Best 5 DGL Supplements for Digestive Comfort and Stomach Support

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DGL (deglycyrrhizinated licorice) is a popular herbal option for soothing occasional heartburn, indigestion, and stomach lining irritation. By removing most of the glycyrrhizin found in regular licorice, DGL aims to deliver the gut‑soothing benefits while minimizing the blood‑pressure and potassium concerns associated with whole licorice. This guide explains how DGL works, who it helps, how to choose a high‑quality product, and how to use it safely. We’ll add the Top 8 product picks and a comparison table once you share your shortlist.

Our Top Picks for DGL Supplements

1. Best Overall DGL Supplement: Nutricost DGL Deglycyrrhizinated Licorice Extract Capsules (5,000 mg Equivalent, 120 Servings)

  • Why? Delivers a high-strength 5,000 mg licorice root equivalent per serving in vegan capsules, providing potent digestive support and soothing benefits. Non-GMO, gluten-free, and manufactured in a GMP-compliant facility for quality.
  • Key Benefits: Supports digestive comfort, promotes healthy stomach lining, and aids in soothing the gastrointestinal tract.
  • Best for: Users seeking a powerful, high-quality DGL supplement for daily gut health support.

2. Best Vegan DGL Capsules: NaturesPlus Herbal Actives Licorice (DGL) Capsules – 500 mg, 60 Servings

  • Why? Offers standardized DGL extract in a vegetarian capsule with 500 mg per serving for consistent potency. Free from gluten and allergens, making it ideal for plant-based lifestyles.
  • Key Benefits: Promotes digestive relief, supports mucosal health, and soothes occasional heartburn.
  • Best for: Individuals following a vegan or vegetarian diet looking for clean, plant-based digestive support.

3. Best Multi-Herbal Digestive Blend: Pure Encapsulations DGL Plus – with Marshmallow Root, Aloe Vera, and Slippery Elm Bark

  • Why? Combines DGL with soothing botanicals like marshmallow root, aloe vera extract, and slippery elm bark for enhanced digestive and mucosal support. Non-GMO, hypoallergenic, and vegan-friendly.
  • Key Benefits: Supports gastrointestinal comfort, calms the stomach, and promotes healthy mucosal lining.
  • Best for: Those seeking a synergistic herbal blend for comprehensive gut health and digestive relief.

4. Best Chewable DGL: Nature’s Way DGL Chewable Tablets – 100 Count

  • Why? Convenient chewable format delivers deglycyrrhizinated licorice extract for rapid digestive relief without the need for water. Naturally flavored, gluten-free, and dairy-free.
  • Key Benefits: Supports quick relief from occasional indigestion, heartburn, and upset stomach.
  • Best for: People who prefer a chewable supplement for on-the-go digestive support.

5. Best Alcohol-Free Licorice Liquid: Horbäach Licorice Root Extract – 2 fl oz Tincture

  • Why? Concentrated alcohol-free licorice root extract in liquid form for fast absorption and flexible dosing. Vegetarian, non-GMO, and gluten-free formula.
  • Key Benefits: Supports digestive comfort, respiratory health, and throat soothing.
  • Best for: Users who prefer an alcohol-free liquid supplement for quick and customizable licorice root intake.
RankProductFormPrice per CountHighlightKey BenefitsBest For
1️⃣Nutricost DGL Deglycyrrhizinated Licorice Extract Capsules (5,000 mg Equivalent, 120 Servings)Capsule$0.17Best Overall DGL SupplementDigestive comfort, healthy stomach lining, gastrointestinal soothingUsers seeking a powerful, high-quality DGL supplement for daily gut health
2️⃣NaturesPlus Herbal Actives Licorice (DGL) 500mg (60ct)Capsule$0.33Best Vegan DGL CapsulesDigestive relief, mucosal health, occasional heartburn supportVegan or vegetarian individuals seeking clean, plant-based digestive support
3️⃣Pure Encapsulations DGL Plus (60ct)Capsule$0.78Best Multi-Herbal Digestive BlendGastrointestinal comfort, stomach calming, mucosal lining healthThose seeking a herbal blend with added marshmallow root, aloe vera, and slippery elm
4️⃣Nature’s Way DGL Chewable Tablets (100ct)Chewable Tablet$0.16Best Chewable DGLQuick indigestion relief, heartburn support, upset stomach soothingPeople preferring chewable supplements for on-the-go digestive aid
5️⃣Horbäach Licorice Root Extract (2 fl oz)Liquid$6.00/fl ozBest Alcohol-Free Licorice LiquidDigestive comfort, respiratory support, throat soothingUsers preferring alcohol-free liquid for fast absorption and flexible dosing

