oxide boosters.

• A few customers reported it took time to notice significant effects.

Customer Feedback:

Effectiveness: Customers are impressed by its effectiveness, especially the boost in workout performance and muscle pumps.

Energy Level: Most users appreciate the energy surge it provides, particularly during workouts.

Value for Money: While generally considered good value, a few customers felt it was on the expensive side.

Nitric Oxide Boost: Customers love the improved circulation and pump quality, with noticeable benefits in both workout performance and overall well-being.

Summary: Snap Supplements Nitric Oxide Booster offers solid support for energy, endurance, and circulation. It’s particularly effective for fitness enthusiasts looking to boost their workout performance and promote cardiovascular health. While a bit pricier than other options, its quality and ingredients make it a worthwhile investment for those seeking natural nitric oxide support.

2. Best Gluten-Free Nitric Oxide Supplement: BulkSupplements AAKG

Most health-conscious consumers prefer supplements without artificial sweeteners and flavors. Very few manufacturers provide clean, pure, and quality supplements to their customers’ liking, but BulkSupplements is one of the best-known names in this category.

About BulkSupplements AAKG (L-Arginine Alpha-Ketoglutarate)

AAKG is a compound of L-Arginine and Arginine Alpha-Ketoglutarate and is known to increase the production of nitric oxide in your body more than L-Arginine alone. BulkSupplement’s AAKG is popular with bodybuilders owing to its claim of increasing muscle mass, improving energy, and boosting performance by increasing nitric oxide levels.

Available in the powder form, the supplement contains only AAKG and is free from added sugar, additives, flavors, gluten, yeast, dairy, and soy.

In addition to being third-party tested and lab-verified, all BulkSupplement products are made in the USA, in an FDA-approved facility following the cGMP guidelines.

What it Contains:

Each serving (2600 mg) of L-Arginine Alpha-Ketoglutarate AAKG BulkSupplements contains the following:

  • L-Arginine – 1768 mg
  • Alpha-Ketoglutarate – 702 mg

The supplement is available in packs of 100 gms, 250 gms, 500 gms, 1 kg, 5 kg, and 25 kg. One 100 gm container of BulkSupplements AAKG includes 38 servings of 2600 mg (or one teaspoon) each.

BulkSupplements recommends taking up to three such servings in a day on an empty stomach for best results.

You can usually avail discount offers on subscribing to the product for recurring deliveries.

The Pros:

  • Gluten-free
  • Clean and pure formula
  • Free of sugar, soy, and other additives
  • Made in the USA

Summary: BulkSupplements is one of the most recognized brands in the world of health supplements, and is known for quality products. BulkSupplements AAKG (L-Arginine Alpha-Ketoglutarate) is a clean, raw, and gluten-free nitric oxide supplement, which helps the body during workout and bodybuilding sessions.

3. Best Nitric Oxide Supplement for Virility: VigRX Nitric Oxide Support

One of the effects of nitric oxide on the human body is that it helps rush the blood to your nether areas, which results in a firm erection. With age and other factors, the body becomes less efficient in performing this function naturally, giving rise to the need for supplements.

About VigRX Nitric Oxide Support

VigRX Nitric Oxide Support is a stimulant-free nitric oxide supplement that uses a unique blend named Volex.

Volex is a trademark of Kyowa Hakko, an international health ingredients manufacturer, which is a clinically studied blend of Kyowa’s L-Citrulline and Kyowa’s L-Arginine.

According to a citation on the VigRX Nitric Oxide website, the blend was tested during research at the Fukada clinic in Japan, which came out with the result that the blend was efficient by 40 percent than either L-Arginine alone, or L-Citrulline alone, in maintaining sexual stamina and erection.

Velox, the main ingredient of the supplement, is a patented, vegetarian, non-GMO blend that is made in the USA.

What it Contains:

Each serving (3 pills) of VigRX Nitric Oxide contains:

  • Velox – L-citrulline & L-Arginine – 3 grams

Each bottle of VigRX Nitric Oxide contains 90 tablets or 30 servings of three tablets each. The container’s instruction says it is ideal for taking the dosage with water, on an empty stomach in the morning.

The company also offers a 67-day money-back guarantee if you don’t feel the desired result within this period.

The Pros:

  • Uses the patented formula Velox
  • Made in the USA
  • Non-GMO and Vegetarian formula
  • 67-days money-back guarantee

Summary: VigRX Nitric Oxide Support is a product aimed to address your sexual needs. It uses a patented formula designed by Kyowa Hakko, a leading Japanese firm of biotech. The product is ideal for those who are looking to restore their flagging sexual stamina as a result of dropping nitric oxide levels.

4. Best Nitric Oxide Pills: UMZU Redwood Nitric Oxide Supplement

UMZU Redwood Nitric Oxide Supplement is designed to support healthy blood flow and circulation. Formulated with natural ingredients like vitamins, garlic, and L-Leucine, it offers a holistic approach to improving stamina, energy, and immunity. It’s a vegan alternative to traditional supplements for nitric oxide support.

