Top 5 Best Dihydromyricetin (DHM) Supplements for Liver Support & Hangover Recovery

Dihydromyricetin (DHM), a natural flavonoid found in the Hovenia dulcis tree (also known as the Japanese raisin tree), has gained attention in recent years for its potential benefits in liver detoxification, alcohol recovery, and cognitive support. Whether you’re looking to reduce the effects of alcohol, protect your liver, or support your nervous system, DHM supplements can offer targeted support when used correctly.

In this guide, we explain the benefits of DHM, how to choose the right supplement, and everything else you need to know before buying.

Our Top Picks for Dihydromyricetin Supplements

1. Best Overall DHM Supplement: Double Wood DHM 300mg (50 Capsules)

• Why? Trusted brand with 300 mg DHM per capsule, third-party tested in the USA, non-GMO and gluten-free. Consistently praised for effectiveness in reducing hangover symptoms and supporting liver health.
• Key Benefits: Liver detox, antioxidant support, next-day recovery
• Best for: Users seeking a reliable, moderate-dose DHM from a reputable brand with clean testing standards

2. Best Value DHM Supplement: Nutricost DHM 350mg (90 Capsules)

• Why? Offers a high 350 mg DHM dose per capsule at a low cost per serving ($0.16). Vegan, non-GMO, gluten-free, and produced in a GMP facility—making it one of the best budget-friendly options
• Key Benefits: High-dose liver protection, supports alcohol metabolism, effective recovery
• Best for: Budget-conscious users who want high potency and a clean ingredient profile

3. Best High-Dose DHM Formula: Double Wood DHM1000 (30 Tablets)

• Why? Delivers 1,000 mg DHM per tablet with added electrolytes for hydration and liver recovery. Popular for its convenience and power in one pill
• Key Benefits: Intense liver support, electrolyte replenishment, improved sleep after drinking
• Best for: Those needing a strong, fast-acting dose for intense hangover relief and hydration

4. Best Multi-Ingredient Liver Formula: Nature’s Craft Nighttime Liver Detox (240 Capsules)

• Why? Combines DHM (1,000 mg), milk thistle, electrolytes, ginger, and B-vitamins for comprehensive support. Great for both pre- and post-drinking routines
• Key Benefits: Liver cleanse, hangover prevention, antioxidant and nutrient replenishment
• Best for: Users who want an all-in-one recovery solution with vitamins and herbal support

5. Best Clean DHM-Only Formula: DHM Depot Dihydromyricetin 300mg (90 Capsules)

• Why? Pure DHM sourced from Ampelopsis grossedentata, free from fillers and additives. Manufactured in the USA and third-party tested for quality
• Key Benefits: Supports liver detox, reduces alcohol effects, helps with next-day recovery
• Best for: Minimalists who want a straightforward, pure DHM supplement with no extras

Rank	Product	Form	Price per Count	Highlight	Key Benefits	Best For
1️⃣	Double Wood DHM 300mg (50ct)	Capsule	$0.36	Best Overall DHM Supplement	Liver detox, antioxidant support, next-day recovery	Users seeking a reliable, moderate-dose DHM from a reputable brand with clean testing standards
2️⃣	Nutricost DHM 350mg (90ct)	Capsule	$0.16	Best Value DHM Supplement	High-dose liver protection, supports alcohol metabolism, effective recovery	Budget-conscious users who want high potency and a clean ingredient profile
3️⃣	Double Wood DHM1000 (30ct)	Tablet	$0.73	Best High-Dose DHM Formula	Intense liver support, electrolyte replenishment, improved sleep after drinking	Those needing a strong, fast-acting dose for intense hangover relief and hydration
4️⃣	Nature’s Craft Nighttime Liver Detox (240ct)	Capsule	$0.15	Best Multi-Ingredient Liver Formula	Liver cleanse, hangover prevention, antioxidant and nutrient replenishment	Users who want an all-in-one recovery solution with vitamins and herbal support
5️⃣	DHM Depot Dihydromyricetin 300mg (90ct)	Capsule	$0.23	Best Clean DHM-Only Formula	Supports liver detox, reduces alcohol effects, helps with next-day recovery	Minimalists who want a straightforward, pure DHM supplement with no extras