1. Best Overall DGL Supplement: Nutricost DGL Deglycyrrhizinated Licorice Extract Capsules (5,000 mg Equivalent, 120 Servings)

4.4 out of 5 (134+) from Amazon
Nutricost DGL Deglycyrrhizinated Licorice Extract Capsules

Price: $13.95

Nutricost’s DGL capsules deliver a high-potency 10:1 extract, providing the equivalent of 5,000 mg of deglycyrrhizinated licorice per serving. Designed for those seeking digestive comfort without the potential side effects of glycyrrhizin, this supplement comes in a vegan, non-GMO capsule form. Each bottle contains 120 servings, making it an affordable and long-lasting choice.

Key Benefits

  • Supports healthy stomach lining and mucosal tissue
  • Provides natural digestive comfort and heartburn relief
  • Convenient capsule form for those avoiding sweeteners in chewable DGL
  • High-strength 10:1 extract for concentrated support
  • Suitable for vegans and made without GMOs

Key Ingredients

  • Deglycyrrhizinated Licorice (Glycyrrhiza glabra) root extract – 500 mg per capsule (10:1 ratio, equivalent to 5,000 mg DGL)
  • Other ingredients: Hypromellose (capsule), magnesium stearate (vegetable source), microcrystalline cellulose

Pros

  • High extract concentration for stronger support
  • No added sweeteners or flavors
  • Vegan and non-GMO
  • Manufactured in an NSF Certified, GMP-compliant facility
  • Third-party tested for purity and potency

Cons

  • Lacks added soothing herbs like aloe or marshmallow root found in some blends
  • Some users may prefer chewable forms for faster coating action

Customer Feedback

  • Value for Money: Many users highlight the affordability compared to other high-potency DGL supplements, especially given the 120-serving supply.
  • Effectiveness: Reports include relief from acid reflux, stomach acid discomfort, and even pancreatic pain in one case. Several users use it as a natural alternative to Tums.
  • Ease of Use: Capsules are preferred by those who dislike the sweetness of chewable DGL. Easy to swallow and without strong aftertaste.
  • Side Effects: No significant adverse effects reported; some note the neutral taste as a plus.

Best Suited For
Individuals seeking high-dose, sugar-free DGL in capsule form for daily digestive health, stomach lining support, or acid reflux relief—especially those avoiding chewable tablets due to taste preferences or added sweeteners.

Usage Recommendations
Take 1 capsule (500 mg) up to three times daily, ideally 15–20 minutes before meals. Follow the manufacturer’s instructions and consult a healthcare provider if using long-term or with other medications.

Summary: Nutricost DGL delivers exceptional potency at a budget-friendly price, with clean, vegan ingredients and rigorous third-party testing. Ideal for anyone who wants maximum digestive support in a convenient capsule form without sweeteners or unnecessary additives.

2. Best Vegan DGL Capsules: NaturesPlus Herbal Actives Licorice (DGL) Capsules – 500 mg, 60 Servings

4.2 out of 5 (656+) from Amazon
NaturesPlus Herbal Actives Licorice (DGL) Capsules

Price: $15.45

NaturesPlus Herbal Actives Licorice (DGL) offers 500 mg of deglycyrrhizinated licorice root per capsule, standardized to contain less than 2% glycyrrhizin (<10 mg). This ensures digestive comfort benefits without the blood pressure risks associated with higher glycyrrhizin levels. The vegan, gluten-free capsules come in a 60-serving bottle, ideal for those seeking a plant-based and allergen-friendly formula.

