- Our Top Picks for TUDCA Supplements
- 1. Best Overall TUDCA Supplement: Nutricost TUDCA 250mg (60 Capsules)
- 2. Best Dual-Function Bile Salt Formula: Double Wood TUDCA 250mg (60 Capsules)
- 3. Best Clinically Dosed & Vegan-Friendly TUDCA: Force Factor TUDCA 250mg (60 Vegetable Capsules)
- 4. Best TUDCA for Full Body Detox: Nature’s Craft TUDCA 500mg (60 Capsules)
- 5. Best High-Dose + Herbal Combo: Vinatura TUDCA with Milk Thistle 1250mg (90 Capsules)
- 6. Best TUDCA + Ox Bile Support: NatureBell TUDCA 500mg with Ox Bile 125mg (120 Capsules)
- 7. Best Entry-Level High-Potency TUDCA: Primaforce TUDCA 500mg (30 Capsules)
- What Is TUDCA?
- Benefits of TUDCA Supplements
- How We Chose the Best TUDCA Supplements
- Potential Side Effects of TUDCA
- Who Should Consider Taking TUDCA?
- How to Take TUDCA Supplements
- FAQ – Frequently Asked Questions
- Final Verdict
TUDCA, short for tauroursodeoxycholic acid, has become one of the most trusted supplements for liver support, bile flow, and metabolic health. Whether you’re dealing with fatty liver, sluggish digestion, or simply looking to optimize detox pathways, TUDCA is gaining momentum in the U.S. as a biohacker-approved compound.
In this guide, we break down what TUDCA is, how it benefits your health, and how to choose the best TUDCA supplement for your goals.
Our Top Picks for TUDCA Supplements
We’ve researched dozens of options and narrowed it down to the top 7 best TUDCA supplements based on purity, potency, brand transparency, and real customer feedback.
1. Best Overall TUDCA Supplement: Nutricost TUDCA 250mg (60 Capsules)
- Why? Trusted by thousands with over 7,000 monthly purchases, Nutricost delivers 250 mg of high-quality TUDCA per capsule. It’s 3rd-party tested, non-GMO, gluten-free, and made in a GMP facility in the USA.
- Key Benefits: Supports liver enzyme levels, bile flow, and metabolic detoxification.
- Best for: General users looking for a clean, reliable, and affordable TUDCA supplement.
2. Best Dual-Function Bile Salt Formula: Double Wood TUDCA 250mg (60 Capsules)
- Why? Delivers pure bile salt TUDCA with clinical support for liver, gallbladder, immune, and thyroid health. Highly rated and rigorously tested in the USA, ideal for long-term liver and digestion support.
- Key Benefits: Promotes gallbladder function, healthy liver enzymes, and detox pathways.
- Best for: Those seeking a multi-system bile acid supplement backed by research.
3. Best Clinically Dosed & Vegan-Friendly TUDCA: Force Factor TUDCA 250mg (60 Vegetable Capsules)
- Why? Uses a clinically backed 250 mg dose of pure TUDCA with added digestive benefits. It’s vegan, clean-label, and made in a GMP-certified U.S. facility.
- Key Benefits: Aids bile flow, reduces acid reflux, supports gut-liver axis.
- Best for: Vegans and wellness-focused individuals wanting a clinical dose in clean form.
4. Best TUDCA for Full Body Detox: Nature’s Craft TUDCA 500mg (60 Capsules)
- Why? A higher-strength bile salt supplement promoting liver, gallbladder, kidney, and digestive wellness. Combines detoxification with brain and energy support in one formula.
- Key Benefits: Enhances liver enzymes, bile production, and systemic detox.
- Best for: Users looking for broad-spectrum detox including memory and kidney support.
5. Best High-Dose + Herbal Combo: Vinatura TUDCA with Milk Thistle 1250mg (90 Capsules)
- Why? Delivers a potent 1000 mg TUDCA and 250 mg standardized milk thistle per serving—one of the highest concentrations available. 3rd-party tested and USA made.
- Key Benefits: Powerful liver detox, antioxidant support, and bile salt synergy.
- Best for: Experienced users needing aggressive liver and bile flow support.
6. Best TUDCA + Ox Bile Support: NatureBell TUDCA 500mg with Ox Bile 125mg (120 Capsules)
- Why? Combines Livamate TUDCA with 125 mg Ox Bile in a 3-capsule dose, enhancing digestion and nutrient absorption. Non-GMO, allergen-free, and third-party tested.
