- Our Top Picks
- Comparison Table
- 1. Swanson Chelated Copper 2 mg (Albion Bisglycinate) — Best Overall
- 2. Global Healing Bio-Active Copper (Cu1) — Best RDA-Matched Dose
- 3. Nutricost Copper Glycinate 3 mg — Best Vegan Capsule
- 4. NaturesPlus Copper 3 mg — Best Gluten-Free Tablet
- 5. Micro Ingredients Copper Glycinate Softgels — Best Softgel Option
- 6. Dr. Mercola Copper Bisglycinate — Best Mini Tablet
- Evidence-Based Ingredients
- What Are Copper Supplements?
- Common Signs You May Need Copper Support
- Key Ingredients to Look For
- How to Choose
- Who May Benefit
- Safety and Side Effects
- What Results Can You Expect?
- Lifestyle Tips
- Frequently Asked Questions
- Final Thoughts
Copper is a cofactor for enzymes involved in iron transport (ceruloplasmin), cellular energy production (cytochrome c oxidase), collagen cross-linking (lysyl oxidase), and antioxidant defense (superoxide dismutase). The adult RDA is 900 mcg per day, and the tolerable upper intake level is 10 mg per day.
Most adults meet their needs through food such as shellfish, organ meats, nuts, seeds, and cocoa. Supplementation is most relevant for people with a confirmed deficiency, a history of bariatric surgery or malabsorption, or long-term use of high-dose zinc, which blocks copper absorption.
People with Wilson’s disease, liver disease, or biliary obstruction should not take copper supplements. Because both deficiency and excess cause real harm, please consult your healthcare provider and consider a blood test before starting copper.
Our Top Picks
Best Overall: Swanson Chelated Copper 2 mg — Albion bisglycinate chelate at 2 mg, roughly four cents per tablet.
Best RDA-Matched Dose: Global Healing Bio-Active Copper (Cu1) — Delivers exactly 0.9 mg, matching the adult RDA without overshooting.
Best Vegan Capsule: Nutricost Copper Glycinate — Vegan 3 mg bisglycinate capsule, third-party tested for purity and potency.
Best Gluten-Free Tablet: NaturesPlus Copper 3 mg — Gluten-free 3 mg amino acid chelate from a cGMP-compliant manufacturer.
Best Softgel Option: Micro Ingredients Copper Glycinate Softgels — Copper glycinate in an MCT oil softgel, 250 servings per pouch.
Best Mini Tablet: Dr. Mercola Copper Bisglycinate — Small vegetarian bisglycinate tablets; one tablet supplies 4 mg of copper.
Comparison Table
| Rank | Product | Form | Price/Serving | Best For |
|---|---|---|---|---|
| 1 | Swanson Chelated Copper 2 mg | Tablet, 2 mg copper bisglycinate | $0.04 | Adults who want an affordable long-term daily copper source |
| 2 | Global Healing Bio-Active Copper (Cu1) | Capsule, 0.9 mg cuprous nicotinate | $1.67 | Adults topping up dietary copper who prefer the lowest effective dose |
| 3 | Nutricost Copper Glycinate | Vegan capsule, 3 mg copper bisglycinate | $0.08 | Vegans and vegetarians who prefer capsules over tablets |
| 4 | NaturesPlus Copper 3 mg | Tablet, 3 mg amino acid chelate | $0.14 | People on gluten-free diets who want one tablet a day |
| 5 | Micro Ingredients Copper Glycinate Softgels | Softgel, 4 mg copper glycinate (2 softgels) | $0.06 | People who dislike tablets and don’t require a vegetarian product |
| 6 | Dr. Mercola Copper Bisglycinate | Mini tablet, 4 mg copper bisglycinate | $0.11 | Adults following a clinician’s plan for a higher short-term dose |
1. Swanson Chelated Copper 2 mg (Albion Bisglycinate) — Best Overall
Price: $21.07 (as of October 4, 2026)
Swanson uses Albion’s patented copper bisglycinate chelate, one of the most studied chelated mineral ingredients, at a cost of roughly four cents per tablet.
Key Specs
- Active ingredient + form: Copper as Albion copper bisglycinate chelate
- Dose per serving: 2 mg (222% DV)
- Certifications: None listed on the Amazon listing
- Third-party tested: Not stated on the listing
- Servings per container: 600 tablets (2 × 300-count bottles)
- Price per serving: $0.04 (calculated manually, Price as of October 4, 2026)
Clinical Relevance
In a bisglycinate chelate, copper is bound to two glycine molecules, which keeps it soluble in the gut and reduces direct contact between free copper ions and the stomach lining. A 2 mg dose covers the 900 mcg RDA with margin while staying far below the 10 mg upper limit.