Benefits

• Enhances blood circulation for improved oxygen delivery.

• Boosts stamina and energy levels throughout the day.

• Supports immune health with ingredients like Vitamin C and garlic.

• Promotes better recovery and overall well-being.

What it Contains

The supplement includes Vitamin C, garlic root powder, horse chestnut seed extract, maritime pine bark extract, L-Leucine, and lactotripeptide (VasoDrive-AP®). These ingredients work synergistically to enhance blood flow, energy, and immune function.

Pros

• Vegan-friendly and easy to consume.

• Natural ingredients support multiple health benefits.

• Helps improve energy and endurance.

Cons

• Some customers mention the price being a bit high.

• A few reviews indicated minor side effects like digestive discomfort.

Customer Feedback

Most customers are satisfied with the effectiveness of the product, noting that it increases energy, improves blood circulation, and supports stamina. However, some users experienced side effects and felt that the price was on the higher side compared to similar supplements.

Summary: UMZU Redwood provides a natural, vegan-friendly boost to your energy, circulation, and overall health. With its carefully chosen ingredients, it’s a solid option for those looking for enhanced stamina and immunity support, although the price might be a consideration for some.

5. Best Nitric Oxide Powder: Old School Vintage Blast Pre-workout

Vintage Blast is one of the best nitric oxide supplements in the powder category. It’s a pre-workout mix that is designed to work in two stages, delivering two different sets of nutrients to the body to render you optimally charged during your workouts. The deferred delivery is designed based on the digestive and assimilative properties of different nutrients.

About Old School Vintage Blast Pre-Workout

Old School is a California-based food supplement firm and Vintage Blast is one of its most popular products. Vintage Blast consists of six different types of amino acids, four different types of B vitamins, vitamin C, and other minerals to boost your metabolism and the production of nitric oxide in your body.

The supplement has no artificial sweeteners and is sweetened using stevia. The nitric oxide powder is vegetarian and suitable for those following the keto diet as well. Furthermore, it has no dairy, gluten, and is also GMO-free.

What it Contains:

Each serving (one scoop or 15.3 gm) of Old School Vintage Blast Pre-workout contains:

Stage 1 Group: Start Strong

  • L-Citrulline Malate – 5000 mg
  • Beta-Alanine – 1000 mg
  • L-Arginine AKG – 1000 mg
  • L-Carnitine Tartrate – 250 gm
  • Caffeine Anhydrous – 150 mg

Stage 2 Group: Finish Strong

  • D-Aspartic Acid – 2000 mg
  • N-Acetyl L-Tyrosine – 250 mg
  • Microencapsulate Caffeine – 100 mg

Other ingredients include B vitamins, stevia leaf extract for sweetness, pineapple fruit powder, and natural fruit and vegetable juice. This product is available in the blueberry lemonade flavor.

Each container of Old School Vintage Blast contains 306 gm of supplement powder and includes 20 servings of 15.3 grams each. It is recommended to take a serving by mixing it with water, 15-30 minutes before the workout.

The Pros:

  • Non-GMO and Gluten-free
  • Suitable for vegetarians and keto-friendly 
  • No artificial sweeteners 
  • Two-part delivery of nutrients in the body for sustained results

Summary: Old School is one of the more trusted names in the market. Its Vintage Blast is unique in that it imparts the nutrients value in a graded manner for a long and sustained energy boost, which lasts the entire period of your workout. The fact that it contains no added sweeteners and is suitable for vegetarians makes it all the more appealing.

6. Best Nitric Oxide Supplement With Beetroot: Havasu Nutrition L-Arginine Nitric Oxide Booster

The world of health supplements is rife with products that deliver temporary results and fail to offer sustained benefits. This is usually due to substandard ingredients or quality. It is hence important to look for non-habit forming natural products that deliver long-term sustainable results.

About Havasu Nutrition L-Arginine Nitric Oxide Booster

Havasu Nutrition is a US-based health supplements firm known for products made from natural sources. The firm boasts of manufacturing all its products at an FDA-approved facility that is certified with Good Manufacturing Practices (GMP).

Havasu Nutrition L-Arginine Extra Strength is a non-GMO blend of amino acids and beetroot extracts that claims to increase the production of nitric oxide in your body. Ideal for both men and women, this product is perfect for anyone who wants to give their workout a boost.

What it Contains:

Each serving (2 capsules) of Havasu Nutrition L-Arginine Extra Strength contains:

  • L-Arginine HCL – 400 mg
  • AAKG (L-Arginine Alpha-Ketoglutarate) — 400 mg
  • L-Citrulline Malate – 400 mg
  • Beetroot powder (Beta Vulgaris) – 100 mg

Each bottle of Havasa Nutrition contains 60 capsules constituting 30 servings. It is recommended that you take each serving of two capsules right before your workout for maximum results. Also, there is a 60-day money-back guarantee if you are not satisfied with the results.