- Key Benefits: Improves bile flow, digestion, and supports gut-liver health.
- Best for: Those without gallbladders or needing extra bile acid for fat digestion.
7. Best Entry-Level High-Potency TUDCA: Primaforce TUDCA 500mg (30 Capsules)
- Why? Delivers 500 mg of pure TUDCA per capsule in a clean, NSF-certified formula. Ideal for short-term use or first-time high-dose trials.
- Key Benefits: Convenient daily dosing, supports consistent liver health.
- Best for: New users seeking a potent dose in a small, reliable supply.
Rank | Product | Form | Price per Count | Highlight | Key Benefits | Best For |
---|---|---|---|---|---|---|
1️⃣ | Nutricost TUDCA 250mg (60ct) | Capsule | $0.37 | Best Overall TUDCA Supplement | Liver enzyme support, bile flow, metabolic detox | Users wanting clean, affordable, reliable TUDCA |
2️⃣ | Double Wood TUDCA 250mg (60ct) | Capsule | $0.42 | Best Dual-Function Bile Salt Formula | Gallbladder support, immune & thyroid health | Those needing multi-organ support with bile salts |
3️⃣ | Force Factor TUDCA 250mg (60ct) | Capsule | $0.42 | Best Clinically Dosed & Vegan-Friendly TUDCA | Bile flow, acid reflux relief, gut-liver support | Vegans seeking a clinical dose with clean label |
4️⃣ | Nature’s Craft TUDCA 500mg (60ct) | Capsule | $0.43 | Best TUDCA for Full Body Detox | Liver enzyme boost, detox, memory support | Users looking for full-body detox support |
5️⃣ | Vinatura TUDCA + Milk Thistle 1250mg (90ct) | Capsule | $0.28 | Best High-Dose + Herbal Combo | Liver antioxidant support, bile salt synergy | Experienced users needing aggressive liver support |
6️⃣ | NatureBell TUDCA 500mg + Ox Bile 125mg (120ct) | Capsule | $0.28 | Best TUDCA + Ox Bile Support | Digestion, bile flow, nutrient absorption | Individuals without gallbladders or low bile |
7️⃣ | Primaforce TUDCA 500mg (30ct) | Capsule | $0.74 | Best Entry-Level High-Potency TUDCA | Potent daily dose, convenient 30-day supply | First-time users testing higher-potency dosing |
1. Best Overall TUDCA Supplement: Nutricost TUDCA 250mg (60 Capsules)
Price: $24.94
Nutricost’s TUDCA 250mg offers a clean, clinically dosed formula designed to support liver health, bile flow, and cellular detox. Manufactured in an FDA-registered, GMP-compliant facility, it has earned the trust of thousands of U.S. users and remains a consistent bestseller on Amazon.
Key Benefits
- Promotes healthy liver enzyme levels and liver detox
- Supports bile flow and gallbladder function
- Enhances mitochondrial and cellular protection
- Aids digestion and gut health
- Non-GMO, gluten-free, soy-free
Key Ingredients
- TUDCA (Tauroursodeoxycholic Acid): 250 mg per capsule
- Form: Gelatin capsule
- Serving Size: 1 capsule per day
- Other ingredients: Rice flour, gelatin, magnesium stearate (veg source), di-calcium phosphate, silica
Pros
- High-quality TUDCA at an effective daily dose
- Third-party tested for purity and potency
- Made in a GMP-compliant, FDA-registered facility
- Affordable and widely available
- No fillers or unnecessary ingredients
Cons
- Capsule contains gelatin (not vegan-friendly)
- Some users report mild GI upset or bitter aftertaste
Customer Feedback
- Liver Function: Most users report significant improvements in liver enzyme values and symptoms of fatty liver. Some mention benefits for gallbladder issues.
- Effectiveness: Many customers say they noticed results in less than 2 weeks, especially in energy, digestion, and reduced bloating.
- Ease of Use: Capsules are small and easy to swallow. No need to split dosing.
- Side Effects: Mixed feedback — most tolerate it well, but a few report nausea or digestive discomfort.
- Value for Money: The product is generally viewed as affordable given the quality and dosage, though a few feel it’s slightly pricey.
Best Suited For
Adults looking to improve liver function, especially those with fatty liver, gallbladder issues, or detox goals. Also ideal for biohackers or those stacking liver support nutrients.
Usage Recommendations
Take 1 capsule daily with food. For enhanced liver support, some users combine this with NAC or milk thistle. Drink plenty of water and monitor how your body responds.