Key Benefits

  • Helps soothe occasional acid reflux and heartburn
  • Supports the body’s natural stomach and esophageal lining repair
  • Standardized extract with controlled glycyrrhizin content for safety
  • Vegan, vegetarian, and gluten-free formula suitable for sensitive diets
  • Backed by a well-known herbal supplement brand with a long market presence

Key Ingredients

  • Licorice (DGL) (Glycyrrhiza glabra root) – 500 mg per capsule, standardized to <2% glycyrrhizin (<10 mg)
  • Other ingredients: Vegetable cellulose, microcrystalline cellulose, magnesium stearate, silica, di-calcium phosphate

Pros

  • Standardized for consistent potency and safety (<2% glycyrrhizin)
  • Vegan and gluten-free, with no artificial sweeteners
  • Trusted herbal brand with decades of experience
  • Compact 60-capsule supply suitable for short-term trials

Cons

  • Smaller supply (60 servings) compared to competitors with larger bottles
  • Some customers report a bitter taste if capsules are opened
  • Higher cost per capsule than larger-supply brands

Customer Feedback

  • Value for Money: Users find it worth the price for the quality and effectiveness, though some note it’s more expensive per serving than bulk options.
  • Effectiveness: Multiple users report long-term relief from acid reflux, GERD, and even superficial ulcers when combined with dietary changes. Positive outcomes include reduced nighttime burning and improved sleep.
  • Ease of Use: Capsules are convenient, but some open them to mix the powder with saliva for faster relief—though this can cause a temporary bitter taste and teeth discoloration.
  • Side Effects: Generally well-tolerated. One negative review mentioned a change in product taste and formulation, leading to discomfort.

Best Suited For
Those seeking a standardized, plant-based DGL supplement from a reputable herbal brand, especially if they have dietary restrictions like vegan or gluten-free needs and prefer a tightly controlled glycyrrhizin content for safety.

Usage Recommendations
Take 1 capsule before meals or as directed by a healthcare provider. For more intensive support, some users take 2 capsules 15–20 minutes before eating or at bedtime, but always follow label directions and consult your provider if you have ongoing symptoms.

Summary: NaturesPlus Herbal Actives Licorice (DGL) delivers a standardized, vegan, and gluten-free digestive health option with tightly controlled glycyrrhizin content. A trusted choice for those needing safe, gentle, and consistent support against occasional acid reflux and heartburn.

3. Best Multi-Herbal Digestive Blend: Pure Encapsulations DGL Plus – with Marshmallow Root, Aloe Vera, and Slippery Elm Bark

4.4 out of 5 (1322+) from Amazon
Pure Encapsulations DGL Plus

Price: $27.40

Pure Encapsulations DGL Plus combines deglycyrrhizinated licorice with aloe vera extract, slippery elm bark, and marshmallow root, creating a synergistic herbal blend aimed at supporting a healthy stomach lining, soothing the digestive tract, and promoting gut comfort. This vegan, non-GMO, and gluten-free formula is hypoallergenic and free from unnecessary additives, making it a premium option for those with dietary sensitivities. Each capsule provides 60 servings per bottle.

Key Benefits

  • Supports healthy stomach lining and mucosal integrity
  • Provides relief for occasional acid reflux, gastritis, and indigestion
  • Combines DGL with additional soothing herbs for enhanced gut comfort
  • Vegan, non-GMO, gluten-free, and hypoallergenic
  • Free from artificial sweeteners and common allergens

Key Ingredients

  • Deglycyrrhizinated licorice extract (root) – 300 mg
  • Aloe vera extract (inner fillet, standardized to 10% polysaccharides) – 50 mg
  • Slippery elm powder (bark) – 100 mg
  • Marshmallow extract (root) – 200 mg
  • Other ingredients: Vegetarian capsule (cellulose, water), ascorbyl palmitate