1. Best Overall DHM Supplement: Double Wood DHM 300mg (50 Capsules)

Price: $19.95

DHM Depot by Double Wood Supplements offers a high-strength dose of 300mg of Dihydromyricetin per capsule, designed specifically to support liver detoxification and reduce the aftereffects of alcohol. With 50 capsules per bottle, this product is gluten-free, non-GMO, third-party tested, and manufactured in a GMP-certified facility in the USA.

Key Benefits

• Helps reduce hangover symptoms such as headaches, fatigue, and grogginess
• Supports liver detoxification and alcohol metabolism
• Promotes mental clarity and alertness after drinking
• May enhance sleep quality post-alcohol use
• Useful for maintaining wakefulness and energy the following day

Key Ingredients

• Dihydromyricetin (Ampelopsis grossedentata) – 300 mg per capsule
• Capsule made of gelatin

Pros

• High-potency formula (300mg per capsule)
• Third-party tested for purity and safety
• Manufactured in the USA in a GMP-certified facility
• Highly rated for alcohol recovery and clarity
• Non-GMO and gluten-free

Cons

• Capsule form only (not suitable for vegans due to gelatin)
• Dosage may need adjustment depending on alcohol intake

Customer Feedback:

• Effectiveness: Many users describe it as a game changer for alcohol recovery, noting noticeable effects within 30 minutes. They reported “no grogginess,” “no foggy feeling,” and “ready to party again.”
• Hangover Prevention: Highly praised for preventing next-day fatigue, with several users claiming it “eliminated hangovers completely” and made them feel normal the next day.
• Alcohol Effects: Users said it reduced intoxication and helped them feel more in control and less affected by drinking.
• Headache Relief: Reported to relieve alcohol-related headaches, dizziness, and brain fog.
• Value for Money: At ~$0.36 per capsule, it’s considered an affordable and no-nonsense solution that delivers.
• Wakefulness: Customers note better sleep and more energy upon waking. Some said they “woke up feeling clear-minded and refreshed.”
• Drinkability: Easy to incorporate into drinking routines; some users take it throughout the night.
• Clarity: Several report reduced brain fog and better cognitive performance the next morning.

Best Suited For

• Individuals who regularly consume alcohol and want reliable hangover support
• Those looking for liver detox and recovery aid
• People seeking cognitive clarity and better sleep after social drinking

Usage Recommendations
Take 1 capsule per 3 alcoholic drinks, ideally before bed with water. Users report better results when slightly increasing the dose depending on body weight or drinking intensity. For general detox, it can be used occasionally as needed.

Summary: DHM Depot’s 300mg Dihydromyricetin capsules are among the most effective hangover recovery tools on the market. Backed by strong customer reviews and third-party testing, this supplement is ideal for alcohol recovery, liver support, and next-day clarity—all at a reasonable price point.

2. Best Value DHM Supplement: Nutricost DHM 350mg (90 Capsules)

Price: $15.95

Nutricost’s Dihydromyricetin offers a potent 350mg of DHM per capsule, sourced from vine tea extract (Ampelopsis grossedentata). With 90 vegan-friendly capsules per bottle, it delivers a generous 3-month supply. This supplement is gluten-free, non-GMO, and manufactured in a GMP-compliant facility with third-party testing to ensure safety and potency.