Summary: Nutricost’s 250mg TUDCA offers the best value and effectiveness in its category. Backed by quality assurance and thousands of positive reviews, it’s a top-tier option for liver and bile health.
2. Best Dual-Function Bile Salt Formula: Double Wood TUDCA 250mg (60 Capsules)
Price: $24.95
Double Wood Supplements delivers a potent TUDCA formula with 500 mg per serving, crafted for those who want maximum liver and gallbladder support in fewer capsules. Made in the USA with third-party testing and globally sourced ingredients, it’s a popular pick among experienced supplement users.
Key Benefits
- Helps lower liver enzymes and promote bile flow
- Supports gallbladder and digestion
- Aids recovery from fatty liver, inflammation, and medication-related stress
- Promotes gut and thyroid function
- May reduce discomfort and pain related to sluggish liver function
Key Ingredients
- TUDCA (Tauroursodeoxycholic Acid): 500 mg per 2-capsule serving
- Form: Capsule
- Serving Size: 2 capsules daily (empty stomach recommended)
- Other ingredients: Gelatin, rice flour, vegetable stearate, silica
Pros
- High potency—500 mg per serving
- Manufactured in GMP-certified, U.S.-based facility
- Third-party tested for safety and purity
- Highly rated for fast, noticeable effects
- Great option for those needing higher doses
Cons
- Capsule contains gelatin (not vegan-friendly)
- Must take 2 capsules daily (only 30 servings per bottle)
- Some report bitter taste or mild stomach discomfort if not taken correctly
Customer Feedback
- Effectiveness: Overwhelmingly praised for quick results—some feel better in just 2 days. Users report improvements in energy, digestion, and liver test results.
- Liver Health: Trusted by those with mild liver issues, post-medication recovery, or high liver enzymes. Many report normalized labs and better bile flow.
- Ease of Use: Small capsules, easy to swallow. Works best when taken on an empty stomach.
- Value for Money: Most believe it’s fairly priced for the quality and strength, though a few mention it’s more expensive than alternatives.
- Quality: Users highlight consistency, purity, and authentic “bitter” taste as signs of real, effective TUDCA.
Best Suited For
People needing stronger liver and gallbladder support, including those recovering from medications, fatty liver, or high inflammation. Ideal for those seeking higher potency or stacking for biohacking.
Usage Recommendations
Take 2 capsules daily on an empty stomach. Drink water afterward. Start with 1 capsule if sensitive, and increase gradually. Can be paired with NAC or milk thistle for synergistic effects.
Summary: With a full 500 mg dose of TUDCA per serving, Double Wood’s formula is one of the most effective options for liver, gallbladder, and inflammation support. It’s trusted for its purity, potency, and fast results.
3. Best Clinically Dosed & Vegan-Friendly TUDCA: Force Factor TUDCA 250mg (60 Vegetable Capsules)
Price: $34.99
Force Factor’s TUDCA supplement delivers 250mg of tauroursodeoxycholic acid per capsule—a clinically supported dose designed to promote both liver and digestive health. Made in the USA with a vegan-friendly formula, this product targets adults seeking natural liver detox support, particularly those exposed to medications, alcohol, or poor diet.
Key Benefits
- Supports liver cell regeneration and detoxification
- Aids in healthy bile flow to protect gallbladder and liver
- Helps reduce gastrointestinal discomfort and acid reflux
- Vegan, gelatin-free, non-GMO, and sugar-free
- Clinically dosed at 500mg/day (2 capsules) for best effect
Key Ingredients
- TUDCA (Tauroursodeoxycholic Acid) – 250 mg per capsule (500 mg/day when taken twice daily)
- Other ingredients: Microcrystalline cellulose, hypromellose (capsule), vegetable magnesium stearate, silicon dioxide
Pros
- Clinically backed 500 mg daily dose
- Free from gelatin, sugar, preservatives, and artificial additives
- Easy-to-swallow, slender vegan capsules
- Made in the USA in GMP-certified facilities
Cons
- Slightly bitter taste noted by some users
- No third-party testing certification
- Some users did not notice immediate or measurable benefits
Customer Feedback
- Value for Money: Most users feel the quality justifies the price, especially given the clean ingredient list and clinical dosing.
- Effectiveness: Many customers with fatty liver, high medication use, or casual alcohol intake reported feeling better, including improved liver values or digestion.
- Ease of Use: Capsules are described as slender, tasteless, and easy to swallow—even without food.
