Best 5 Pterostilbene Supplements for Brain, Heart & Longevity Support

Pterostilbene is gaining attention as a powerful antioxidant compound, often compared to resveratrol — but with better absorption and longer-lasting effects. Whether you’re aiming to support brain health, reduce oxidative stress, or promote healthy aging, a quality Pterostilbene supplement can be a valuable addition to your routine.

In this guide, we’ll cover the key benefits of Pterostilbene, how to choose the right supplement, and what to know before buying. But first, let’s look at our top picks.

Our Top Picks for Pterostilbene Supplements

1. Best Overall Pterostilbene: Double Wood Pterostilbene 100mg (60 Capsules)

• Why? Offers a clean, reliable formula with 100 mg of pterostilbene per capsule, manufactured in the USA and third-party tested. Backed by thousands of ratings, this supplement supports brain health, antioxidant defense, and aging support at a competitive price.
• Key Benefits: Antioxidant protection, cognitive support, healthy aging.
• Best for: Individuals seeking a trusted, research-backed daily antioxidant for long-term wellness.

2. Best Dual Antioxidant Combo: NatureBell Pterostilbene + 98% Resveratrol (200 Capsules)

• Why? Delivers 200 mg of trans-pterostilbene and 20 mg of ultra-pure resveratrol per serving. Combines two highly bioavailable antioxidants in a synergistic formula, with 100 servings per bottle.
• Key Benefits: Supports cardiovascular health, memory, immune function, and cellular protection.
• Best for: Users looking for a two-in-one antioxidant formula with high absorption and value.

3. Best Value for Daily Use: Nutricost Pterostilbene 100mg (120 Capsules)

• Why? Each capsule contains 100 mg of pterostilbene, with 120 servings per bottle at a very affordable price point. Non-GMO, gluten-free, and produced in a GMP-compliant facility.
• Key Benefits: Promotes nail and skin health, supports immune function, and overall cellular longevity.
• Best for: Budget-conscious users looking for a clean and consistent pterostilbene supplement for everyday wellness.

4. Best for Healthy Aging and Cognitive Clarity: Jarrow Formulas trans-Pterostilbene 50mg (60 Capsules)

• Why? Sourced from Silbinol (Pterocarpus marsupium), this vegan-friendly trans-pterostilbene formula is especially noted for enhancing mental clarity, energy, and inflammation response—while being gentle on the stomach.
• Key Benefits: Supports brain function, antioxidant defense, and healthy aging.
• Best for: Adults focused on cognitive support, energy balance, and graceful aging.

5. Best High-Potency Longevity Formula: ProHealth Pterostilbene Pro 250mg (60 Capsules)

• Why? Delivers 250 mg of trans-pterostilbene per capsule—5x higher than many standard formulas—with clinical backing. Promotes sirtuin activation, autophagy, and neuroprotection with superior purity.
• Key Benefits: Supports cardiovascular function, memory, energy, and mitochondrial rejuvenation.
• Best for: Advanced users, biohackers, or longevity enthusiasts seeking maximum cellular and metabolic support.

Rank	Product	Form	Price per Count	Highlight	Key Benefits	Best For
1️⃣	Double Wood Pterostilbene 100mg (60ct)	Capsule	$0.30	Best Overall Pterostilbene	Antioxidant support, brain health, healthy aging	Users seeking a trusted daily antioxidant
2️⃣	NatureBell Pterostilbene + Resveratrol 200mg (200ct)	Capsule	$0.20	Best Dual Antioxidant Combo	Cardiovascular support, memory, immune health	Those wanting trans-pterostilbene & resveratrol combo
3️⃣	Nutricost Pterostilbene 100mg (120ct)	Capsule	$0.16	Best Value for Daily Use	Nail & skin support, antioxidant defense	Budget-conscious users needing consistent support
4️⃣	Jarrow Formulas trans-Pterostilbene 50mg (60ct)	Veggie Capsule	$0.36	Best for Healthy Aging & Clarity	Brain function, inflammation, energy support	Adults focused on aging, cognition, inflammation
5️⃣	ProHealth Pterostilbene Pro 250mg (60ct)	Capsule	$0.42	Best High-Potency Longevity Formula	Sirtuin activation, memory, autophagy, heart health	Biohackers or those needing maximum support