Pros

  • Multi-ingredient formula for broader digestive support
  • Clean label with no artificial ingredients or sweeteners
  • Hypoallergenic, vegan, gluten-free, and non-GMO
  • Suitable for those with multiple dietary restrictions
  • Highly rated for ingredient quality and product purity

Cons

  • Higher price per serving compared to single-ingredient DGL supplements
  • Lower DGL content (300 mg) than some stand-alone products
  • Some customers report mild side effects like nausea or changes in blood pressure

Customer Feedback

  • Stomach Comfort: Many users note relief from gastritis, acid reflux, and general stomach discomfort, with improved gastric mucus protection.
  • Effectiveness: Several customers report positive results from the first dose, often saying it works better than acid reducers when combined with diet changes.
  • Gut Health: Users highlight improved digestion and long-term gut health recovery, especially when paired with lifestyle changes.
  • Ingredients: Praised for the absence of sugars and unnecessary additives, making it easier to incorporate into sensitive diets.
  • Taste & Ease of Use: Easy-to-swallow capsules with no aftertaste; considered gentler than chewable DGL options.
  • Side Effects: A small number of customers report increased blood pressure or heart palpitations—likely due to individual sensitivities despite DGL being low in glycyrrhizin.

Best Suited For
Individuals seeking a premium, all-in-one herbal digestive formula that not only includes DGL but also additional botanicals for soothing the stomach and supporting gut health—especially those with food sensitivities or dietary restrictions.

Usage Recommendations
Take 1 capsule daily before a meal or as directed by a healthcare professional. Those with existing health conditions or on medications—especially for blood pressure or heart health—should consult their provider before use.

Summary: Pure Encapsulations DGL Plus stands out for its synergistic blend of DGL, aloe vera, slippery elm, and marshmallow root, delivering comprehensive digestive and gut health support in a clean, hypoallergenic formula. While it comes at a higher cost, it’s ideal for those who want a premium, multi-ingredient option with excellent ingredient purity.

4. Best Chewable DGL: Nature’s Way DGL Chewable Tablets – 100 Count

4.4 out of 5 (2120+) from Amazon
Nature’s Way DGL Chewable Tablets

Price: $15.49

Nature’s Way DGL Chewable Tablets provide 380 mg of deglycyrrhizinated licorice root extract per serving to help soothe occasional digestive discomfort, heartburn, and irritation of the stomach lining. The chewable format is designed to mix with saliva for quicker relief, while the naturally sweetened flavor makes it more pleasant for those sensitive to licorice taste. This product is free from gluten, soy, and dairy, and comes from a trusted herbal supplement brand with rigorous quality testing.

Key Benefits

  • Supports relief from occasional acid reflux, heartburn, and indigestion
  • Helps maintain healthy stomach and intestinal lining
  • Chewable format offers faster absorption and soothing effects
  • Naturally flavored for better palatability
  • Allergen-free formula suitable for sensitive individuals

Key Ingredients

  • Deglycyrrhizinated Licorice Root Extract – 380 mg per 2-tablet serving
  • Other ingredients: Fructose, cellulose, magnesium stearate, silica, natural flavors

Pros

  • Pleasant natural flavor compared to bitter licorice extracts
  • Chewable form offers quick relief without the need for water
  • Allergen-free and vegetarian-friendly
  • From a reputable herbal supplement brand

Cons

  • Contains fructose, which may be unsuitable for those limiting sugar intake
  • Requires multiple tablets per day for sustained relief
  • Some users may still notice a mild licorice aftertaste

Customer Feedback

  • Value for Money: Many customers feel it’s well-priced for the quality and quantity (100 chewable tablets per bottle).
  • Effectiveness: Frequently praised for easing symptoms of GERD, indigestion, and acid reflux, often within minutes.
  • Ease of Use: Highly rated for convenience—easy to chew and carry, no water needed.
  • Side Effects: Very few reports, though a small number of users mentioned mild bloating or sweetness being too strong.