- Side Effects: No major side effects were reported; a few noticed mild bitterness but no stomach issues.
- Overall Satisfaction: Customers appreciate the formula’s purity, US manufacturing, and liver support—though some desire third-party lab testing for added assurance.
Best Suited For
- Adults with fatty liver, gallbladder issues, or sluggish digestion
- Individuals on regular pain or statin medications
- Those who drink socially and want liver support
- Health-conscious users looking for clean-label detox aids
Usage Recommendations
Take 1 capsule twice daily (ideally with meals) for a total of 500 mg per day. Users recommend consistent daily use for at least 3–4 weeks to see results. Pairing with healthy diet choices (less alcohol, fats) can enhance benefits.
Summary: Force Factor TUDCA offers potent liver and bile support in a clean, vegan capsule. Backed by clinical dosing and praised for ease of use, it’s ideal for anyone seeking liver and digestive support—especially when exposed to stressors like alcohol, pain meds, or processed foods.
4. Best TUDCA for Full Body Detox: Nature’s Craft TUDCA 500mg (60 Capsules)
Price: $28.99
Nature’s Craft TUDCA delivers a high-potency formula with 500mg per serving of tauroursodeoxycholic acid (TUDCA), designed for liver, gallbladder, kidney, and digestive health. This product is marketed as a detox and bile salt support supplement and comes in a 60-capsule bottle, offering a 30-day supply.
Key Benefits
- Supports liver function and bile flow
- Aids kidney and gallbladder health
- Helps with digestive comfort and gut balance
- May support clarity, energy, and overall well-being
- Contributes to gentle detoxification
Main Ingredients
- Tauroursodeoxycholic Acid (TUDCA) – 500mg per 2-capsule serving
- Capsule and filler ingredients include: rice flour, microcrystalline cellulose, silica, and vegetable cellulose
Pros
- Strong 500mg daily dose backed by clinical use
- Free from gluten, gelatin, and common allergens
- Manufactured in GMP-certified and ISO-tested facilities
- Positive feedback on gut relief and ease of swallowing
- Reported benefits for clarity, energy, and bloating relief
Cons
- Slight bitterness noted by some users
- Lacks third-party certification for purity
- Some customers uncertain about noticeable effects
Customer Feedback:
- Gut Health: Many users felt their digestion improved, with mentions of reduced bloating and stomach discomfort. Some also reported strengthened gut health and liver function.
- Quality: Most reviewers praised its effectiveness and trusted the brand. A few mentioned it “seems OK” but needs more time for clear results.
- Ease of Swallowing: Capsules are small, smooth, and tasteless or mildly bitter, making them easy to take.
- Side Effects: No negative effects were reported; some users felt more energetic and “clean” internally.
- Size: The capsule size was consistently described as convenient and comfortable to swallow.
- Cleansing Effect: Multiple reviews mentioned a gentle detoxifying effect, with some describing an “instant cleanse” feeling.
- Focus and Well-being: A handful of users noted improved mental sharpness and a greater sense of energy and focus.
- Taste: Mixed feedback—some found no taste, others noticed slight bitterness, but no lingering aftertaste.
Best Suited For
Adults looking for a liver detox solution that also supports kidney, gallbladder, and gut health—especially those needing bile flow support or seeking relief from digestive discomfort.
Usage Recommendations
Take 2 capsules daily, preferably with meals. Best results may be seen with consistent use alongside a healthy lifestyle.
Summary: Nature’s Craft TUDCA delivers a potent 500mg dose with a clean ingredient profile for liver, gallbladder, and gut support. Its ease of swallowing, digestive relief, and mild detox effects make it a solid choice, especially for users seeking broader organ support.
5. Best High-Dose + Herbal Combo: Vinatura TUDCA with Milk Thistle 1250mg (90 Capsules)
Price: $26.89
VINATURA TUDCA with Milk Thistle is a dual-action liver support supplement made in the USA. Each serving delivers 1,000mg of TUDCA along with 250mg of standardized Milk Thistle extract, offering potent detox support for liver, gallbladder, and digestive health. This formula targets adults looking for strong antioxidant protection and bile flow enhancement.
