Best 6 Astragalus Supplements for Immune Support and Vitality (2025)

We may receive commissions if you end up purchasing through links on our site (at no additional cost to you). The revenue helps fund all the free content on the site. Find out more

Astragalus is one of the most respected herbs in Traditional Chinese Medicine, known for its ability to support immune health, fight fatigue, and promote cellular longevity. Today, modern supplements harness the power of Astragalus root in convenient capsules, powders, and liquid extracts—making it easier than ever for Americans to support their wellness goals.

Whether you’re looking to boost your immune defenses, fight everyday stress, or invest in long-term vitality, this guide will help you choose the best Astragalus supplement based on quality, potency, and value.

Our Top Picks for Astragalus Supplements

1. Best Overall Astragalus Supplement: Zazzee Extra Strength Astragalus Root 20:1 Extract 5000mg (180 Capsules)

  • Why? Delivers a powerful 20:1 extract with 5000 mg strength per capsule, standardized to 70% polysaccharides. Offers exceptional potency and purity at an excellent price, with a full 6-month supply.
  • Key Benefits: Enhances immune defense, supports healthy aging, and provides antioxidant protection.
  • Best for: Individuals seeking maximum potency, purity, and long-term value in capsule form.

2. Best Immune Defense Support: Double Wood Astragalus 500mg (180 Capsules)

  • Why? Rich in flavonoids and polysaccharides, this formula is designed to support T-cell activation and overall immune resilience. Third-party tested and affordably priced.
  • Key Benefits: Strengthens immunity, supports heart health, and healthy aging.
  • Best for: Those who want science-backed immune support from a trusted U.S. supplement brand.

3. Best Organic Astragalus Powder: Nutricost Organic Astragalus Root Powder 1lb

  • Why? Offers a full pound of pure organic astragalus powder, ideal for customizing your own dosages in smoothies or teas. Non-GMO and made in a GMP facility.
  • Key Benefits: Traditional herbal support for immunity, kidney health, and vitality.
  • Best for: Users who prefer a pure, unprocessed powder form for versatile use.

4. Best Polysaccharide Concentration: Toniiq Astragalus 600mg 20:1 Extract (120 Capsules)

  • Why? Highly concentrated extract with 70% polysaccharides, each serving delivers 420mg of bioactive compounds. Ethically sourced and third-party tested for potency and purity.
  • Key Benefits: Supports immune system, longevity, and cellular repair.
  • Best for: Users focused on getting a high concentration of bioactive polysaccharides in capsule form.

5. Best Budget-Friendly Astragalus Capsules: Nutricost Astragalus Root 550mg (240 Capsules)

  • Why? Offers 240 servings at just $0.06 per capsule, providing great value for a clean, simple formula. Non-GMO, gluten-free, and tested for quality.
  • Key Benefits: Daily immune support and general wellness.
  • Best for: Budget-conscious buyers looking for a reliable daily astragalus supplement.

6. Best Liquid Astragalus Tincture: MaryRuth Organics Astragalus Root Drops (1 fl oz)

  • Why? USDA Organic, alcohol-free liquid extract providing 1,180 mg per mL. Pleasant-tasting and rapidly absorbed, ideal for users who avoid pills.
  • Key Benefits: Supports immunity, cognitive focus, and energy during stress.
  • Best for: Individuals preferring fast-absorbing, easy-to-take herbal tinctures with clean, vegan ingredients.
RankProductFormPrice per CountHighlightKey BenefitsBest For
1️⃣Zazzee Extra Strength Astragalus Root 20:1 Extract (180ct)Capsule$0.10Best Overall Astragalus SupplementHigh polysaccharide extract, immune and antioxidant supportUsers seeking high potency and long-term value in capsules
2️⃣Double Wood Astragalus 500mg (180ct)Capsule$0.05Best Immune Defense SupportT-cell activation, immune and heart health supportUsers needing science-backed immune support
3️⃣Nutricost Organic Astragalus Root Powder 1lbPowder$1.18/ozBest Organic Astragalus PowderFlexible use in smoothies/teas, immune and vitality supportUsers preferring pure powder form for flexible use
4️⃣Toniiq Astragalus 600mg 20:1 Extract (120ct)CapsuleN/A (Unavailable)Best Polysaccharide ConcentrationConcentrated polysaccharides, cellular repair and immunityUsers focused on bioactive polysaccharides
5️⃣Nutricost Astragalus Root 550mg (240ct)Capsule$0.06Best Budget-Friendly Astragalus CapsulesDaily immune support, clean formula, budget-friendlyBudget-conscious buyers needing daily immune support
6️⃣MaryRuth Organics Astragalus Root Drops (1 fl oz)Liquid$13.45/fl ozBest Liquid Astragalus TinctureFast absorption, immune support, cognitive and stress balanceThose who avoid pills and prefer liquid herbal drops