1. Best Overall Pterostilbene: Double Wood Pterostilbene 100mg (60 Capsules)

Price: $19.95

Double Wood’s Pterostilbene is a well-known, high-quality supplement offering 100 mg of Pterostilbene per capsule. It’s made in the USA, third-party tested, and free from GMOs and gluten. This product is ideal for adults seeking daily antioxidant support, cognitive enhancement, and healthy aging benefits.

Key Benefits

• Supports cognitive clarity and brain cell health
• Helps maintain healthy cholesterol and blood sugar levels
• Promotes cellular antioxidant protection
• May support energy, longevity, and mood
• Convenient once-daily capsule

Key Ingredients

• Pterostilbene (100 mg per capsule)
• Capsule form: gelatin, with microcrystalline cellulose and vegetable stearate
• Suggested use: 1 capsule daily

Pros

• High-potency 100 mg per serving
• Manufactured in the USA with globally sourced ingredients
• Third-party tested for purity and potency
• Affordable price (~$0.30 per count)
• Positive reviews on effectiveness, clarity, energy, and value

Cons

• Contains gelatin (not suitable for vegans)
• No additional synergistic ingredients like resveratrol or NMN
• Independent lab testing not disclosed beyond third-party mention

Customer Feedback

• Effectiveness: Over 200 customers praise its clear impact on cognition, cholesterol, and antioxidant defense. One user noted improved cholesterol levels after 8 months of use.
• Mental Clarity: Many users report sharper thinking, better memory recall, and reduced “brain fog” — especially in older adults.
• Energy Level: Users often describe a noticeable increase in daily stamina and physical motivation.
• Antioxidant Power: Reviewers mention reduced inflammation, immune support, and possible blood sugar balance.
• Quality: American-made, well-encapsulated, and consistently reliable — users appreciate its production transparency.
• Value for Money: At under $18 for 60 capsules, it’s seen as more affordable and more effective than many resveratrol alternatives.
• Feel Good: Reports of better mood, improved skin and joint comfort, and no gastrointestinal side effects.
• Blood Sugar Control: Some users report improved insulin sensitivity and more stable glucose levels.

Best Suited For

Adults looking to support healthy aging, cognitive clarity, and antioxidant protection — especially those who want a standalone, affordable daily dose of Pterostilbene.

Usage Recommendations

Take 1 capsule per day, preferably with a meal to support absorption. Can be paired with resveratrol or NAD+ boosters for enhanced longevity support.

Summary: Double Wood’s Pterostilbene stands out for its high potency, third-party testing, and strong customer satisfaction across cognition, energy, and antioxidant effects — making it a top choice for those seeking a simple and effective longevity supplement.

2. Best Dual Antioxidant Combo: NatureBell Pterostilbene + 98% Resveratrol (200 Capsules)

Price: $24.95

NatureBell offers a 2-in-1 supplement combining 200 mg of Pterostilbene and 20 mg of 98% pure Trans-Resveratrol per serving. With 200 capsules per bottle and a reputation for clean, lab-tested ingredients, it delivers potent antioxidant and anti-aging support in a long-lasting supply. Ideal for those seeking a synergistic boost for cognitive, cardiovascular, and immune function.

