Artichoke extract has long been valued for its remarkable health benefits—especially when it comes to supporting liver function, digestion, and cholesterol balance. While the vegetable itself is delicious and nutritious, the concentrated extract offers a much more potent dose of its key compounds like cynarin and luteolin, which are scientifically recognized for promoting bile flow, detoxification, and heart health.
Whether you’re dealing with occasional bloating, high cholesterol levels, or simply looking to boost your liver’s natural detox capacity, an artichoke supplement can offer a gentle yet effective solution. In this guide, we break down everything you need to know—and we’ve reviewed the top 5 best artichoke extract supplements based on potency, purity, formulation, and real customer results.
Our Top Picks for Artichoke Extract Supplements
1. Best Overall Artichoke Supplement: Nutricost Artichoke Extract 600mg (240 Capsules)
- Why? Delivers 600 mg of standardized artichoke extract per capsule with 5% cynarin. Offers 240 servings per bottle, non-GMO, gluten-free, vegetarian, and third-party tested by ISO-accredited labs—making it a reliable, cost-effective, and high-quality choice.
- Key Benefits: Supports liver function, bile production, and digestive health.
- Best for: Long-term users who want a large, affordable supply of a standardized and lab-tested supplement.
2. Best Value High-Potency Extract: Zazzee Extra Strength Artichoke 9000 mg (150 Capsules)
- Why? Provides a potent 20:1 extract with 9000 mg equivalent strength per capsule and 5% caffeoylquinic acid. Vegan, non-GMO, and allergen-free formula at a competitive price for 5 months’ supply.
- Key Benefits: Promotes liver detox, bile production, and digestive wellness.
- Best for: Budget-conscious users seeking high potency and clean ingredient sourcing.
3. Best for Standardized Cynarin Content: Toniiq Artichoke Extract 1200mg (120 Capsules)
- Why? Delivers 1200 mg of 15:1 artichoke extract with a high concentration of 5% cynarin (60 mg per serving). Each batch is both in-house and third-party lab tested for purity and active compound levels.
- Key Benefits: Boosts liver detoxification, supports healthy cholesterol, and improves digestion.
- Best for: Users who prioritize clinical-standard quality and verified ingredient potency.
4. Best for Trusted Brand & Long-Term Use: Jarrow Formulas Artichoke 500mg (180 Capsules)
- Why? Offers 180 capsules with standardized 5% caffeoylquinic acids per 500 mg dose. Jarrow is a trusted brand known for consistency, and the supplement supports bile production and nutrient absorption.
- Key Benefits: Enhances fat digestion, liver enzyme balance, and overall digestive health.
- Best for: Those seeking long-term support from a reliable brand with strong customer loyalty.
5. Best Gentle Formula for Beginners: Vital Peak Artichoke Extract 500mg (30 Capsules)
- Why? Delivers 500 mg of whole-herb extract with 5% cynarin in a clean, vegan, and allergen-free formula. Manufactured in the USA without gluten, soy, or dairy.
- Key Benefits: Supports liver detox, digestive comfort, and energy metabolism.
- Best for: New users or those with sensitivities looking for a short-term, clean-label liver support supplement.
| Rank | Product | Form | Price per Count | Highlight | Key Benefits | Best For |
|---|---|---|---|---|---|---|
| 1️⃣ | Nutricost Artichoke Extract 600mg (240ct) | Capsule | $0.08 | Best Overall Artichoke Supplement | Supports liver function, bile production, and digestive health | Long-term users wanting a large, affordable, lab-tested supplement |
| 2️⃣ | Zazzee Extra Strength Artichoke 9000mg (150ct) | Capsule | $0.11 | Best Value High-Potency Extract | Promotes liver detox, bile production, and digestive wellness | Budget-conscious users seeking high potency and clean ingredient sourcing |
| 3️⃣ | Toniiq Artichoke Extract 1200mg (120ct) | Capsule | $0.11 | Best for Standardized Cynarin Content | Boosts liver detoxification, supports healthy cholesterol, and improves digestion | Users prioritizing clinical-standard quality and verified ingredient potency |
| 4️⃣ | Jarrow Formulas Artichoke 500mg (180ct) | Capsule | $0.13 | Best for Trusted Brand & Long-Term Use | Enhances fat digestion, liver enzyme balance, and overall digestive health | Those seeking long-term support from a reliable, established brand |
| 5️⃣ | Vital Peak Artichoke Extract 500mg (30ct) | Capsule | $0.67 | Best Gentle Formula for Beginners | Supports liver detox, digestive comfort, and energy metabolism | New users or those with sensitivities seeking short-term, clean-label support |
1. Best Overall Artichoke Supplement: Nutricost Artichoke Extract 600mg (240 Capsules)
Price: $16.95
Nutricost’s Artichoke Extract offers a simple, high-potency formula that delivers 600mg of artichoke extract per capsule, standardized to 5% cynarin. Each bottle contains a generous 240 capsules—making it ideal for long-term use at an affordable cost. It’s non-GMO, gluten-free, vegetarian-friendly, and 3rd-party tested, reflecting Nutricost’s commitment to clean and reliable supplements.