Key Ingredients
- Copper (Albion bisglycinate chelate, 2 mg): Supplies copper for ceruloplasmin, which helps move iron out of storage and into red blood cell production.
Pros
- Branded Albion chelate rather than an unspecified copper salt
- 600 tablets per pack, enough for more than a year and a half
- Small, flat tablets that reviewers find easy to swallow
Cons
- No third-party testing or certification mentioned on the listing
- Contains calcium carbonate and pharmaceutical glaze as fillers
Best Suited For
Adults with a lower-copper diet or long-term zinc use who want a moderate, low-cost daily dose.
Usage Recommendations
Take one tablet daily with water, ideally with a meal to reduce the chance of nausea. Swallow it promptly, since some users notice a metallic taste if the tablet lingers in the mouth.
Customer Feedback
Reviewers consistently describe this as an effective, low-cost copper supplement they plan to keep buying. Many appreciate how small and easy to swallow the tablets are. Some report steadier energy, while a group of long-term users say they noticed changes in hair color and skin texture after months of daily use.
The main complaint is digestive. A minority describe nausea, stomach cramps, or vomiting even at one 2 mg tablet daily. A few also mention a penny-like taste when the tablet sits in the mouth too long.
Summary: Swanson earns Best Overall by pairing a recognized chelated form with a sensible 2 mg dose at the lowest price per serving in this list.
Doctor’s Note
If you also take zinc, separate the two by a few hours, as they compete for absorption. Stop and speak with your doctor if you develop persistent vomiting, abdominal pain, or dark stools.
2. Global Healing Bio-Active Copper (Cu1) — Best RDA-Matched Dose
Price: $49.95 (as of October 4, 2026)
Global Healing’s Cu1 delivers 0.9 mg of copper per capsule, matching the adult RDA exactly instead of exceeding it two- to four-fold like most products here.
Key Specs
- Active ingredient + form: Copper as cuprous nicotinic acid (copper(I) bound to niacin)
- Dose per serving: 0.9 mg (100% DV)
- Certifications: GMO-free, gluten-free, made in a cGMP-certified facility
- Third-party tested: Not stated on the listing
- Servings per container: 30
- Price per serving: $1.67 (calculated manually, Price as of October 4, 2026)
Dose disclaimer: At 0.9 mg, this product contains less copper per serving than the 2–4 mg found in other products on this list. It is designed for daily maintenance rather than higher-dose use under medical supervision.
Clinical Relevance
Copper enters intestinal cells mainly through the CTR1 transporter in its reduced (copper I) form, so supplying cuprous copper is a reasonable design choice on a mechanistic basis. However, there are no published human trials showing that cuprous nicotinate is absorbed better than standard chelates.
Key Ingredients
- Copper (cuprous nicotinic acid, 0.9 mg): Provides copper for cytochrome c oxidase, the final enzyme in the mitochondrial chain that produces cellular energy.
Pros
- Dose matches the RDA, lowering the risk of excess intake with long-term use
- Simple formula: only gum acacia and a cellulose capsule
- Reviewers frequently describe it as gentle on the stomach
Cons
- Most expensive per serving on this list by a wide margin
- Only 30 capsules per bottle
- Label calls for an empty stomach, which some people find harder to tolerate
Best Suited For
Adults who want to top up dietary copper at the RDA level and are willing to pay more for a minimal dose.
Usage Recommendations
Take one capsule daily on an empty stomach, at least two hours before or after a meal. If that causes discomfort, ask your healthcare provider whether taking it closer to a light meal is appropriate.
Customer Feedback
Buyers who track their blood work say this product helps them keep iron-related markers where their clinician wants them. Several reviewers describe it as noticeably easier on the stomach than ionic or liquid copper they had tried before, and others say the formula’s quality and plant-based capsule justify their trust in the brand.
Price is the dominant complaint, with many reviewers calling the cost hard to justify for 30 capsules. A small number also report stomach pain severe enough to stop taking it.
Summary: Cu1 earns Best RDA-Matched Dose because it is the only product here that delivers exactly the adult daily requirement in one capsule.
Doctor’s Note
Anemia has many causes and should be evaluated by a doctor before you rely on any copper supplement for it. Do not combine this with other copper-containing multivitamins without checking your total daily intake.