Key Benefits
- Promotes healthy bile flow and liver detoxification
- Supports liver enzyme function and gut balance
- Helps reduce bloating and improve digestion
- Combines TUDCA and high-strength silymarin for enhanced antioxidant protection
- Manufactured in the USA and 3rd-party tested
Key Ingredients
- TUDCA (Tauroursodeoxycholic acid) – 1,000 mg
- Milk Thistle Extract – 250 mg (80% silymarin flavonoids, 30% silybin & isosilybin)
- Form: Capsule (90 per bottle, 45 servings)
- Suggested Use: 2 capsules per day
Pros
- High potency 1250mg per serving
- Includes premium Milk Thistle for added liver protection
- Gluten-free, dairy-free, soy-free, preservative-free
- Made in a cGMP-certified facility and 3rd-party tested
Cons
- May be too strong for beginners new to TUDCA
- Slightly bitter aftertaste noted by some users
Customer Feedback:
- Effectiveness: Customers frequently highlight improved liver enzyme levels, reduced bloating, and better bowel regularity. One noted it “works better than just an ox bile.”
- Digestion: Many users report better digestion and reduced post-meal bloating, with no stomach upset.
- Ease of Use: Users find the capsules easy to swallow with no unpleasant aftertaste for most.
- Side Effects: No major side effects were reported; most users tolerate the supplement well.
- Taste: Mixed feedback — some say it’s tasteless, others notice a slight bitterness.
Best Suited For
Adults looking for a high-dose TUDCA formula with added antioxidant support from Milk Thistle — especially useful for those with liver burden from medications, alcohol, or poor bile production.
Usage Recommendations
Take 2 capsules daily with water, preferably with meals. For optimal results, avoid alcohol and maintain consistent daily use.
Summary: VINATURA TUDCA with Milk Thistle delivers one of the strongest clinical doses on the market with added antioxidant support. Ideal for advanced liver and digestive health support, especially for those seeking detox, bile flow, and oxidative protection in one.
6. Best TUDCA + Ox Bile Support: NatureBell TUDCA 500mg with Ox Bile 125mg (120 Capsules)
Price: $19.99
NatureBell’s TUDCA 500mg with Ox Bile 125mg is a dual-acting bile salt supplement designed to support liver detox, digestion, and bile flow. This 2-in-1 formula includes Livamate™, aiming for superior bioavailability and enhanced results. It is particularly suitable for those seeking advanced liver and digestive support in one formula.
Key Benefits
- Promotes liver detox and cleansing
- Supports gallbladder and bile duct health
- Enhances digestion, especially of fats and proteins
- May improve nutrient absorption and liver enzyme balance
- Helps maintain healthy sleep and energy levels
Key Ingredients
- TUDCA (Tauroursodeoxycholic Acid): 500 mg per serving
- Ox Bile: 125 mg per serving
- Other Ingredients: Silicon dioxide, rice flour, gelatin capsule
Each serving consists of 3 capsules, with a 40-day supply per bottle (120 capsules total).
Pros
- Contains both TUDCA and Ox Bile for dual-function support
- Enhanced absorption via Livamate™ formula
- Reported benefits for liver detox, digestion, and keto dieters
- No major allergens (free of gluten, soy, dairy, fish, peanuts)
- 3rd-party tested in the USA
Cons
- Requires 3 capsules per serving
- Contains gelatin (not vegan-friendly)
- Some users wished it included Milk Thistle
Customer Feedback
- Health Benefits: Customers consistently report noticeable improvements in liver function, fat digestion, and energy levels. Several mention its usefulness on a keto diet or for those without a gallbladder.
- Quality: Described as a premium product with pure ingredients and reliable quality, with many praising its value.
- Functionality: Some users note rapid improvement in liver symptoms, digestion, and pressure-related discomfort.
- Value for Money: Most customers consider it a great deal for the potency and effectiveness offered.
- Digestion: Users say it’s easy to swallow and helpful in reducing bloating and aiding digestion.
- Sleep Quality: A few mentioned better sleep and energy balance after use.
Best Suited For
- Individuals on a keto or high-fat diet
- People with gallbladder issues or post-gallbladder surgery
- Those needing support for liver enzyme balance and detox
- Users looking for high-absorption bile salt combinations
Usage Recommendations
Take 3 capsules daily with food for optimal absorption and digestive support. Best taken with a fatty meal to enhance bile flow and minimize any potential discomfort.
Summary: NatureBell’s TUDCA with Ox Bile offers a potent and well-absorbed formula for liver detox, digestion, and gallbladder support. With its dual-action ingredients and high customer satisfaction, it’s an excellent choice for comprehensive bile salt supplementation.