Key Benefits
- Supports healthy liver detox and bile production
- Aids digestion and helps reduce bloating
- May help regulate cholesterol levels
- Provides antioxidant protection
- Delivers long-lasting supply with 240 servings per bottle
What it Contains
- Artichoke Extract (Cynara scolymus L.) – 600mg per capsule, standardized to 5% cynarin
- Form: Vegetarian capsule
- Other Ingredients: Hypromellose, rice flour, magnesium stearate (vegetable), silica
- Serving Size: 1 capsule daily
Pros
- High potency per capsule (600mg)
- Excellent price-per-count ($0.07)
- 240 full servings per bottle
- Non-GMO, gluten-free, vegetarian formula
- Third-party tested for purity and safety
Cons
- Does not include additional liver-supporting herbs
- No timed-release option for gradual absorption
Customer Feedback:
- Value for Money: Users widely praise its affordability, calling it a “good value” and “worth it,” especially for the high capsule count.
- Effectiveness: Many report subtle yet noticeable improvements in digestion, energy, and general well-being after a few weeks.
- Ease of Use: One capsule a day is convenient and easy to add to a daily routine.
- Functionality: Customers find the product works as expected with no aftertaste or side effects.
Best Suited For
- Budget-conscious users seeking long-term liver and digestive support
- Those who prefer simple, single-ingredient formulas
- Individuals managing cholesterol or bile production naturally
Usage Recommendations
Take 1 capsule daily, preferably with a meal to support digestion and absorption. Consistent daily use may yield better results for liver and cholesterol health.
Summary: Nutricost Artichoke Extract offers high potency and outstanding value, making it an ideal choice for anyone seeking liver and digestive support on a budget. With 240 capsules per bottle, it’s perfect for consistent, long-term use without breaking the bank.
2. Best Value High-Potency Extract: Zazzee Extra Strength Artichoke 9000 mg (150 Capsules)
Price: $19.97
Zazzee’s Extra Strength Artichoke Extract delivers one of the most concentrated formulas on the market. Each capsule provides 450mg of a 20:1 extract, equivalent to 9000mg of raw artichoke leaf, standardized to 5% caffeoylquinic acid—the compound responsible for its liver and digestive benefits. Made in the USA, this supplement is 100% vegan, non-GMO, gluten-free, and free from major allergens.
Key Benefits
- Promotes liver detox and supports normal liver enzyme levels
- Enhances digestion and bile production
- May assist with weight support and metabolic function
- Standardized to 5% caffeoylquinic acid for maximum potency
- Offers a full 5-month supply in one bottle
What it Contains
- Artichoke Extract (20:1) – 450mg per capsule (equivalent to 9000mg of raw leaf)
- Standardized to 5% caffeoylquinic acid
- Form: Vegan capsule
- Other Ingredients: Rice powder, cellulose, silica, magnesium stearate (vegetable)
- Serving Size: 1 capsule per day
Pros
- Ultra-concentrated 20:1 extract
- Standardized to a high 5% caffeoylquinic acid
- Vegan, non-GMO, gluten-free, no common allergens
- Manufactured in the USA in GMP-certified facilities
- Excellent customer satisfaction for liver health and digestion
Cons
- Slightly higher price per capsule ($0.13) compared to basic formulas
- Not ideal for those who prefer whole herb over concentrated extracts
Customer Feedback:
- Liver Health: Highly rated for liver support—many users report improved liver lab results and overall liver function.