The Pros:

  • 60 days money-back guarantee
  • Beetroot powder for increase blood pressure
  • Made in the USA 
  • Non-GMO

Summary: Havasu Nutrition L-Arginine Extra Strength is an ideal product for both men and women with a limited budget to spend on food supplements. The product is one of the best nitric oxide supplements with beetroot. You can easily make this a part of your health and workout regimen.

The Dosage Instructions for Nitric Oxide Supplements

We’ve seen that nitric oxide supplements are available as capsules, pills, and in the form of powder. No specific studies have been undertaken to establish the daily requirement of L-arginine and L-citrulline.

However, some sources say that 5 grams of L-arginine is consumed daily through diet and is converted to nitric oxide and is used by the body for different functions (6).

When taken in appropriate limits, nitric oxide hasn’t shown any significant side effects (7, 8).

But, remember, since these supplements have not been proven to treat any medical conditions nor regulated by the FDA, they should be taken under expert guidance to avoid any severe health complications.

As far as the manufacturers are concerned, they usually suggest higher doses of their supplements for maximum benefit. Depending on whether it is in the form of tablets or powder, you can be required to take 2-3 servings each day. Most manufacturers recommend taking the supplement before the workout for the best results.

Please note that your nitric oxide levels can also increase by the intake of nitrate-rich foods, like beetroot, garlic, green leafy vegetables, broccoli, cauliflower, oranges, bananas, etc. Legumes, dairy products, meat, and poultry also help achieve optimal levels of the amino acids that produce nitric oxide in the body (9, 10, 11, 12, 13).

So, please be careful of your diet while taking nitric oxide supplements.

Summary: While there are no definitive studies that have helped set the daily intake value of nitric oxide, it is best to take it in moderation, as per the manufacturer’s suggestion. It would be best to set the dosage and discuss any change in it, with your physician. Also, remember to take into account all the natural sources of nitric oxide in your diet.

The Side Effects of Nitric Oxide Supplements

Nitric oxide supplements are generally not known to cause any severe adverse effects. However, some mild side effects may include the following:

  • Diarrhea
  • Nausea
  • Heart Palpitations
  • Bloating etc.

Similarly, nitric oxide supplements are not recommended for people who have allergies or asthma, cirrhosis, or had heart attacks in the past (14).

Those with the rare genetic disorder known as Guanidinoacetate methyltransferase should also not use the nitric oxide supplements owing to their body’s inability to convert arginine into creatine.

The supplements may also interfere with existing medication, so be sure to check with your doctor before taking the supplement.

There are isolated cases of more severe side effects, some of which also resulted in increased chances of death after undergoing heart surgery (15).

Summary: Though the consumption of nitric oxide supplements is considered safe with no significant side effects, those with underlying health conditions should avoid using these supplements. There is clearly a greater need for detailed studies examining the side effects of these supplements to help administer more accurate dosages.

Frequently Asked Questions (FAQs)

Who Should Consume Nitric Oxide Supplements?

Nitric oxide supplements should be taken by those looking to enhance their athletic performance. The use of supplements is known to boost workout performance by increasing blood flow to muscles.

Those suffering from mild to moderate erectile dysfunction could also look at these supplements as a possible remedy for their problem. Studies show that supplements relax the penis muscles allowing increased blood flow, causing an erection (16). However, be sure to check with your physician first.

Can Pregnant Women With High Blood Pressure Take Nitric Oxide Supplements?

Most manufacturers caution pregnant or lactating women, along with people who have pre-existing conditions or medications, to avoid nitric oxide supplements. While one research has shown that women may benefit from reduced blood pressure, it is to avoid such supplements during pregnancy (17).

Even people who take these supplements and develop side effects must discontinue their usage and contact their healthcare provider.

Do L-Arginine Supplements Trigger Allergy?

Allergies are not widely reported upon consuming L-arginine supplements. However, a few incidents show an increase in histamine production.

This happens as a response to the supplements when the body considers the arginine supplements as a harmful toxic foreign body. Allergies could also lead to swelling of the face, neck, etc. 

The supplements could also cause serious side effects in those suffering from asthma.

Are Nitric Oxide Supplements Effective?

As a compound, nitric oxide had definite benefits for the human body. However, there is no certainty over the quantity and source of nitric oxide to be chosen for the best results. Many athletes and bodybuilders who take the supplements report quick benefits, whereas others may take weeks.

The results also depend on your lifestyle, and may thus, vary significantly from individual to individual. There is certainly a requirement for a comprehensive study that analyzes all these factors.

The Final Note

Nitric oxide supplements are gaining popularity owing to their many perceived health benefits.

Although they do not have serious side effects, they could pose problems for people with underlying health conditions of heart, kidneys, etc.

With so many products easily available, it is recommended that you conduct a detailed research about the ingredients before choosing the right supplement for you. 

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