Key Benefits

• Supports liver health and alcohol detoxification
• May help reduce hangover intensity and duration
• Suitable for vegans and those with gluten sensitivities
• High-dose formula for stronger protection
• Long-lasting supply with excellent cost-per-serving

Key Ingredients

• Dihydromyricetin (from vine tea extract) – 350 mg per capsule
• Other ingredients: Hypromellose (vegan capsule), magnesium stearate (vegetable source), silica

Pros

• Higher potency (350mg per capsule)
• Excellent value at only ~$0.16 per capsule
• Vegan, non-GMO, gluten-free
• Third-party tested and GMP-compliant
• 90-day supply per bottle

Cons

• A few users mention mild or subtle effects
• May require adjusted dosing based on alcohol intake or body weight

Customer Feedback:

• Effectiveness: Most users find the product effective for minimizing alcohol-related fatigue, with one stating it “stopped soreness” after late-night drinking. Others found one capsule sufficient for relief.
• Hangover Prevention: Widely praised for its ability to prevent next-day grogginess and hangovers. Multiple reviews describe waking up “refreshed” and without nausea or headache.
• Value for Money: Many customers consider it a “miracle pill” with “amazing value” thanks to the high dose and large count per bottle.
• Ease of Use: Users like the simplicity—just one capsule before or after drinking, or as needed. Some prefer taking multiple capsules for heavier drinking.
• Consistency: A few reviewers note it may take experimenting with timing and dosage to find the best result. Some light drinkers found even one capsule effective.

Best Suited For

• Those who drink socially and want a reliable daily-use option
• Budget-conscious users looking for a long-term liver and hangover support
• People following vegan or gluten-free diets

Usage Recommendations
Take 1 capsule before or after drinking. For heavier consumption, up to 2 capsules before and 2–4 after may be helpful. Best taken with water and possibly combined with hydration or electrolytes for optimal hangover prevention.

Summary: With a high 350mg DHM dose, vegan-friendly formula, and unbeatable price per serving, Nutricost’s Dihydromyricetin is a top choice for everyday users. It offers solid liver support, hangover prevention, and long-term value for those who drink occasionally or regularly.

3. Best High-Dose DHM Formula: Double Wood DHM1000 (30 Tablets)

Price: $38.98

DHM1000 by Double Wood Supplements delivers a powerful 1,000mg of Dihydromyricetin per tablet, paired with essential electrolytes for added hydration and recovery support. Each bottle contains 30 tablets (15 servings), designed to be taken post-alcohol consumption to enhance detox and reduce next-day symptoms. It’s third-party tested, gluten-free, non-GMO, and made in a GMP-certified facility in the USA.

Key Benefits

• Delivers ultra-high 2,000mg of DHM per serving (2 tablets)
• Helps prevent and reduce hangovers, nausea, and headaches
• Includes electrolytes (calcium, magnesium, potassium, sodium) to support hydration
• Improves sleep quality after alcohol use
• Supports liver detox and recovery

Key Ingredients

• Dihydromyricetin (DHM) – 1,000 mg per tablet (2,000 mg per serving)
• Electrolytes: Calcium (44 mg), Magnesium (22 mg), Chloride (354 mg), Sodium (200 mg), Potassium (62 mg)
• Other ingredients: Microcrystalline cellulose, magnesium stearate, silicon dioxide

Pros

• One of the highest DHM doses on the market
• Includes electrolytes for added hydration benefits
• Well-rated for effectiveness, quality, and sleep support
• Manufactured and tested in the USA
• Third-party verified for purity and potency

Cons

• Tablets are large and may be difficult to swallow for some
• Higher price per serving (~$0.73) compared to other options
• Limited servings per bottle (15 full servings)

Customer Feedback:

• Effectiveness: Widely praised for its strong impact on reducing hangover symptoms, especially when taken before bed. Many users say it’s the “most effective supplement” they’ve tried.
• Hangover Prevention: Customers consistently report less brain fog, fewer headaches, and reduced rebound anxiety the next morning.
• Sleep Quality: Many users say they wake up “rested” and “clear-headed,” even after nights of heavy drinking.
• Electrolyte Benefit: The inclusion of minerals is appreciated, especially for rehydration post-drinking.
• Value for Money: Considered worth the cost due to high DHM dosage and dual benefit (hangover + hydration).
• Tablet Size: A common downside is the large pill size, with some users finding them hard to swallow.