Key Benefits

• Dual antioxidant support from Pterostilbene + Trans-Resveratrol
• May enhance memory, focus, and brain health
• Supports cardiovascular and cellular longevity
• Helps improve antioxidant status and immune response
• Non-GMO and free from common allergens

Key Ingredients

• Trans-Pterostilbene (Dimethylresveratrol): 200 mg
• Trans-Resveratrol (98% pure): 20 mg
• Serving size: 2 capsules
• Suggested use: 2 capsules daily
• Other ingredients: Silicon dioxide, rice flour, gelatin, magnesium stearate

Pros

• High-strength formula (200 mg Pterostilbene per serving)
• Synergistic pairing with resveratrol for enhanced efficacy
• Non-GMO, gluten-free, dairy-free, soy-free, and preservative-free
• Large bottle (100 servings) offers long-term value
• Third-party lab tested in the USA
• UV-protected amber bottle for freshness

Cons

• Gelatin capsules – not vegan-friendly
• Serving size is 2 capsules per dose
• Some users note lack of company response to inquiries

Customer Feedback

• Brain Health: Users report improved mental sharpness, energy, and cognitive clarity. One even called their memory “bizarrely better.”
• Quality: Multiple users praised the clean formula and long-lasting bottle. The product is frequently described as high quality and reliably effective.
• Value for Money: Customers find it a great deal, especially considering the dual-ingredient formula and large capsule count.
• Antioxidant Power: Many reviews highlight stronger cardiovascular support and immune protection compared to resveratrol alone.
• Effectiveness: Noted for improving focus, stamina, and even pain relief in some users.
• Feel Good: Users say it’s easy to swallow, has no side effects, and makes them feel healthier overall.
• Memory Support: Reports include better recall and stronger long-term memory.
• Pain Relief: Some experienced relief from chronic issues like leg cramps or inflammation.

Best Suited For

Individuals seeking an advanced anti-aging formula that combines Pterostilbene and Resveratrol for maximum antioxidant protection, memory support, and cardiovascular benefits.

Usage Recommendations

Take 2 capsules daily, preferably with food. Best taken consistently over time for optimal results in aging, energy, and cognitive health.

Summary: NatureBell Pterostilbene with Resveratrol delivers a high-potency, synergistic antioxidant combo ideal for long-term brain, heart, and immune support. With clean sourcing and great value per serving, it’s a top choice for comprehensive healthy aging.

3. Best Value for Daily Use: Nutricost Pterostilbene 100mg (120 Capsules)

Price: $19.95

Nutricost offers a straightforward, high-quality pterostilbene supplement with 100 mg per capsule and 120 servings per bottle. It’s a simple, no-frills option made in a GMP-compliant facility and tested for purity. Perfect for users seeking an affordable, clean formula without unnecessary ingredients.

Key Benefits

• Supports antioxidant activity and healthy aging
• May improve cognitive clarity and cellular function
• Clean label: No fillers, soy, or gluten
• Excellent value for long-term daily use
• GMP-certified production for quality assurance

Key Ingredients

• Pterostilbene: 100 mg per capsule
• Serving size: 1 capsule
• Other ingredients: Rice flour, gelatin capsule
• 120 capsules per bottle (120 servings)

Pros

• One of the most affordable per-capsule prices
• Simple, single-ingredient formula
• Non-GMO and gluten-free
• Produced in a GMP-compliant facility
• No artificial additives or preservatives
• 120-day supply in one bottle

Cons

• No added synergistic compounds like resveratrol
• Gelatin-based capsule not suitable for vegans
• Lacks third-party testing details on the product page

Customer Feedback

• Effectiveness:
  Users noted benefits like improved energy and stronger nails. Some reviewers even reported visible physical improvements within a month (e.g., healthier nail strength).
• Quality:
  Customers generally describe the supplement as high quality and trustworthy, mentioning its consistent formulation.
• Value for Money:
  Widely praised as an excellent value due to the low cost per capsule and high quantity. Multiple reviewers chose this brand because of its affordability.
• Satisfaction:
  While some users weren’t sure about noticeable effects, the majority experienced positive health changes. Many use it as part of a broader wellness or anti-aging regimen.

Best Suited For

Ideal for budget-conscious users who want a pure, effective daily pterostilbene supplement without any extras. Great for long-term antioxidant and anti-aging support.