3. Nutricost Copper Glycinate 3 mg — Best Vegan Capsule
Price: $9.94 (as of October 4, 2026)
Nutricost offers a vegan 3 mg copper bisglycinate capsule that is third-party tested for purity and potency, at about eight cents per serving.
Key Specs
- Active ingredient + form: Copper as copper bisglycinate
- Dose per serving: 3 mg (333% DV)
- Certifications: Vegan, GMO-free, made in an NSF-certified GMP facility
- Third-party tested: Yes (per manufacturer)
- Servings per container: 120
- Price per serving: $0.08 (calculated manually, Price as of October 4, 2026)
Clinical Relevance
Copper bisglycinate is a chelated form that stays soluble across the pH changes of the digestive tract. At 3 mg, it provides more than three times the RDA, which can be useful when a clinician is correcting low copper status but exceeds what most well-fed adults need long term.
Key Ingredients
- Copper (bisglycinate, 3 mg): Supports lysyl oxidase, the enzyme that cross-links collagen and elastin in skin, blood vessels, and connective tissue.
Pros
- Vegan capsule with a short list of inactive ingredients
- Third-party tested for purity and potency
- Four months of supply for under $10
Cons
- 3 mg is higher than most adults need for maintenance
- NSF certification applies to the manufacturing facility, not the product itself
Best Suited For
Vegans and vegetarians who prefer capsules and want a tested, budget-friendly chelated copper.
Usage Recommendations
Take one capsule daily with food. If you only need maintenance-level copper, ask your provider whether taking it every other day is more appropriate.
Customer Feedback
Reviewers repeatedly describe the quality as excellent and the price as fair, and many are repeat buyers. The capsule is considered easy to swallow with no aftertaste. Several users say it sits more comfortably on the stomach than other copper products they had used, and a few associate it with fewer leg cramps or less tingling in the hands.
Negative feedback is limited but worth noting. One reviewer reported stomach cramps and diarrhea and recommended a lower dose for sensitive users. A few reviewers describe giving it to children, which should only happen with a pediatrician’s guidance.
Summary: Nutricost earns Best Vegan Capsule by combining a plant-based capsule, third-party testing, and a low price per serving.
Doctor’s Note
This product is intended for adults. Do not give it to children unless a pediatrician has confirmed low copper levels and set the dose.
4. NaturesPlus Copper 3 mg — Best Gluten-Free Tablet
Price: $12.95 (as of October 4, 2026)
NaturesPlus chelates copper to soy-derived amino acids through its Biotron process, delivering 3 mg per gluten-free tablet.
Key Specs
- Active ingredient + form: Copper as soy amino acid chelate (Biotron process)
- Dose per serving: 3 mg (333% DV)
- Certifications: Gluten-free, made in a cGMP-compliant, FDA- and NSF-registered facility
- Third-party tested: Not stated on the listing
- Servings per container: 90
- Price per serving: $0.14 (calculated manually, Price as of October 4, 2026)
Clinical Relevance
Amino acid chelates bind copper to small protein fragments, which helps keep the mineral soluble and limits interactions with other dietary compounds like phytates. Like other 3 mg products, this exceeds daily needs for most adults and fits best when a higher intake has a clear reason.
Key Ingredients
- Copper (soy amino acid chelate, 3 mg): Supports superoxide dismutase, an antioxidant enzyme that neutralizes superoxide radicals inside cells.
Pros
- Gluten-free formula from a long-established brand
- One tablet per day with no splitting required
- Strong rating distribution, with about nine in ten ratings at four stars or higher
Cons
- Highest price per serving among the chelated tablets on this list
- Chelate is derived from soy, which matters for people with soy allergies
Best Suited For
People on a gluten-free diet who want a single daily tablet and have no soy sensitivity.
Usage Recommendations
Take one tablet daily with a meal. Avoid taking it at the same time as high-dose zinc or iron supplements.
Customer Feedback
Across more than 200 ratings, roughly three-quarters of buyers award five stars and another 14% give four, which signals broad satisfaction with the product. That level of consistency is typical of buyers who reorder a basic mineral supplement because it does what they expect without problems.
About 3% of ratings are one or two stars, so serious complaints are uncommon. Still, the soy-derived chelate makes this a poor fit for anyone with a soy allergy, and the 3 mg dose may be more than diet-sufficient adults need.
Summary: NaturesPlus earns Best Gluten-Free Tablet by offering a simple once-daily chelated tablet from a cGMP manufacturer with consistently high ratings.