Best Suited For

• Heavy drinkers or those needing fast, strong hangover recovery
• Individuals wanting added hydration and sleep support
• Users who prefer a high-dose supplement in fewer tablets

Usage Recommendations
Take 2 tablets per 2–3 alcoholic drinks, ideally before bed with water. Do not exceed 8 tablets per day. For best results, combine with hydration and avoid exceeding your alcohol tolerance.

Summary: DHM1000 by Double Wood is the strongest DHM supplement available, combining 2,000mg of DHM per serving with electrolytes for superior liver and hydration support. It’s ideal for serious hangover prevention but comes with the tradeoff of large pill size and a higher cost per dose.

4. Best Multi-Ingredient Liver Formula: Nature’s Craft Nighttime Liver Detox (240 Capsules)

Price: $44.99

Nature’s Craft Hang-12 is a post-drinking support supplement formulated with a combination of DHM (dihydromyricetin), milk thistle, electrolytes, and liver-supportive vitamins. Each bottle contains 240 capsules—enough for up to 80 servings—making it ideal for regular use during social drinking periods.

Key Benefits

• Helps reduce hangover symptoms like headache, fatigue, and nausea
• Supports nighttime liver detox and hydration
• Provides antioxidant and electrolyte support
• Promotes better sleep and next-day energy

Key Ingredients (per 3-capsule serving)

• DHM (from Ampelopsis grossedentata) – 1,000 mg
• Milk Thistle, Ginger Root, Prickly Pear – 300 mg liver support blend
• Vitamin B12 (Cyanocobalamin) – 50 mcg (2083% DV)
• Vitamin B6, C, Thiamine, Calcium, Magnesium, Sodium, Potassium

Pros

• High-dose DHM plus herbal liver support
• Includes hydration electrolytes and energy-boosting B vitamins
• Made in a GMP-certified facility and lab tested in the USA
• Good value per capsule, especially with bulk size option

Cons

• Requires 6 capsules per use (3 before drinking, 3 before bed)
• Mixed reviews on effectiveness for heavy drinkers
• Some may find the number of pills inconvenient

Customer Feedback:

• Effectiveness: Users report better mornings, fewer hangover symptoms, and improved energy.
• Headache Relief: Many note reduced or no headaches the next day.
• Functionality: Works best when taken both before and after drinking.
• Value for Money: Considered affordable compared to other multi-ingredient formulas.
• Liver Health: Praised for aiding liver detox and protecting against alcohol effects.

Best Suited For
Adults who drink socially or moderately and want a comprehensive, pre- and post-drinking recovery formula that supports liver function, hydration, and morning-after clarity.

Usage Recommendations
Take 3 capsules before drinking and 3 more before bed, preferably with a full glass of water. Consistency enhances results.

Summary: Nature’s Craft Hang-12 stands out as a complete post-drinking support supplement with DHM, milk thistle, electrolytes, and vitamins for hangover recovery and liver care. It’s ideal for those seeking a natural, well-rounded solution for better mornings after drinking.

5. Best Clean DHM-Only Formula: DHM Depot Dihydromyricetin 300mg (90 Capsules)

Price: $22.95

DHM Depot offers a straightforward liver support supplement with 300mg of pure dihydromyricetin (DHM) per capsule. Sourced from Ampelopsis grossedentata, this product is designed for adults seeking help with alcohol metabolism and post-drinking recovery. It comes in a bottle of 90 capsules and is third-party tested in the USA.