Best Suited For
Individuals looking for a naturally flavored chewable DGL option to manage occasional digestive discomfort, especially those sensitive to gluten, soy, or dairy.

Usage Recommendations
Chew 2 tablets 20 minutes before meals or as directed by a healthcare professional. For best results, allow the tablets to dissolve in the mouth before swallowing.

Summary: Nature’s Way DGL Chewable Tablets offer a pleasant-tasting, allergen-free solution for soothing occasional digestive discomfort. Ideal for those who prefer a natural flavor and quick relief in a portable chewable format.

5. Best Alcohol-Free Licorice Liquid: Horbäach Licorice Root Extract – 2 fl oz Tincture

4.4 out of 5 (4150+) from Amazon
Horbäach Licorice Root Extract

Price: $9.99

Horbäach Licorice Root Extract delivers the benefits of Glycyrrhiza glabra in a concentrated, alcohol-free liquid form for quick absorption. Designed for those who prefer a tincture over capsules or chewables, this supplement supports digestive health, respiratory function, and overall well-being. The liquid format allows for flexible dosing and can be mixed with water or juice for easier intake.

Key Benefits:

  • Supports digestive comfort and healthy stomach function
  • Promotes respiratory health and soothes the throat
  • Alcohol-free formula for gentler use
  • Rapid absorption due to liquid delivery

Key Ingredients:

  • Licorice Root Extract (Glycyrrhiza glabra) – concentrated herbal extract
  • Vegetable glycerin and purified water as base ingredients

Pros:

  • Alcohol-free, suitable for those avoiding alcohol tinctures
  • Vegetarian, non-GMO, and gluten-free
  • Flexible dosing with a dropper for customized intake
  • Can be mixed into beverages for easier consumption

Cons:

  • Strong herbal taste may not appeal to everyone
  • Requires careful measuring for consistent dosage
  • May not be suitable for long-term use without professional guidance due to natural glycyrrhizin content

Customer Feedback:

  • Effectiveness: Many users note improvement in digestion, reduced heartburn, and throat soothing effects.
  • Taste: Some appreciate the natural sweetness, while others find it too strong.
  • Ease of Use: Dropper format is convenient for adjusting serving size.
  • Overall Satisfaction: Well-received for its potency and purity, especially by those avoiding capsules.

Best Suited For:

  • People preferring liquid supplements for faster absorption
  • Those avoiding alcohol-based tinctures
  • Users seeking licorice root for digestive or respiratory wellness

Usage Recommendations:

  • Shake well before use. Take 1-2 mL (approx. 28–56 drops) up to three times daily, mixed with water or juice, following the label’s instructions.

Summary: Horbäach Licorice Root Extract offers a potent, alcohol-free, and vegetarian-friendly way to enjoy the benefits of licorice root. With its flexible dosing and fast-absorbing liquid format, it’s ideal for those who want herbal digestive and respiratory support without capsules or alcohol.

What is DGL and how does it work?

Licorice root contains compounds that act as natural demulcents—soothing agents that coat and calm irritated mucous membranes. DGL is licorice that’s had most glycyrrhizin removed, which helps reduce the risk of raising blood pressure or lowering potassium. The remaining polyphenols and flavonoids support healthy mucus production and a protective stomach lining, which many people find helpful for occasional heartburn and digestive discomfort.

Key benefits people look for

  • Soothes occasional heartburn and indigestion discomfort
  • Supports a healthy, resilient stomach lining
  • Gentle, drug‑free option for sensitive stomachs
  • Chewable formats can act quickly because they mix with saliva to coat tissues
  • Often stacked with other gut‑soothing herbs (aloe, slippery elm, marshmallow) for added comfort

Note: DGL is not a cure or a substitute for medical care. If you have frequent or severe symptoms, talk with your healthcare provider.

Who might consider DGL (and who should be cautious)

  • Good fit for: Adults with occasional heartburn, mild acid sensitivity after meals, or general stomach lining support needs.
  • Use caution or ask your clinician first if: You’re pregnant or nursing, have a history of high blood pressure or low potassium, kidney disease, or take prescription medications (especially diuretics, corticosteroids, digoxin, warfarin, or blood‑pressure meds). DGL removes most glycyrrhizin, but medical oversight is still wise if you have underlying conditions.

