Best 5 CLA Supplements for Fat Loss & Muscle Support in 2025

CLA, or conjugated linoleic acid, is a natural trans-fat and has become a trending topic of interest amongst fitness enthusiasts and those who are in search of safe and natural weight loss supplements.

Healthy food sources like meat and dairy products are rich in CLA. As it is not an essential amino acid, it is not produced in our body and has to be taken in the form of supplements to enjoy its benefits.

CLA can decrease body fats by enhancing metabolism. It knocks down the action of lipoprotein lipase, an enzyme responsible for fat storage (1).

It encourages the body fat breakdown and is instrumental in the destruction of adipose cells (2).

CLA supplements are available commercially in different forms like softgels and powders. This article gives you a list of the top CLA supplements that you can purchase from the best CLA brands.

Our Top Picks for CLA Supplements

1. Best Overall CLA Supplement: Nutricost CLA 2400mg (240 Softgels)

• Why? Delivers a total of 2400 mg CLA per serving with 800 mg per softgel, providing great potency at a highly affordable cost. Gluten-free, non-GMO, and produced in a GMP-compliant facility.
• Key Benefits: Supports fat metabolism, lean muscle maintenance, and weight management.
• Best for: Users looking for a high-quality, cost-effective CLA supplement with a large supply.

2. Best Vegan CLA Supplement: Sports Research Vegan CLA 1250mg (90 Softgels)

• Why? Each 1250 mg softgel delivers 1000 mg of active CLA from non-GMO safflower oil. Formulated without soy, gluten, or stimulants, making it ideal for clean-label seekers.
• Key Benefits: Encourages fat metabolism, supports energy balance, and non-stimulant formulation.
• Best for: Those seeking a vegan-friendly, high-potency CLA supplement.

3. Best High-Dose CLA Formula: Zazzee CLA 3600mg (180 Softgels)

• Why? Offers a powerful 3600 mg of CLA per serving, one of the highest doses available. Made from non-GMO safflower oil and manufactured under strict GMP guidelines.
• Key Benefits: Boosts metabolism, helps body composition, and supports muscle tone.
• Best for: Users aiming for maximum strength CLA support in fewer servings.

4. Best Value for Money: Primaforce Max CLA 2400mg (180 Softgels)

• Why? Delivers 2400 mg of CLA per serving with no unnecessary additives at a very competitive price point. Non-GMO, gluten-free, and lab-tested for purity.
• Key Benefits: Promotes fat loss, aids in muscle retention, and supports weight control.
• Best for: Budget-conscious consumers seeking clean ingredients with reliable dosing.

5. Best Starter CLA Supplement: Orphic Nutrition CLA 780mg Active (60 Softgels)

• Why? Offers a concentrated 95% active CLA from safflower oil, with strong user praise for effectiveness and ease of digestion. Ideal for new users testing CLA’s impact.
• Key Benefits: Assists with metabolism, appetite control, and muscle preservation.
• Best for: Beginners or those seeking a simple, affordable CLA option with good absorption.

Rank	Product	Form	Price per Count	Highlight	Key Benefits	Best For
1️⃣	Nutricost CLA 2400mg (240 Softgels)	Softgel	$0.06	Best Overall CLA Supplement	Fat metabolism, lean muscle maintenance, weight management	Users looking for a high-quality, cost-effective CLA supplement with a large supply
2️⃣	Sports Research Vegan CLA 1250mg (90 Softgels)	Softgel	$0.18	Best Vegan CLA Supplement	Fat metabolism, energy balance, stimulant-free	Individuals seeking a vegan, clean-label, high-potency CLA option
3️⃣	Zazzee High Potency CLA 3600mg (180 Softgels)	Softgel	$0.11	Best High-Dose CLA Formula	Boosts metabolism, body composition support, muscle tone	Users aiming for maximum strength CLA in fewer servings
4️⃣	Primaforce Max CLA 2400mg (180 Softgels)	Softgel	$0.08	Best Value for Money	Fat loss, muscle retention, weight control	Budget-conscious buyers looking for purity and potency
5️⃣	Orphic Nutrition CLA 780mg Active (60 Softgels)	Softgel	$0.15	Best Starter CLA Supplement	Metabolism support, appetite control, muscle health	Beginners or casual users testing CLA for weight and energy

1. Best Overall CLA Supplement: Nutricost CLA 2400mg (240 Softgels)

Price: $16.95

Nutricost CLA offers a high-potency, affordable option for those looking to support fat loss and preserve lean muscle. With 800mg of CLA per softgel and 240 softgels per bottle, this supplement provides 80 full servings—making it one of the most cost-effective CLA products on the market. It’s gluten-free, non-GMO, and made in a GMP-compliant, FDA-registered facility.