1. Best Overall Astragalus Supplement: Zazzee Extra Strength Astragalus Root 20:1 Extract 5000mg (180 Capsules)

4.6 out of 5 (895+) from Amazon

Price: $17.77

Zazzee Extra Strength Astragalus offers an impressive 5000 mg strength per capsule using a concentrated 20:1 extract. With 180 vegan capsules per bottle, it provides a 6-month supply—ideal for anyone looking to support their immune system and energy levels daily. It’s standardized to 70% polysaccharides, the most bioactive compounds in Astragalus.

Key Benefits

  • Supports healthy immune function and reduces susceptibility to illness
  • Promotes better energy, vitality, and recovery from fatigue
  • May enhance sleep quality and support respiratory health
  • Helps modulate inflammation and oxidative stress
  • Gentle adaptogen for daily stress and aging support

What It Contains

  • 250 mg Astragalus membranaceus root extract per capsule
  • Standardized to 70% polysaccharides
  • 20:1 extract ratio (equivalent to 5000 mg raw root powder)
  • 180 vegan capsules per bottle
  • Free from gluten, soy, dairy, shellfish, wheat, sweeteners, and additives

Pros

  • High-potency extract with superior bioavailability
  • Large quantity (6-month supply) at a very low cost per dose
  • 100% vegan, non-GMO, and lab-tested
  • Made in the USA in a certified GMP facility
  • No fillers or artificial ingredients

Cons

  • Capsule contains 250 mg of extract—not raw herb—so may be misunderstood by some shoppers
  • No added synergistic herbs (pure Astragalus only)

Customer Feedback

  • Effectiveness:
    Users consistently praise its potency and results, with many noting stronger immunity and general wellness. Some use it as part of their maintenance routine to stay healthy through seasonal changes.
  • Immune System Support:
    Multiple reviews report noticeable improvements in immune strength—some even giving it to their pets for immune support. One noted, “No ill effects. Boosts immune system.”
  • Value for Money:
    Highly rated for affordability. Customers call it “a great value” and appreciate the quality at a fair price, especially for long-term use.
  • Ease of Swallowing:
    The capsules are small and easy to take, with no reported digestive issues or bad aftertaste.
  • Sleep Quality:
    Some reviewers noticed improved sleep and reduced nasal congestion, saying they “sleep a little better” and “feel better overall.”

Best Suited For
Those seeking long-term immune support, anti-aging benefits, or recovery from fatigue and stress. Also a great option for budget-conscious users looking for a pure, high-potency Astragalus extract.

Usage Recommendations
Take 1 capsule daily with food, preferably in the morning. For stronger immune support, some users take up to 2–3 capsules spaced throughout the day. Best used consistently for 4–6 weeks for full benefits.

Summary: Zazzee’s Extra Strength Astragalus delivers unmatched value and potency in one of the cleanest formulas available. With 5000 mg strength, 70% polysaccharides, and 180 vegan capsules, it’s a reliable and cost-effective choice for daily immune, energy, and anti-aging support.

2. Best Immune Defense Support: Double Wood Astragalus 500mg (180 Capsules)

4.6 out of 5 (1314+) from Amazon
Double Wood Astragalus 500mg

Price: $16.95

Double Wood Supplements offers a clean and affordable Astragalus extract designed to support immune health, energy, and longevity. Each 2-capsule serving delivers 500 mg of 4:1 extract, equal to 2000 mg of raw Astragalus root. The bottle includes 180 veggie capsules—enough for a 90-day supply—making it a strong contender for long-term use.