- Value for Money: Customers feel the product offers great potency and quality for the price.
- Digestive Support: Multiple users report improved digestion and easier bowel movements.
- Product Quality: Users appreciate the strong concentration, clean formula, and U.S. manufacturing standards.
Best Suited For
- Individuals with liver enzyme concerns or looking for strong liver detox support
- Those wanting a more concentrated extract with clinical-standard potency
- Health-conscious users who prefer vegan, allergen-free formulas
Usage Recommendations
Take 1 capsule daily with a meal. Because this is a concentrated extract, sticking to the recommended dose is advised. For best results, pair with a healthy diet and adequate hydration.
Summary: Zazzee Extra Strength Artichoke Extract delivers a highly potent 9000mg equivalent dose with 5% caffeoylquinic acid, making it an ideal choice for those looking for maximum liver and digestive support. It stands out for its clean label, U.S. manufacturing, and strong customer reviews on quality and results.
3. Best for Standardized Cynarin Content: Toniiq Artichoke Extract 1200mg (120 Capsules)
Price: $14.97
Toniiq is known for premium-quality herbal extracts, and their Artichoke Extract is no exception. This supplement provides a high-strength 15:1 extract with a verified 5% cynarin content—ensuring optimal bioactive potency for liver and digestive support. Each batch is rigorously tested in both in-house and third-party labs to verify purity, potency, and safety. With 1,200mg per serving, it’s designed for those who prioritize both strength and lab-verified integrity.
Key Benefits
- High concentration of cynarin for liver and bile flow support
- Aids healthy digestion and cholesterol regulation
- Thoroughly lab-tested for purity, potency, and contaminants
- May support fat metabolism and detoxification
- Easy-to-swallow vegetarian capsules
What it Contains
- Artichoke Leaf Extract (15:1) – 1,200mg per serving (2 capsules)
- Standardized to 5% Cynarin (60mg)
- Form: Vegetarian capsule
- Other Ingredients: Hydroxypropyl methylcellulose, microcrystalline cellulose, vegetable magnesium stearate, silicon dioxide
- Serving Size: 2 capsules daily with a meal
Pros
- Ultra-concentrated 15:1 extract with a high 5% cynarin content
- Verified by third-party and in-house lab testing
- Clean label with no unnecessary fillers
- Made in a GMP-certified USA facility
- Positive feedback for cholesterol and digestion support
Cons
- Some complaints about capsule quality (loose powder, inconsistent fill)
- Slightly higher dose required (2 capsules per serving)
- Mixed user experience—some users did not notice major effects
Customer Feedback:
- Effectiveness: Some users feel noticeable support for digestion and cholesterol. A few mentioned subtle effects while others noted no significant change.
- Ease of Use: Capsules are easy to swallow and digest well for most users.
- Product Quality: Mixed reviews—many praised the concentration and results, while a few highlighted poor capsule integrity or uneven powder distribution.
- Side Effects: Generally well-tolerated, although one review mentioned mild sleep disturbances from possible overdosing.
Best Suited For
- Users focused on verified purity and high cynarin content
- Individuals seeking high-strength artichoke extract in capsule form
- People looking to support liver detox, fat metabolism, and cholesterol naturally
Usage Recommendations
Take 2 capsules daily with food, preferably in the morning or midday. Avoid taking too close to bedtime if sensitive to bile stimulation. For best results, monitor consistency and pair with a liver-friendly diet.
Summary: Toniiq Artichoke Extract stands out for its ultra-pure, lab-tested formulation and 5% cynarin content—ideal for users who prioritize potency and manufacturing transparency. However, inconsistent capsule quality is worth noting for some buyers.