Key Benefits

• Supports appetite suppression and fat metabolism
• Helps maintain lean muscle during weight loss
• Easy-to-swallow softgels for convenient daily use
• May aid recovery and reduce soreness after workouts
• Backed by strong customer reviews on quality and effectiveness

What It Contains

• CLA (Conjugated Linoleic Acid): 2,400mg per 3-softgel serving (800mg per softgel)
• Safflower Oil (Carthamus tinctorius): 3,000mg per serving
• Form: Softgel capsules
• Suggested Serving: 3 softgels daily with food

Pros

• High CLA content per serving
• Excellent price per count (~$0.06)
• Gluten-free and non-GMO
• Positive reviews on quality, appetite control, and muscle recovery
• Manufactured in the U.S. under strict standards

Cons

• Serving size requires taking 3 softgels
• Some users experience minor stomach discomfort initially
• A few complaints about pill size being slightly large

Customer Feedback:

• Value for Money:
  Most users highlight it as a great deal for the price, offering good results without breaking the bank. It’s praised as affordable and high quality.
• Effectiveness:
  Many users report reduced cravings, better appetite control, and visible results when used with regular workouts. A few say it didn’t work for them.
• Ease of Use:
  Users generally find the softgels easy to swallow, although some mention the pill size is a bit intimidating at first.
• Side Effects:
  Some customers report mild stomach issues during the first few days of use. A few mention digestive discomfort or headaches, especially if taken on an empty stomach.
• Overall Satisfaction:
  With an average rating of 4.5 stars, this CLA supplement is well-received, particularly for its effectiveness and price point.

Best Suited For

• Budget-conscious consumers seeking long-term CLA use
• Individuals focusing on fat loss without losing muscle
• Fitness beginners or regular gym-goers looking for clean support

Usage Recommendations
Take 3 softgels daily with meals. To minimize any potential stomach upset, start with 1–2 softgels per day and increase gradually over the first week.

Summary: Nutricost CLA stands out for its high potency, budget-friendly price, and clean ingredient profile. It’s a reliable pick for anyone seeking affordable fat-loss support with consistent results.

2. Best Vegan CLA Supplement: Sports Research Vegan CLA 1250mg (90 Softgels)

Price: $17.95

Sports Research Vegan CLA 1250 is a premium-quality, plant-based CLA supplement designed for those seeking clean, stimulant-free fat-loss support. Each softgel contains 1,000mg of active CLA from non-GMO safflower oil and is standardized to 80% potency. It’s ideal for vegan, gluten-free, and soy-free lifestyles and is produced in cGMP-compliant facilities in the U.S.

Key Benefits

• Supports fat loss and appetite control
• Helps maintain lean muscle mass during weight reduction
• Boosts energy levels and workout performance
• Fully vegan, gluten-free, and non-GMO
• Softgels are easy to swallow with no aftertaste

What It Contains

• CLA (Conjugated Linoleic Acid): 1,000mg per softgel
• Safflower Seed Oil Concentrate: 1,250mg
• Form: Vegan softgel
• Serving Size: 1 softgel daily (or as directed)

Pros

• High-quality CLA with 80% standardization
• Perfect for vegans and those with dietary restrictions
• Users report improved body composition and energy
• Trusted U.S. brand with consistent manufacturing standards
• Excellent feedback on ease of swallowing and no aftertaste

Cons

• Slightly higher cost per softgel (~$0.18)
• Some users report mild stomach discomfort
• 90-count bottle may not last as long for those taking 2 per day

Customer Feedback:

• Value for Money:
  Despite the price, most users find it reasonably priced for a premium vegan formula. The potency and ingredient quality justify the cost for many.
• Effectiveness:
  Many customers report noticeable fat loss, especially around the midsection, and a reduction in bloating. Some even noted improved energy and body tone.
• Ease of Use:
  Softgels are easy to swallow and don’t leave a bad aftertaste. Users find them convenient to take in the morning or before workouts.
• Side Effects:
  Mixed feedback: some users experienced stomach upset or chest discomfort, while others had no side effects at all and appreciated the gentle formulation.
• Overall Satisfaction:
  With over 12,000 reviews and an average rating of 4.4 stars, this is a top-rated choice for clean, plant-based CLA supplementation.

Best Suited For

• Vegans or individuals with soy/gluten intolerance
• Fitness enthusiasts focused on lean muscle preservation
• Those looking for a non-stimulant CLA to support workouts and fat metabolism

Usage Recommendations
Start with 1 softgel daily, preferably with a meal. Some users take 2 softgels (morning + noon) for enhanced results. If sensitive to oil-based capsules, take with food to reduce potential discomfort.

Summary: Sports Research Vegan CLA 1250 offers a clean, effective, and vegan-friendly CLA option. With high potency, great feedback, and a trusted label, it’s a smart pick for those seeking quality without compromise.