Doctor’s Note
If you have a soy allergy, check with your doctor before using an amino acid chelate derived from soy. Avoid stacking this with a multivitamin that also contains copper.
5. Micro Ingredients Copper Glycinate Softgels — Best Softgel Option
Price: $14.99 (as of October 4, 2026)
Micro Ingredients suspends copper glycinate in MCT oil inside a softgel, offering a non-tablet option with 500 softgels per pouch.
Key Specs
- Active ingredient + form: Copper as copper glycinate in MCT oil
- Dose per serving: 4 mg per 2 softgels (444% DV); 2 mg per softgel
- Certifications: Non-GMO, made in a cGMP-compliant facility, free of gluten, soy, and dairy
- Third-party tested: Yes (per manufacturer)
- Servings per container: 250 (500 softgels)
- Price per serving: $0.06 (calculated manually, Price as of October 4, 2026)
Clinical Relevance
Copper glycinate is a chelated form with good solubility, and the softgel format suits people who struggle with pressed tablets. The MCT oil base is a delivery medium; there is no clinical evidence that it increases copper absorption.
Key Ingredients
- Copper (glycinate, 4 mg per 2 softgels): Contributes to dopamine beta-hydroxylase activity, an enzyme needed to make norepinephrine in the nervous system.
- MCT oil (from coconut, amount not specified): Serves as the carrier oil that fills the softgel.
Pros
- Softgel format for people who dislike tablets or capsules
- Third-party lab tested for purity and potency
- Each softgel contains 2 mg, so the dose can be halved easily
Cons
- Gelatin softgel, so not suitable for vegetarians or vegans
- Listed 2-softgel serving (4 mg) is four times the RDA
- Contains coconut, classified as a tree nut for labeling purposes
Best Suited For
Adults who prefer softgels, eat animal products, and want flexibility to take one or two softgels as advised.
Usage Recommendations
The label lists two softgels daily, but one softgel (2 mg) is enough for most maintenance needs. Take it with a meal and confirm the right amount with your healthcare provider.
Customer Feedback
Buyers rate the quality highly, with one reviewer finding it a better experience than a copper sulfate solution they had used before. Several report feeling a difference within a week or a month of use, including better mental clarity, and some expect it to bring low blood copper back into range alongside their doctor’s monitoring.
The 4.4-star rating is the lowest on this list, and with roughly 120 ratings, there is less long-term feedback than for older products. It is also unsuitable for vegetarians and anyone avoiding coconut.
Summary: Micro Ingredients earns Best Softgel Option as the only non-tablet, non-capsule format here, with third-party testing and a flexible 2 mg per softgel.
Doctor’s Note
Taking the full 4 mg daily for months, especially alongside a multivitamin, can push total intake well above need. Ask your provider whether one softgel daily is sufficient for you.
6. Dr. Mercola Copper Bisglycinate — Best Mini Tablet
Price: $19.97 (as of October 4, 2026)
Dr. Mercola packs 4 mg of copper bisglycinate into a small vegetarian tablet, the highest per-tablet dose on this list.
Key Specs
- Active ingredient + form: Copper as copper bisglycinate
- Dose per serving: 4 mg per tablet (444% DV); label also lists an 8 mg, two-tablet daily option
- Certifications: Vegetarian, non-GMO, soy-free, gluten-free
- Third-party tested: Not stated on the listing
- Servings per container: 180
- Price per serving: $0.11 (calculated manually, Price as of October 4, 2026)
Clinical Relevance
Copper bisglycinate is well absorbed and generally gentle on digestion. At 4 mg per tablet, this product is better suited to short-term correction of low copper under supervision than to indefinite daily use.
Key Ingredients
- Copper (bisglycinate, 4 mg): Required for myelin maintenance; copper deficiency is a recognized cause of nerve damage and gait problems.
Pros
- Mini tablets that are easy to swallow
- Vegetarian, soy-free, and gluten-free
- 180 tablets per bottle
Cons
- 4 mg per tablet is high for routine maintenance
- The two-tablet option (8 mg) approaches the 10 mg upper limit
- No third-party testing stated on the listing
Best Suited For
Adults whose clinician has recommended a higher short-term copper dose, such as after years of high-dose zinc.
Usage Recommendations
Take no more than one tablet daily with food unless your doctor has prescribed more. Recheck copper levels after a few months instead of continuing indefinitely.