Usage Recommendations

Take 1 capsule per day, preferably with food. Can be stacked with other supplements like resveratrol or NAD+ boosters for enhanced benefits.

Summary: Nutricost Pterostilbene 100mg offers a clean, affordable solution for those who want a simple and effective way to support longevity and cellular health. With 120 capsules at a budget-friendly price, it’s hard to beat for value.

4. Best for Healthy Aging and Cognitive Clarity: Jarrow Formulas trans-Pterostilbene 50mg (60 Capsules)

Price: $23.45

Jarrow Formulas offers a vegan-friendly pterostilbene supplement delivering 50 mg per capsule from Silbinol®, a natural source derived from the Indian Kino tree. It’s designed to support healthy aging, brain and cardiovascular function, and antioxidant protection, with a clean-label formula free from major allergens.

Key Benefits

• Supports healthy aging by activating sirtuins
• Promotes mitochondrial and cellular function
• Enhances antioxidant defense and cardiovascular health
• May improve cognitive clarity and sleep quality
• Gentle and suitable for sensitive users

Key Ingredients

• trans-Pterostilbene – 50 mg per capsule
  (from 56 mg of Pterocarpus marsupium wood extract – Silbinol®)
• Other ingredients: Microcrystalline cellulose, HPMC (capsule), silicon dioxide, magnesium stearate (vegetable source)

Pros

• Derived from a natural botanical source
• Vegan, gluten-free, non-GMO
• No artificial additives or major allergens
• Positive user feedback on energy, sleep, mental clarity, and pain relief
• Reliable brand with consistent quality

Cons

• Lower dose (50 mg) compared to other products
• Slightly higher cost per serving (~$0.36)
• Not combined with resveratrol or other synergistic compounds

Customer Feedback

• Value for Money:
  Users feel it’s reasonably priced, especially compared to similar competitors like Elysium. Many appreciate the balance of price and performance. “Fairly priced and easy to take.”
  “The price is right!”
• Health Benefits:
  Customers highlight antioxidant, anti-inflammatory, and cholesterol-lowering effects, plus no gut issues. “Strong antioxidant capabilities… lowering blood pressure.”
  “No side effects on my gut… highly recommend.”
• Effectiveness:
  Works quickly for some, with noticeable benefits in mood, focus, and cognition. “Started working within three hours.”
  “Very effective and cost effective.”
• Energy Level:
  Multiple users noticed more energy and stamina during the day. “More energy and buoyant energetically.”
  “A dramatic improvement… energy and mental acuity.”
• Mental Clarity:
  Reported improvements in cognition, verbal fluency, and focus. “Able to think more clearly and speak more lucidly.”
  “More focused mentally.”
• Pain Level:
  Some users felt reduced joint pain, knee discomfort, and anxiety. “Knees no longer ached.”
  “Helpful for mild to moderate anxiety.”
• Sleep Quality:
  Several customers noticed better sleep and more restful mornings. “Sleeping better than I’ve slept in months.”
  “Feel much better and less stressed.”

Best Suited For

• Vegans and those avoiding allergens
• Individuals starting with a low pterostilbene dose
• Older adults seeking gentle mitochondrial and brain support
• Anyone sensitive to higher-potency formulas or seeking steady daily energy

Usage Recommendations

• Take 1 veggie capsule per day, preferably with a meal
• Consistency over several weeks yields the best results
• Can be stacked with NAD+ or resveratrol for enhanced effects

Summary: Jarrow Formulas Pterostilbene is a clean, gentle, plant-based option ideal for daily antioxidant and brain support. It’s a great fit for sensitive users and those seeking reliable energy, mental clarity, and sleep enhancement without any major allergens.