Key Benefits

  • Supports T-cell activation and immune defense
  • Promotes increased energy levels and recovery
  • May help protect telomeres and promote healthy aging
  • Rich in polysaccharides and flavonoids for antioxidant benefits
  • Suitable for stacking with other immune-boosting herbs

What It Contains

  • 500 mg Astragalus root extract (4:1) per 2-capsule serving
  • Equivalent to 2000 mg of raw Astragalus root
  • 180 veggie capsules (90 servings)
  • Gluten-free, Non-GMO, third-party tested
  • Manufactured in a GMP-certified facility in the USA

Pros

  • Affordable cost per serving (~$0.05)
  • Positive feedback on immune, energy, and sleep benefits
  • Free of allergens and unnecessary fillers
  • Sourced and tested for purity and safety
  • Trusted brand with a clean supplement label

Cons

  • Lower extract concentration compared to higher 20:1 products
  • Requires 2 capsules per serving
  • Not standardized to specific polysaccharide %

Customer Feedback

  • Quality:
    Customers are highly satisfied with the overall quality. Many note it pairs well with Vitamin C and other immune-supporting ingredients. Some appreciate that it combines well with Echinacea and ginseng.
  • Value for Money:
    Frequently praised as a great value product, with users citing low cost, high capsule count, and consistent effects.
  • Taste & Ease of Use:
    The capsules are described as easy to swallow with no unpleasant taste or aftereffects—ideal for daily use.
  • Energy Levels:
    Many reviewers experienced noticeable improvements in energy, especially when recovering from stress or workouts.
  • Telomere & Longevity Effects:
    Several users mentioned perceived anti-aging benefits like better physical fitness and improved telomere support.
  • Immune Support:
    Some users reported fewer colds and respiratory infections, even during seasonal illness spikes.

Best Suited For
Adults looking to boost immunity, energy, and healthy aging on a budget. Also great for those who prefer simple formulations and value long-term affordability.

Usage Recommendations
Take 2 capsules daily with meals. For immune support, consistency is key—results may appear within 2–4 weeks of daily use.

Summary: Double Wood Astragalus is a budget-friendly immune and energy support supplement with solid quality, clean ingredients, and positive customer feedback. With 500 mg of 4:1 extract per serving, it’s ideal for daily use and longevity support without breaking the bank.

3. Best Organic Astragalus Powder: Nutricost Organic Astragalus Root Powder 1lb

4.5 out of 5 (404+) from Amazon
Nutricost Organic Astragalus Root Powder 1lb

Price: $19.95

Nutricost’s Organic Astragalus Root Powder offers a USDA-certified organic, unflavored powder form of Astragalus—ideal for those who prefer whole-food, DIY options over capsules. Each serving provides 1000 mg of pure root powder with no fillers or added ingredients. With 454 servings per container, this 1-pound tub delivers unmatched quantity and flexibility at an affordable price.

Key Benefits

  • Offers natural immune support and adaptogenic benefits
  • May aid in liver health, detox, and stress resilience
  • Flexible use in smoothies, teas, or homemade capsules
  • Helps support healthy aging and energy levels
  • Great option for large families, bulk users, or custom dosing

What It Contains

  • 1000 mg organic Astragalus root powder (per 1g scoop)
  • 454 servings per container
  • Certified USDA Organic and CCOF
  • No other ingredients, fillers, or additives
  • Made in a GMP-compliant, FDA-registered facility

Pros

  • Exceptional value for bulk quantity (over 450 servings)
  • 100% pure organic root powder – nothing else added
  • Great for those who want to make their own capsules or teas
  • Mixes well in drinks and smoothies
  • Non-GMO, gluten-free, and vegetarian-friendly

Cons

  • Earthy taste may not be pleasant for everyone
  • Lacks extract concentration (not standardized)
  • Some variability in texture, color, and flavor between batches

Customer Feedback

  • Quality:
    Most reviews mention the powder’s fine texture and light, natural scent, with some noting it helped liver function or general health. A few customers expressed concern over inconsistent quality or off flavors in specific batches.
  • Value for Money:
    Praised for being a great deal, especially for bulk users who make their own capsules or use it in cooking or smoothies. Users highlight its long-lasting supply and cost-saving potential.
  • Health Benefits:
    Customers report improvements in liver health, immune function, and general vitality. Some noted they felt better energy and improved wellness after consistent use.
  • Ease of Use:
    Many reviews mention it mixes smoothly in drinks, doesn’t clump, and is easy to encapsulate. It’s favored by those who enjoy customizing their own herbal blends.
  • Taste & Color:
    Opinions are mixed. Some users love the nutty, natural taste, while others describe it as bitter, grassy, or sawdust-like. A few concerns were raised about color variation or potential rancidity in later batches.