Customer Feedback
Reviewers often describe the product as more effective than they expected. Some say they felt better within a week, others report more energy, and a few believe their hair looks fuller with fewer grays. One reviewer found it especially helpful after years of taking zinc.
The review pool is small, at under 200 ratings, and much of the feedback is enthusiastic but vague. Some buyers take two tablets daily without mentioning medical guidance, which means 8 mg of copper per day.
Summary: Dr. Mercola earns Best Mini Tablet for its small, clean vegetarian tablet, provided the dose is managed carefully.
Doctor’s Note
The label’s two-tablet serving supplies 8 mg daily, close to the 10 mg upper limit. Long-term intake at that level without monitoring can lead to copper accumulation in the liver, so use the higher dose only under medical supervision.
Evidence-Based Ingredients
Copper (as an essential nutrient)
The body’s need for copper is firmly established. Clinical case series consistently link deficiency to anemia that does not respond to iron, low white blood cell counts, and nerve damage affecting balance and sensation. Randomized trials in people who are not deficient, however, show little measurable benefit from extra copper.
Copper bisglycinate and glycinate
These chelated forms are supported by mechanistic data and animal studies showing good absorption and tolerability. Head-to-head randomized trials in humans comparing chelates with copper sulfate or gluconate are scarce, so “superior absorption” claims should be read as plausible rather than proven.
Cuprous nicotinate (copper I)
The rationale is mechanistic: intestinal cells absorb copper mainly in its reduced copper I form. There are no published human trials comparing this form with standard chelates, so evidence remains at the theoretical and early research stage.
Zinc–copper interaction
This is one of the best-documented findings in this category. Human studies and many case reports show that long-term zinc intake of roughly 50 mg per day or more can block copper absorption and cause deficiency.
Copper and hair color
Tyrosinase, the enzyme that produces melanin, depends on copper, and severe deficiency can lighten hair. Reports of gray hair darkening in people without deficiency are anecdotal and have not been confirmed in controlled trials.
The ingredients in our top picks have strong clinical backing as essential nutrients, with emerging evidence for the specific forms used. They are not treatments for anemia, neuropathy, or any other condition and should not replace medical care.
What Are Copper Supplements?
Copper supplements provide the trace mineral copper in a concentrated form, usually as a tablet, capsule, softgel, or liquid. Doses typically range from 0.9 mg to 4 mg per serving.
The copper is always bound to another compound, such as glycine, citrate, gluconate, sulfate, or nicotinic acid. That partner compound affects how well the copper dissolves, how much is absorbed, and how gentle it is on the stomach.
Copper supplements are designed to fill a gap between dietary intake and the body’s needs. They are most useful when a deficiency is confirmed or likely, rather than as a general wellness booster.
Common Signs You May Need Copper Support
- Anemia that does not improve with iron supplementation
- Low white blood cell counts (neutropenia) on routine blood work
- Numbness, tingling, or unsteady walking without another clear cause
- Long-term use of zinc supplements, especially at 50 mg per day or more
- A history of bariatric surgery, celiac disease, or other conditions affecting absorption
- Unusually pale skin or premature loss of hair pigment alongside other symptoms
These signs overlap with many other conditions. A blood test for serum copper and ceruloplasmin is the only reliable way to confirm low copper status.
Key Ingredients to Look For
The form of copper matters more than the brand name. The table below compares the forms you’ll see on supplement labels.
| Form | Absorption | Notes |
|---|---|---|
| Copper bisglycinate / glycinate | Good | Chelated, generally gentle on the stomach; the most common form in quality supplements |
| Copper citrate | Good | Well absorbed; less common as a standalone supplement |
| Copper gluconate | Moderate to good | Common in multivitamins; well studied in human trials |
| Copper sulfate | Good | Inexpensive, but more likely to cause nausea at higher doses |
| Cuprous nicotinate (copper I) | Unclear | Strong theoretical rationale; no human comparative trials yet |
| Copper oxide | Poor | Very low absorption; best avoided |
| Liquid ionic copper | Variable | Easy to dose, but reviewers frequently report nausea |
For most people, a 1–2 mg dose of copper bisglycinate or glycinate offers the best balance of absorption, tolerability, and safety margin.
How to Choose
Form and bioavailability: Choose a chelated form such as bisglycinate or glycinate, and skip copper oxide.
Dose: For maintenance, 1–2 mg is plenty. Doses of 3–4 mg make more sense for a defined period under medical guidance.
Third-party testing: Look for products tested for purity and potency, since heavy-metal contamination and label accuracy matter in mineral supplements.