3. Best High-Dose CLA Formula: Zazzee CLA 3600mg (180 Softgels)

Price: $19.97

Zazzee Naturals offers one of the most potent CLA supplements on the market, providing 3600 mg of safflower oil per serving (with 80% CLA). Designed for adults aiming to optimize body composition, it delivers a concentrated dose in just three softgels. The product is non-GMO, gluten-free, and manufactured in a GMP-certified facility in the USA.

Key Benefits

• Helps reduce body fat and promote lean muscle mass
• Aids appetite suppression and calorie control
• Supports healthy metabolism and energy levels
• Maintains skin and joint health
• May improve insulin sensitivity (per user feedback)

Key Ingredients

• Safflower Oil (3600 mg) — standardized to a minimum of 80% CLA
• Delivered in softgel form (gelatin, glycerin, purified water)
• Serving size: 3 softgels (60 servings per bottle)

Pros

• High potency per serving (3600 mg total oil, ~2880 mg CLA)
• Excellent value (only $0.11 per softgel)
• Clean label: non-GMO, gluten-free, all-natural
• Made in the USA with third-party testing

Cons

• Requires taking 3 softgels per dose
• May cause skin reactions or upset stomach in sensitive users
• Some users report it doesn’t work for fat loss without consistent diet/exercise

Customer Feedback:

• Value for Money: Users highly praise it for offering a large dose at a reasonable price. Many find the price-per-pill economical for long-term use.
• Quality: Consistently rated as a high-quality and effective product for weight management and appetite control.
• Effectiveness: Most customers feel it works well in reducing cravings and supporting fat metabolism. Some even reported quick results within days.
• Appetite Suppressant: Helps reduce snacking and manage hunger; a few users reported losing up to 18 lbs in 3 months.
• Ease of Use: Generally considered easy to swallow despite large dosage size.
• Potential Side Effects: A minority of users experienced mild stomach upset or skin irritation (e.g., itchy lips).

Best Suited For

Adults looking for a high-potency CLA formula to support weight loss, muscle retention, and appetite control—especially those who don’t mind a 3-softgel dose.

Usage Recommendations

Take 3 softgels daily, preferably with meals. To reduce side effects, some users suggest starting with 1 softgel and gradually increasing to the full dose.

Summary: Zazzee CLA 3600 delivers exceptional strength per serving and offers outstanding value. It’s a top choice for users who want maximum CLA support in a clean, reliable formula. Just be mindful of the larger dose and watch for rare side effects.

4. Best Value for Money: Primaforce Max CLA 2400mg (180 Softgels)

Price: $14.95

Primaforce Max CLA delivers 2400 mg of conjugated linoleic acid per serving (3 softgels), formulated for both men and women. It’s a non-stimulant fat metabolism support supplement derived from safflower oil. Each bottle provides 180 softgels (60 servings), making it a cost-effective option for long-term use.

Key Benefits

• Supports fat metabolism and weight management
• Helps preserve lean muscle during fat loss
• Non-stimulant formula (no jitters or crashes)
• May enhance body composition with regular use

Key Ingredients

• 3000 mg Safflower Oil
• 2400 mg Conjugated Linoleic Acid (CLA)
  Form: Softgels (3 per serving)
  Standard Use: 1 serving daily with meals

Pros

• High CLA content per serving (2400 mg)
• Very low cost per softgel (approx. $0.08)
• No artificial additives, fillers, or soy
• Third-party lab tested for purity and potency
• Gluten-free, non-GMO

Cons

• Requires 3 softgels per serving
• Not vegan (softgel contains gelatin)
• Fewer reviews compared to more popular brands

Customer Feedback

• Quality: Users highlight the excellent quality and packaging. Comments note “very good quality” and that softgels arrived fast and intact.
• Value for Money: Customers widely agree it’s “competitively priced,” offering solid CLA dosage at a great value.
• Functionality: Reviewers report it “works very well,” helping them lose weight and maintain energy levels.
• Weight Loss: Some users lost significant weight (up to 30 pounds) while using this with workout routines.

Highlighted Ingredients

• CLA (Conjugated Linoleic Acid): 2400 mg per serving – helps support body fat reduction and lean mass retention.
• Safflower Oil: 3000 mg source oil per serving – naturally derived and rich in CLA.

Best Suited For

• Budget-conscious users
• Those seeking stimulant-free fat metabolism support
• Adults looking to reduce body fat while maintaining muscle

Usage Recommendations

Take 3 softgels per day, ideally with meals. Consistent use with diet and exercise may yield better results.

Summary: Primaforce Max CLA stands out as the most affordable high-strength CLA supplement. It’s clean, effective, and ideal for anyone focused on fat loss without stimulants or fillers.