Best Suited For
Health-conscious individuals who want to use Astragalus in a flexible, organic, whole-root form. Ideal for those making smoothies, herbal blends, or who prefer full-spectrum powder over concentrated extracts.

Usage Recommendations
Take 1 scoop (1g) per day mixed into tea, smoothies, or food. It can also be encapsulated for easier consumption. Best taken consistently to build up adaptogenic effects.

Summary: Nutricost Organic Astragalus Root Powder is a top choice for purity, flexibility, and bulk value. With USDA Organic certification and over 450 servings per container, it’s perfect for DIY users looking for an unprocessed, budget-friendly form of Astragalus.

4. Best Polysaccharide Concentration: Toniiq Astragalus 600mg 20:1 Extract (120 Capsules)

4.5 out of 5 (690+) from Amazon
Toniiq Astragalus 600mg 20:1 Extract

Price: Price not available

Toniiq’s Ultra-Concentrated Astragalus capsules offer a premium-grade 20:1 root extract, standardized to a high 70% polysaccharide content. Designed for those seeking maximum immune support and cellular longevity, each bottle contains 120 vegetarian capsules manufactured in a GMP-certified facility in the USA.

Key Benefits

  • Delivers 600 mg of highly concentrated 20:1 extract per capsule (equal to 12,000 mg of raw root)
  • Standardized to 70% polysaccharides, key compounds for immune and anti-aging support
  • Supports immune defense, energy, and cellular function
  • May help improve sleep and promote longevity
  • Third-party lab tested for purity and potency

Key Ingredients

  • Astragalus membranaceus root extract (20:1) – 600 mg per capsule
    • Standardized to ≥70% polysaccharides for maximum efficacy
  • Other Ingredients: Vegetable capsule (hydroxypropyl methylcellulose), vegetable cellulose, vegetable magnesium stearate, silicon dioxide

Pros

  • One of the highest polysaccharide concentrations on the market
  • Lab-tested for purity and potency
  • Vegan and free from common allergens
  • Highly rated for immune support and energy boost

Cons

  • Currently unavailable on Amazon
  • Premium formulation may cost more per capsule compared to basic powders

Customer Feedback

  • Quality: Customers consistently describe Toniiq as a “quality supplement,” outperforming other brands and delivering clean, effective results.
  • Immune System Boost: Many users report fewer colds and improved allergy resilience.
  • Sleep Quality: Reviewers note more restful sleep and better relaxation.
  • Energy Levels: Multiple reports mention a noticeable increase in energy and reduced fatigue.
  • Value for Money: Users appreciate the affordability relative to its high potency and purity.
  • Ease of Swallow & Use: Capsules are easy to take, and the sleek jar design adds convenience.
  • Dosage: Users like the flexible dosing (1–2 capsules/day) and high extract concentration.

Best Suited For

  • Adults seeking strong immune defense, anti-aging support, and energy enhancement
  • Individuals needing standardized polysaccharides for targeted benefits
  • Those preferring highly potent, lab-tested capsules over raw powders

Usage Recommendations
Take 1 capsule once or twice daily with food, or as directed by a healthcare professional. Best taken consistently for long-term immune and wellness benefits.

Summary: Toniiq Astragalus offers one of the most potent polysaccharide concentrations available, ideal for immune support, energy, and aging well. A premium, lab-tested choice for those who value purity and results.

5. Best Budget-Friendly Astragalus Capsules: Nutricost Astragalus Root 550mg (240 Capsules)

4.7 out of 5 (460+) from Amazon
Nutricost Astragalus Root 550mg

Price: $14.95

Nutricost Astragalus Root offers a no-frills, affordable supplement designed for users who want straightforward immune support without the high price tag. Each bottle contains 240 vegetarian capsules, with a moderate 550mg dose of organic astragalus powder per serving.