Dietary needs: Check for gelatin, soy, coconut, or other ingredients that conflict with your diet or allergies.
Price per serving: Compare cost per serving rather than bottle price. On this list, it ranges from about $0.04 to $1.67.
Who May Benefit
- Adults taking zinc long term for immunity, skin, or eye health
- People who have had gastric bypass or other bariatric surgery
- Individuals with malabsorption conditions such as celiac disease or inflammatory bowel disease
- Anyone whose doctor has found low copper or ceruloplasmin on a blood test
Safety and Side Effects
The most common side effects are nausea, stomach cramps, and a metallic taste. Taking copper with food usually helps.
The tolerable upper intake level for adults is 10 mg per day from all sources combined, including food and multivitamins. Chronic excess can damage the liver.
People with Wilson’s disease, liver disease, or biliary obstruction should not take copper supplements. Copper may interact with penicillamine and trientine, and it competes with zinc and iron for absorption. During pregnancy and breastfeeding, the RDA rises to 1.0 mg and 1.3 mg respectively, but supplements should only be used with a doctor’s approval.
What Results Can You Expect?
If you are deficient, blood markers such as copper, ceruloplasmin, and red and white blood cell counts typically begin to improve within several weeks of supplementation. Full correction may take a few months.
Nerve-related symptoms recover more slowly, and recovery may be partial if damage has been present for a long time. If your copper levels were already normal, you are unlikely to notice a meaningful change.
Lifestyle Tips
- Eat copper-rich foods such as oysters, cashews, sunflower seeds, lentils, and dark chocolate
- If you take zinc, keep the dose within recommended limits and ask whether you need copper alongside it
- Count the copper in your multivitamin before adding a standalone supplement
- Take copper at a different time from high-dose iron or zinc
- Retest blood levels after a few months instead of supplementing indefinitely
Frequently Asked Questions
The RDA for adults is 900 mcg (0.9 mg) per day. It rises to 1.0 mg during pregnancy and 1.3 mg while breastfeeding. Men and women have the same requirement outside of pregnancy and lactation. The upper limit for adults is 10 mg per day from all sources, including food and multivitamins.
Chelated forms such as copper bisglycinate and copper glycinate are generally considered among the best absorbed and best tolerated. Copper citrate, gluconate, and sulfate are also absorbed reasonably well. Copper oxide is the form to avoid, as very little of it is absorbed. Human trials directly comparing these forms are limited, so tolerability and dose matter as much as form.
Yes. In the United States, copper supplements are sold over the counter as dietary supplements in pharmacies, health stores, and online. No prescription is needed. Because doses vary widely, from under 1 mg to 4 mg per serving, it’s worth checking your total daily intake and speaking with a healthcare provider before starting one.
A blood test measuring serum copper and ceruloplasmin is the most reliable way to find out. Your doctor may order one if you have anemia that isn’t responding to iron, low white blood cell counts, unexplained nerve symptoms, a history of bariatric surgery, or long-term high-dose zinc use. Most people who eat a varied diet get enough copper from food.
Zinc and copper compete for absorption, so long-term zinc use, especially at 50 mg per day or more, can lower copper levels. Many clinicians recommend a small amount of copper for people taking zinc long term. To reduce competition, take them at different times of day, and ask your provider about the right ratio for you.
Most copper supplements are best taken with a meal to reduce the chance of nausea. Some products, like Global Healing Cu1, are labeled for use on an empty stomach. Whichever you choose, take copper a few hours apart from high-dose zinc or iron supplements so they don’t compete for absorption.
People with Wilson’s disease, liver disease, or biliary obstruction should not take copper supplements. Copper can interfere with chelating medications such as penicillamine and trientine. It also competes with zinc and iron for absorption. If you are pregnant, breastfeeding, or taking prescription medication, check with your doctor before starting any copper supplement.
Final Thoughts
Our top pick is Swanson Chelated Copper 2 mg. It uses a branded bisglycinate chelate, keeps the dose at a sensible 2 mg, and costs about four cents per tablet.
If you want the lowest effective dose, Global Healing Bio-Active Copper delivers exactly the RDA. Vegans and budget-focused buyers will be well served by Nutricost Copper Glycinate.
If you have unexplained anemia, nerve symptoms, liver disease, or a history of high-dose zinc use, see your doctor for blood work before choosing any copper supplement.
If you take zinc as part of an eye-health formula, see our guide to the best supplements for eyesight improvement, which covers zinc–copper balance in AREDS 2 formulas.