4. Best for Trusted Brand & Long-Term Use: Jarrow Formulas Artichoke 500mg (180 Capsules)
Price: $23.95
Jarrow Formulas is a trusted U.S. supplement brand known for its science-backed formulations. This vegan-friendly artichoke supplement delivers 500 mg of standardized leaf extract with 5% caffeoylquinic acids per capsule. With 180 servings per bottle, it offers a full 6-month supply—ideal for those looking for consistent support for liver health, bile production, and fat digestion.
Key Benefits
- Supports bile production and fat metabolism
- Promotes cholesterol balance and liver detox
- Helps improve nutrient absorption from fat-soluble vitamins
- Offers a long-lasting supply (180 servings)
- Gentle on digestion and easy to swallow for most
What it Contains
- Artichoke Extract (Cynara scolymus Leaf) – 500 mg per capsule
- Standardized to 5% Caffeoylquinic Acids (25 mg)
- Form: Veggie capsule
- Other Ingredients: Microcrystalline cellulose, hydroxypropylmethylcellulose, maltodextrin, magnesium stearate (vegetable source), silicon dioxide
- Serving Size: 1 capsule daily with food
Pros
- One of the most well-reviewed artichoke supplements on the market
- Great for long-term use and daily liver maintenance
- High customer satisfaction across quality, effectiveness, and pain relief
- Excellent value at $0.13 per serving
- Non-GMO, gluten-free, and vegan-friendly
Cons
- Contains maltodextrin, which some users dislike due to glycemic concerns
- Mixed opinions on capsule size—some find them too large
- May take 1–2 months of consistent use to feel noticeable results
Customer Feedback:
- Cholesterol Support: Many users report improved LDL and liver enzyme levels, especially with long-term use.
- Effectiveness: Several reviews confirm improved bile flow, gallbladder comfort, and digestion. Some mention relief from aches and pains.
- Ease of Swallowing: Generally easy to swallow, though a few reviews note the capsule is on the larger side.
- Value for Money: Excellent value with 180 capsules per bottle and a competitive price.
- Quality Concerns: Trusted brand with minimal complaints about consistency or manufacturing, but additives like maltodextrin were mentioned by a few.
Best Suited For
- Individuals seeking sustained support for liver and gallbladder health
- People who want a reliable, long-term supplement from a reputable brand
- Anyone needing help with cholesterol, digestion, and bile production
Usage Recommendations
Take 1 capsule daily with food. For those addressing bile flow or cholesterol issues, consistency over several weeks is key. Consult your healthcare provider if you have gallbladder conditions.
Summary: Jarrow Formulas Artichoke is a go-to choice for long-term liver and cholesterol support. Backed by strong customer loyalty, it’s affordable, well-tolerated, and ideal for consistent daily use—just be mindful of the maltodextrin if you’re sensitive to additives.
5. Best Gentle Formula for Beginners: Vital Peak Artichoke Extract 500mg (30 Capsules)
Price: $19.99
Vital Peak’s Artichoke Extract delivers a clean and allergen-free 500 mg dose of artichoke leaf extract per capsule. Designed to support liver function and digestive comfort, this supplement is manufactured in the USA and marketed as gluten-free, vegan, and free of soy and dairy. It comes in a 30-capsule bottle, making it ideal for short-term use or first-time users.
Key Benefits
- Supports liver enzyme function and detoxification
- Aids digestion and bile production
- May help reduce bloating and improve nutrient absorption
- Potential benefits for energy and mental clarity
- Suitable for those with common dietary restrictions (vegan, gluten-free, dairy-free)
Key Ingredients
- Artichoke Extract (Cynara scolymus) – 500 mg, standardized to 5% Cynarin
- Other ingredients: Hypromellose (capsule), Microcrystalline Cellulose, L-Leucine, Magnesium Stearate, Olive Oil, Silicon Dioxide
- Form: Vegetarian capsule
- Dosage: 1 capsule daily
Pros
- Clean label with minimal additives
- Allergen-free (no soy, dairy, or gluten)
- Made in the USA
- Easy to swallow gel capsules
- Suitable for sensitive users
Cons
- Higher cost per capsule compared to alternatives ($0.67/count)
- Lacks third-party testing or GMP certification
- Only 30 capsules per bottle (1-month supply)
Customer Feedback:
Value for Money:
Many users feel the price is on the higher side, especially for only a 30-day supply. However, they appreciate the allergen-free formula and simplicity of ingredients.