Key Benefits:

  • Supports immune function and kidney health
  • May help with DNA repair and aging defense
  • Easy once-a-day dosing (240 servings per bottle)
  • Budget-friendly with 8-month supply

Key Ingredients:

  • 550mg Organic Astragalus Powder (Astragalus membranaceus root) per capsule
  • Vegetarian capsule (Hypromellose), magnesium stearate, silica

Pros:

  • Organic, non-GMO, soy-free, gluten-free, and vegetarian-friendly
  • Manufactured in a GMP-compliant, FDA-registered facility
  • 240 capsules per bottle = long-lasting supply
  • Affordable price point

Cons:

  • Lower potency per capsule compared to standardized or extract-based formulas
  • No polysaccharide or active compound standardization

Customer Feedback:

  • Value for Money: Customers consistently highlight its excellent price-to-quality ratio. Many are impressed that one bottle can last up to 8 months, making it an economical daily wellness choice.
  • Immune Support: Users report noticeable benefits in immune resilience and some also suggest potential kidney and DNA repair support.
  • Quality: Feedback indicates that this is a reliable, well-made supplement, with several repeat buyers praising its consistency and value.

Best Suited For:

  • Budget-conscious users
  • Those seeking long-term immune support
  • Beginners wanting to try astragalus at an affordable cost

Usage Recommendations:
Take 1 capsule daily with food, or as recommended by your healthcare provider. Due to its mild dose, this product can be ideal for long-term, consistent use.

Summary: Nutricost Astragalus 550mg is a dependable, cost-effective choice for daily immune support. With 240 vegetarian capsules and organic sourcing, it’s a smart pick for users who value both simplicity and savings.

6. Best Liquid Astragalus Tincture: MaryRuth Organics Astragalus Root Drops (1 fl oz)

4.5 out of 5 (155+) from Amazon
MaryRuth Organics Astragalus Root Drops

Price: $14.95

MaryRuth Organics offers a USDA Organic Astragalus Root extract in liquid drop form, ideal for those who prefer tinctures over pills. It’s vegan, sugar-free, and free of alcohol, gluten, soy, and other allergens. The product is especially suitable for individuals looking for a quick-absorbing, natural immune booster with a clean ingredient profile.

Key Benefits

  • Supports immune system health and respiratory function
  • Promotes mental focus and energy balance
  • Easy-to-absorb liquid form for faster effects
  • Alcohol-free and gentle on the liver
  • Pleasant taste that blends well with water, coffee, or juice

Key Ingredients

  • Organic Astragalus Root Extract (1,180 mg per 1 mL serving)
  • Organic Glycerin
  • Purified Water
    Each 30 mL bottle offers about 30 servings.

Pros

  • USDA Organic, Vegan, Non-GMO, Gluten-Free, Sugar-Free
  • Alcohol-free and easy on digestion and liver
  • Tastes great according to reviews
  • Good for sensitive users or those avoiding capsules

Cons

  • Small bottle (only 30 servings)
  • Requires daily dosing 1–3x/day
  • Price per serving is higher compared to capsules

Customer Feedback:

  • Immune Support: Customers consistently reported improved immunity, fewer colds, and better energy during cold and flu season.
  • Taste: Users praised the flavor—many said it tasted pleasant and worked well mixed in water or juice.
  • Quality: Multiple reviews highlight the excellent quality of MaryRuth’s brand, with users noting consistency and satisfaction.
  • Ease of Use: Appreciated for its dropper format—simple to use, especially for those who dislike capsules or have trouble swallowing pills.

Best Suited For

  • Individuals seeking immune support in a liquid format
  • Those sensitive to alcohol-based tinctures
  • People on strict diets (gluten-free, vegan, etc.)
  • Users who prefer herbal tonics over pills

Usage Recommendations

Shake well before use. Take up to 30 drops (1 mL) 1 to 3 times per day directly or mixed in liquid. Best taken regularly for consistent immune support.

Summary: MaryRuth’s Astragalus liquid extract is a clean, potent immune-boosting formula with excellent taste and no alcohol. Ideal for those preferring herbal drops over capsules, it stands out for quality, purity, and ease of use.