5. Best Starter CLA Supplement: Orphic Nutrition CLA 780mg Active (60 Softgels)

Price: Price not available

Orphic Nutrition CLA is a safflower oil-derived conjugated linoleic acid supplement designed to support weight loss, metabolism, and lean muscle mass. With 60 softgels per bottle and a moderate dose of 780 mg active CLA per day, it offers a wallet-friendly option for beginners or those looking to try CLA without a long-term commitment.

Key Benefits

• Supports fat metabolism and energy levels
• Aids lean muscle retention and body composition
• Helps reduce appetite and cravings
• Contains 95% active CLA content
• Non-stimulant formula with no crash or jitters

Key Ingredients

• CLA (Conjugated Linoleic Acid) – 1000 mg per softgel, with 95% active CLA (approx. 780 mg daily)
• Other ingredients: Gelatin, Glycerin, Purified Water
• Form: Softgel | Serving: 2–3 softgels/day as per label

Pros

• High customer satisfaction for weight loss support
• 95% active CLA – among the highest potency per capsule
• All-natural ingredients and minimal fillers
• No stimulants, jitters, or crash effects reported
• Budget-friendly for short-term trial or first-time users

Cons

• Only 60 softgels per bottle (shorter supply vs. competitors)
• Lower overall daily dose (780 mg CLA) compared to higher-end products
• Some users may require more than 2 softgels to feel effects

Customer Feedback:

• Effectiveness: Many users report noticeable fat loss, appetite control, and metabolism support. One user noted visible results within days, while others appreciated better energy levels and reduced belly fat.
• Metabolism Boost: Customers feel more energized, sleep better, and experience improved workout recovery. Several noted enhanced motivation.
• Weight Loss: Users claim consistent fat reduction, less hunger, and better satiety throughout the day. One mentioned breaking a weight plateau.
• Value for Money: Despite the short supply, most users find it affordable and “worth it” for a high-CLA formula.
• Ease of Use: Widely praised for being easy to swallow with no aftertaste or digestive issues.
• Ingredients: Highly rated for its purity and minimal additives. No adverse side effects noted by most users.
• Potency & Jitteriness: The high-potency formula is well-tolerated without any jittery feelings or energy crashes, making it ideal for sensitive users.

Best Suited For

• Beginners trying CLA for the first time
• Budget-conscious users seeking short-term results
• People sensitive to stimulants who want gentle metabolic support

Usage Recommendations
Take 2–3 softgels daily with meals and water. For best results, combine with a calorie-controlled diet and regular physical activity. Stay consistent for 3–6 weeks to observe significant changes.

Summary: Orphic Nutrition CLA delivers solid metabolic and weight management support with high active CLA content and zero stimulants. While the supply is shorter, it’s a great starter option for anyone new to CLA looking for value and simplicity.

The Dosage Instructions for CLA Supplements

To experience the maximum benefits from CLA supplements you should take them in the right dose at the right hour of the day.

The best way of doing that would be sticking to the manufacturer’s guidelines which are specific for each product. It is necessary to consult your healthcare provider or gym trainer before you start with the supplementation course.

Clinical studies have indicated that an average dose ranging from 3 to 6 grams each day is safe and has brought positive results (3). While the minimum dose to undergo weight loss is 3000mg per day, care should be taken never to exceed the dose above 6000mg/day.

CLA supplements on an empty stomach may make you nauseous, so have a serving with your meal. Moreover, the supplements put a check on the fat absorption when consumed along with any meal.

For those who wish to enhance their exercise performance can consume CLA supplements at least 2 hours before hitting the gym or have them conveniently after the workout.

Summary: Ideally, the daily dose of CLA supplements should fall in between a range of 3grams to 6 grams and should be consumed with meals preferably.

The Side Effects Using CLA Supplements

As CLA is a natural food product, the side effects are minimal and it is quite safe when consumed within the prescribed dosage (4). A few symptoms have been discussed in studies and clinical trials like:

• Nausea
• Diarrhea
• Flatulence
• Fatigue

These mild gastrointestinal side effects could be better understood if we realize that any fatty acid (CLA being one), can cause minor stomach problems when consumed in large doses. Moderation is the key. In the pursuit of quick positive results, you may be tempted to overdose and that’s when the adverse effects kick in.

Summary: CLA supplements are safe in general but may cause minor stomach issues such as nausea and diarrhea when consumed in excessive amounts. 

Frequently Asked Questions (FAQs)

The Final Note

Conjugated Linoleic Acid or CLA can help you shed those extra pounds that just aren’t ready to budge in spite of your constant efforts through a weight loss program or an exercise routine.

CLA decreases body fats by helping them burn off easily and does not allow the fats to be deposited in the body. They can help those who wish to maintain their healthy body composition.

Dairy products and grass-fed beef are rich sources of CLA that are naturally available. CLA supplements, on the other hand, help you attain the recommended daily target which you are not able to reach through dietary sources alone.

Be informed about the ingredients, brand, and customer reviews before picking up a product for yourself as one can never rule the chances for individual variations. 

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