5. Best High-Potency Longevity Formula: ProHealth Pterostilbene Pro 250mg (60 Capsules)

Price: $29.15

ProHealth’s Pterostilbene Pro 250 is a high-strength antioxidant supplement designed for adults seeking anti-aging support, heart health, and cognitive function enhancement. Each capsule delivers 250 mg of trans-pterostilbene and is vegan, gluten-free, and free from common allergens.

Key Benefits

• Supports brain function by crossing the blood-brain barrier
• Promotes cardiovascular health by improving endothelial function
• Activates sirtuins and autophagy pathways for cellular renewal
• Provides potent antioxidant protection against oxidative stress
• May help improve stamina and energy levels

Key Ingredients

• Trans-Pterostilbene – 250 mg per capsule
  • Derived from natural sources
  • Delivered in a vegetable capsule with organic rice flour

Pros

• High potency (250 mg per capsule)
• Free from gluten, dairy, soy, and artificial additives
• Suitable for vegan and vegetarian diets
• Third-party tested for purity and safety
• Clinically supported for bioavailability and sirtuin activation

Cons

• Higher price per count ($0.42) compared to lower-dose alternatives
• May be excessive for beginners or those seeking lower dosages

Customer Feedback:

• Ease of Swallow: Capsules are described as easy to swallow with no complaints of size or taste.
• Health Benefits: Users report increased stamina, better gym performance, and anti-aging support at the cellular level.
• Effectiveness: Several customers noted improved energy and a reduction in body fat over time.
• Ease of Use: Many find it simple to add to their daily routine and mention it pairs well with NMN or other longevity stacks.

Best Suited For

• Biohackers and longevity enthusiasts
• Adults over 35 aiming to slow aging and boost cognitive/vascular health
• Those looking for a higher-potency alternative to resveratrol

Usage Recommendations
Take 1 capsule daily (preferably in the morning with food), or up to 2 capsules per day under the supervision of a healthcare provider.

Summary: ProHealth Pterostilbene Pro 250 stands out with its clinically-backed, high-dose trans-pterostilbene formula. Ideal for users prioritizing longevity, anti-aging, and brain support in a vegan-friendly, allergen-free format.

Why Trust This Guide?

We analyzed dozens of Pterostilbene supplements based on ingredient quality, dosage, formulation, price per serving, and verified customer feedback. This article is designed for U.S. readers looking for honest, science-based information with real-world buying guidance.

Benefits of Pterostilbene

Pterostilbene is a naturally occurring stilbenoid found in blueberries, grapes, and certain types of bark. It is structurally similar to resveratrol, but with better bioavailability, meaning your body can absorb and use it more effectively.

Here are some key benefits backed by early research:

• Brain & Cognitive Support: May help improve memory, focus, and protect against age-related cognitive decline.
• Cellular Protection: Acts as a potent antioxidant that helps fight free radical damage at the cellular level.
• Longevity & Anti-Aging: Activates SIRT1 (similar to resveratrol), potentially supporting healthier aging and mitochondrial function.
• Cardiovascular Health: May help reduce oxidative stress and support blood vessel function.
• Anti-Inflammatory Effects: Can help modulate inflammatory markers in the body.

How to Choose the Right Pterostilbene Supplement

When choosing a Pterostilbene supplement, here are some key factors to consider:

• Dosage per Serving: Effective doses typically range from 50 mg to 150 mg per day.
• Standalone vs Combo Formulas: Some supplements combine Pterostilbene with resveratrol, NMN, or cofactors to enhance results.
• Form & Purity: Look for vegan capsules, non-GMO, and third-party tested options.
• Bioavailability: Pterostilbene is generally well-absorbed, but lipid-based formulations or capsules with absorption aids may further improve uptake.
• Price per Count: Compare cost per serving, not just the bottle price.

FAQs About Pterostilbene Supplements

Final Verdict

Pterostilbene stands out as a highly bioavailable antioxidant that can support brain health, cellular protection, and healthy aging. Whether you’re interested in longevity, cognitive function, or simply enhancing your overall wellness routine, choosing the right Pterostilbene supplement can make a big difference.

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