Benefits of Astragalus Supplements

Astragalus supplements offer a wide range of science-backed and traditionally valued benefits, including:

  • Immune Support: Astragalus is rich in polysaccharides and saponins that help stimulate white blood cells and strengthen immune defenses.
  • Anti-Aging Effects: Some studies suggest astragaloside IV, a key compound in Astragalus, may support telomere integrity and slow cellular aging.
  • Energy & Vitality: Used as an adaptogen, Astragalus may help reduce fatigue and improve resilience to physical and mental stress.
  • Cardiovascular Support: May help improve circulation, support blood vessel integrity, and reduce oxidative stress on the heart.
  • Anti-Inflammatory Properties: Contains antioxidants that help reduce chronic inflammation, which is often linked to aging and disease.

How We Selected the Best Astragalus Supplements

Choosing a high-quality Astragalus supplement isn’t just about price or brand name. We evaluated dozens of products using the following criteria:

  • Form & Potency: Products featuring high-potency extracts (often standardized to astragaloside IV or 10:1 extract) were prioritized.
  • Ingredient Quality: Organic, non-GMO, and third-party tested ingredients are key for purity and safety.
  • Transparency: We favored brands that disclose full ingredient lists, dosage per serving, and manufacturing practices (GMP certified).
  • Customer Feedback: Only products with consistently high reviews from real users were considered.
  • Overall Value: We assessed cost per serving and formulation quality to ensure real value for your dollar.

Key Ingredients in Astragalus Supplements

While most supplements focus on Astragalus membranaceus root extract, there are a few variations worth noting:

  • Astragalus Root Powder: Offers the full spectrum of compounds but is typically lower in potency.
  • Standardized Extracts: Concentrated to contain specific amounts of astragaloside IV or polysaccharides—ideal for consistent results.
  • Synergistic Blends: Some formulas combine Astragalus with other herbs like ginseng or reishi to enhance adaptogenic and immune effects.

Common doses range from 500 mg to 1500 mg per serving, depending on the concentration and extract ratio (e.g., 10:1 extract).

Who Should Consider Taking Astragalus?

Astragalus may be beneficial for a wide range of people, especially:

  • Adults looking for daily immune support
  • People under chronic stress or fatigue
  • Those seeking natural anti-aging solutions
  • Individuals recovering from illness or low immunity
  • Athletes or active individuals looking to improve stamina and recovery

It’s a gentle adaptogen, meaning it can often be taken long-term with minimal risk of side effects.

How to Use Astragalus Supplements

For best results, follow these usage guidelines:

  • Typical Dose: 500 mg to 1500 mg per day, depending on extract strength.
  • Best Time to Take: Morning or early afternoon, ideally with food.
  • With or Without Food: Most capsules and powders are safe to take with meals for better absorption.
  • Cycle or Daily Use?: Astragalus can be used daily, but some users choose to cycle (e.g., 5 days on, 2 days off) for long-term adaptogen balance.

If you’re stacking it with other adaptogens like Ashwagandha or Rhodiola, consider spreading them throughout the day.

FAQ – Frequently Asked Questions

When is the best time to take Astragalus?

It’s best taken in the morning to support immune readiness and sustained energy throughout the day.

Is Astragalus safe for long-term use?

Yes. Astragalus is generally considered safe for extended use, especially in moderate doses. However, people on immune-modulating drugs should consult a doctor.

Can I combine Astragalus with other supplements?

Yes. It pairs well with adaptogens (e.g., ginseng, reishi), antioxidants (e.g., vitamin C), and daily wellness stacks.

How long until I see results?

Some users feel more energetic within 1–2 weeks, while deeper benefits like immune resilience or cellular support may take 4–6 weeks.

Are there any side effects?

Side effects are rare, but some individuals may experience mild gastrointestinal upset or allergic reactions. Stick to recommended doses to avoid issues.

Final Verdict

Astragalus is one of the most trusted herbs for natural immune support, stress resilience, and healthy aging. Whether you’re trying to stay well during cold season, boost your daily energy, or invest in long-term wellness, the right Astragalus supplement can make a real difference.

Sharing is caring!