Effectiveness:
Users noted improved digestion, better sleep, and more energy within a few weeks. However, several mentioned that long-term liver benefits would need more time to assess.
Ease of Use:
The capsules are well-reviewed for being easy to swallow, with no aftertaste. Customers liked the gel cap format.
Purity and Safety:
Customers praised the lack of unnecessary fillers and the simple, focused formula. One downside mentioned was the absence of third-party testing confirmation.
Best Suited For
This supplement is best for individuals seeking a gentle and allergen-free short-term boost for liver and digestive health, especially those on vegan or gluten-free diets.
Usage Recommendations
Take 1 capsule per day with food. Ideal for a one-month trial, especially if you’re evaluating your response to artichoke extract before committing to a larger bottle.
Summary: Vital Peak Artichoke Extract is a clean, vegan-friendly choice for digestive and liver support. While priced higher per serving, it appeals to health-conscious users seeking a filler-free, allergen-free formula with short-term benefits.
Benefits of Artichoke Extract Supplements
Artichoke extract is much more than a digestive aid—it’s a powerful botanical known for its antioxidant and hepatoprotective effects. Here are the main benefits supported by both tradition and research:
- Liver Health Support: Cynarin in artichoke extract promotes bile production, helping the liver break down fats and flush out toxins more efficiently.
- Improved Digestion: It may relieve symptoms like bloating, indigestion, and gas by enhancing bile flow and supporting gallbladder function.
- Cholesterol Management: Some studies suggest that artichoke extract can help reduce LDL cholesterol and triglycerides while boosting HDL cholesterol.
- Antioxidant Protection: Artichokes are rich in polyphenols like luteolin, which help combat oxidative stress and support cellular health.
- Metabolism Boost: By supporting liver function and fat processing, artichoke extract may play a role in healthy weight management.
How We Selected the Best Artichoke Supplements
To identify the best artichoke supplements on the market, we evaluated products using the following criteria:
- Cynarin Content: We prioritized supplements with standardized extracts that list cynarin or globe artichoke leaf extract with clear dosage per serving.
- Clean Formulations: No unnecessary fillers, additives, or artificial ingredients.
- Third-Party Testing: Products backed by quality certifications or lab-tested for purity and potency.
- Dosage & Delivery Form: Effective dosages in user-friendly formats (e.g., capsules, softgels, or tinctures).
- Customer Feedback: We analyzed real customer experiences on Amazon and other platforms to gauge satisfaction, effectiveness, and side effects.
Artichoke Extract Buying Guide
Before picking a supplement, here are a few key factors to consider:
- Standardized vs. Raw Extract: Standardized artichoke extract (usually to cynarin content) ensures consistency and potency. Raw or whole herb powders may be less reliable in terms of therapeutic effects.
- Form of Supplement: Capsules are the most popular, but some prefer liquid extracts for faster absorption or powders for flexible dosing.
- Synergistic Ingredients: Some formulas include milk thistle, dandelion root, or turmeric for enhanced liver detox support.
- Daily Dosage: Look for products that provide at least 300 mg of artichoke extract per serving to match most clinical research levels.
FAQs About Artichoke Extract Supplements
When is the best time to take artichoke extract?
Most people take it before meals to support digestion, but it can also be taken once or twice daily for general liver support.
Can I take artichoke extract long-term?
Yes, artichoke extract is generally safe for long-term use if taken as directed. However, consult your healthcare provider if you have gallstones or bile duct obstruction.
How long does it take to notice benefits?
Many users report digestive relief within a few days, while cholesterol and liver function support may take a few weeks.
Does artichoke extract have any side effects?
It’s well-tolerated by most people. Some may experience mild gas or an increase in bowel movements initially.
Can I take it with other liver support supplements?
Yes, artichoke often pairs well with milk thistle, dandelion, turmeric, and NAC. However, avoid stacking too many detox ingredients without professional guidance.
Final Verdict
Artichoke extract is a time-tested herbal solution that supports liver detoxification, improves digestion, and may help maintain healthy cholesterol levels. Choosing the right supplement comes down to potency, purity, and formulation quality.