How to choose the best DGL supplement

  • Form that fits your routine
    • Chewable tablets: Most popular. Chewing mixes DGL with saliva for a soothing coating effect.
    • Capsules: Convenient and taste‑free; look for clear DGL content per serving.
    • Powders/lozenges: Flexible dosing; check for added sweeteners.
  • Proven “deglycyrrhizinated” claim
    • Look for “DGL” or “deglycyrrhizinated licorice” on the label and a statement that glycyrrhizin has been removed or reduced.
  • Effective dosage transparency
    • Common serving: 350–400 mg DGL per chewable, taken 1–2 tablets up to three times daily. Capsules often provide 400–600 mg per serving. Brands vary—follow each label.
  • Clean, low‑sugar formulas
    • If you’ll take DGL multiple times daily, check total sugars per serving. Some chewables use sugar alcohols (xylitol, sorbitol); note tolerance if you’re sensitive.
  • Add‑on ingredients (optional)
    • Soothing blends may include aloe vera, slippery elm, marshmallow root, or zinc‑carnosine. Choose single‑ingredient DGL if you prefer simplicity.
  • Quality and testing
    • Prefer brands that state GMP compliance and third‑party testing. U.S. manufacturing, allergen disclosure, and transparent customer support are positives.

Suggested dosing and timing (general guidance)

  • Chewables: Commonly 1–2 tablets, 15–20 minutes before meals and at bedtime. Chew thoroughly to activate the demulcent effect.
  • Capsules: Typically 1 serving (often 400–600 mg) 15–20 minutes before meals.
  • Duration: Many people use DGL as needed during more symptomatic periods. If you need it daily for more than a few weeks, check in with your clinician to rule out underlying issues.

Always follow the specific directions on your product’s label.

Safety, side effects, and interactions

  • Usual tolerance: DGL is generally well‑tolerated. Minor stomach upset or changes in bowel habits can occur, especially with sugar alcohols in chewables.
  • Blood pressure and potassium: DGL removes most glycyrrhizin—the component most associated with blood‑pressure and potassium issues in licorice. Even so, people with hypertension, heart, or kidney conditions should consult a clinician before use.
  • Medication timing: To avoid potential absorption interference, consider taking DGL at least 2 hours apart from medications and other supplements.
  • Special populations: If pregnant, nursing, or managing a medical condition, ask your healthcare provider first.

Smart ways to use DGL

  • Pair with habits that reduce heartburn: Smaller meals, not lying down within 3 hours after eating, limiting alcohol, spicy/fatty foods, chocolate, coffee, and late‑night snacks.
  • Track triggers: Note which foods or patterns flare your symptoms and adjust accordingly.
  • Consider gentle stacks: Some people combine DGL with zinc‑carnosine or digestive bitters before meals. Introduce one change at a time so you can see what actually helps.

How we will evaluate the Top 5 (methodology)

When you share your product list, we’ll score each item on:

  • Label accuracy and clear DGL amount per serving
  • Form (chewable vs capsule) and sugar content per daily use
  • Presence of unnecessary additives or allergens
  • Third‑party testing, GMP standards, and brand reputation
  • Real‑world feedback on effectiveness, taste, and ease of use
  • Price per serving and overall value

FAQ

When is the best time to take DGL?

About 15–20 minutes before meals and at bedtime is most common, especially for chewables.

How quickly will I see results?

Chewables can start soothing within minutes; capsules and liquids may take longer to notice effects.

Is DGL safe for long-term use?

Many use it for weeks to months without issues, but consult your doctor for extended use.

Can I take DGL with other digestive medications?

Yes, but space them at least 2 hours apart and check with your healthcare provider for possible interactions.

Final note

DGL is a well‑liked, gentle option for soothing occasional heartburn and supporting the stomach lining.

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