Key Benefits

• Supports liver detoxification after alcohol intake
• Helps reduce hangover symptoms such as nausea, headache, and fatigue
• Promotes faster breakdown of alcohol in the body
• May reduce alcohol cravings
• Enables better next-day functionality after drinking

Key Ingredients

• Dihydromyricetin (DHM) – 300mg per capsule
• Other ingredients: Gelatin (capsule)

Pros

• Made in the USA with globally sourced ingredients
• GMP-certified and third-party tested
• No fillers or proprietary blends – only DHM
• Easy-to-follow dosage (1 capsule per 3 drinks)
• Affordable at around $0.23 per capsule

Cons

• Some reports of capsules arriving broken or damaged
• Lower DHM dose per capsule compared to competitors (may require multiple capsules for heavy drinkers)

Customer Feedback:

• Alcohol Metabolism: Users say it helps speed up alcohol breakdown and reduces cravings. Some note improved tolerance to wine or spirits without next-day grogginess.
• Effectiveness: Many call it a “hangover lifesaver”, especially for heavy drinkers. Most feel functional and clear-headed the next day.
• Feel Good Factor: Users report feeling normal or energized, with no nausea or fog the next day.
• Value for Money: Customers find it reasonably priced, calling it “worth every penny” and “affordable magic.”
• Pill Quality: Feedback is mixed – some say the pills are great, others report damaged or broken capsules in shipment.

Best Suited For

• Adults looking for a pure DHM-only supplement
• People who want alcohol detox support without additional herbs or electrolytes
• Budget-conscious users preferring a low-cost, minimalist formula

Usage Recommendations
Take 1 capsule per 3 alcoholic drinks, ideally before bed with a glass of water. A larger dose may be used for better results if needed.

Summary: DHM Depot’s 300mg capsules are a solid choice for those wanting clean, affordable DHM support. It’s especially valued for its simplicity and effectiveness, though users may need to take more than one capsule after heavy drinking.

What Is Dihydromyricetin (DHM)?

Dihydromyricetin is a bioactive compound extracted primarily from the Hovenia dulcis plant, traditionally used in East Asia to reduce hangovers and support liver health. It belongs to the flavonoid family, known for its antioxidant and anti-inflammatory properties.

Modern research suggests that DHM may modulate GABA receptors in the brain—helping reduce alcohol’s effects—and promote liver detoxification enzymes that clear acetaldehyde, the toxic byproduct of alcohol metabolism.

Potential Benefits of Dihydromyricetin

DHM supplements offer a range of health benefits, especially for those who occasionally consume alcohol or want to support liver and neurological health:

• Supports Alcohol Metabolism: DHM helps accelerate the breakdown of acetaldehyde, potentially reducing hangover symptoms like headaches and nausea.
• Protects Liver Function: It may reduce liver inflammation and oxidative stress caused by alcohol or environmental toxins.
• Neuroprotection: Studies suggest DHM can help protect against alcohol-induced damage to the brain and nervous system.
• Improves Sleep After Drinking: DHM may counteract the sleep-disrupting effects of alcohol by modulating GABAergic activity.
• General Detox Support: Even for non-drinkers, DHM can support the body’s detox pathways and antioxidant defense.

How to Choose a Quality DHM Supplement

When choosing a DHM supplement, consider these factors:

• Source and Purity: Look for DHM extracted from Hovenia dulcis, not synthetic alternatives. Ideally, the product should be third-party tested for purity.
• Effective Dosage: Most studies use 100–300 mg per dose. A supplement that provides at least 100 mg of DHM per serving is a good baseline.
• Form: Available in capsules, powder, and chewables. Capsules are more common and convenient, while powders may be better for flexible dosing.
• Additional Ingredients: Some formulas include milk thistle, NAC, or electrolytes for enhanced liver or alcohol recovery support.
• Manufacturing Quality: Choose products made in cGMP-certified and FDA-registered facilities in the U.S. with transparent labeling and no hidden fillers.

FAQs about Dihydromyricetin Supplements

Final Verdict

Dihydromyricetin is more than just a hangover remedy. With growing research supporting its neuroprotective, liver-supportive, and detox-enhancing properties, DHM supplements are a smart choice for anyone looking to reduce alcohol’s impact or boost overall wellness.

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