7. Best Entry-Level High-Potency TUDCA: Primaforce TUDCA 500mg (30 Capsules)
Price: $24.50
Primaforce TUDCA delivers a clean, straightforward formula with 500 mg of pure TUDCA per capsule. Manufactured in an NSF-certified, GMP-compliant facility, it is ideal for those looking for a no-frills, high-potency liver supplement. Each bottle contains 30 servings.
Key Benefits
- Promotes liver detoxification and bile flow
- Supports digestive health and gut integrity
- May assist with liver enzyme balance in heavy users (e.g., alcohol, medications)
- Easy to add to daily wellness or fitness routines
Key Ingredients
- TUDCA (Tauroursodeoxycholic Acid) – 500 mg per capsule
- No additional active ingredients or herbal blends
Pros
- Pure and focused TUDCA formula, no proprietary blends
- Third-party tested for quality and potency
- NSF-certified manufacturing process
- Small, easy-to-swallow capsules
- Clear dosing: 1 capsule = 500 mg
Cons
- Only 30 capsules per bottle (may require repurchase sooner)
- No added bile salts or synergistic ingredients like milk thistle
- Some users reported mild digestive upset
Customer Feedback
Value for Money:
Users note the product offers good value for its clean formula and effective dosage. However, with only 30 capsules per bottle, it’s more expensive per serving compared to others.
Effectiveness:
Many customers appreciate its potent liver support and overall clean-label promise. It is often used by those needing liver protection (e.g., heavy drinkers, athletes on cycles).
Ease of Use:
Capsules are described as easy to swallow and with no aftertaste. The simplicity of the formula is a highlight.
Side Effects:
A few users mentioned mild stomach upset, but these instances were limited. One user reported no noticeable difference.
Overall Satisfaction:
Customers feel reassured by the transparency and single-ingredient formula. Especially praised for being free of blends and additives, making it ideal for purists.
Highlighted Ingredients
- TUDCA (500 mg) per serving – bile acid derivative known to support bile flow, liver enzyme balance, and cellular protection.
Best Suited For
- Individuals who want a pure, high-potency TUDCA without extra herbs or additives.
- Those with sensitive systems avoiding soy, dairy, gluten, or filler blends.
- Athletes or users cycling on high-stress supplements needing liver support.
Usage Recommendations
- Take 1 capsule per day, preferably with food.
- Avoid combining with alcohol or bile acid absorption inhibitors.
Summary: Primaforce TUDCA is ideal for those who want a clean, potent supplement focused solely on TUDCA. With 500 mg per serving and third-party testing, it’s a great choice for liver detox without extras.
What Is TUDCA?
TUDCA (tauroursodeoxycholic acid) is a water-soluble bile acid that naturally occurs in the human body in small amounts. It plays a vital role in bile flow and liver detoxification.
While it’s been used for decades in Europe and Asia as a prescription treatment for liver and gallbladder diseases, it’s now widely available as a dietary supplement in the U.S.
TUDCA helps break down fats, prevent bile acid buildup, and protect liver cells from damage due to oxidative stress and inflammation.
Benefits of TUDCA Supplements
Studies and anecdotal evidence suggest TUDCA may offer a wide range of health benefits, especially for liver, gut, and cellular health:
- Supports Liver Detoxification: Helps reduce liver enzymes and protect liver cells from damage caused by toxins or fatty buildup.
- Improves Bile Flow: Assists with bile circulation, aiding digestion and the breakdown of dietary fats.
- Protects Mitochondria and Brain Cells: Early studies show promise in protecting neurological function and reducing inflammation.
- Supports Insulin Sensitivity: May aid metabolic function and reduce risk factors for insulin resistance.
- Promotes Gut and Gallbladder Health: Helps prevent gallstones and supports healthy bile acids in the intestines.
How We Chose the Best TUDCA Supplements
Our selection process focused on:
- Dosage per Serving: We prioritized products offering a clinical dose of TUDCA, ideally 250–1,000 mg per day.
- Purity and Formulation: Looked for pure TUDCA supplements with minimal additives, ideally free of unnecessary fillers or allergens.
- Third-Party Testing: Products with certificates of analysis or independent lab testing earned extra points.
- Customer Feedback: We analyzed verified reviews to assess real-world effectiveness, side effects, and satisfaction.
- Brand Transparency: Companies with clear labeling, good customer support, and a strong reputation were favored.
Potential Side Effects of TUDCA
TUDCA is generally well tolerated, even at higher doses, but a few mild side effects may occur:
- Nausea or bloating
- Mild stomach discomfort
- Possible loose stools at high doses
It’s important to consult a healthcare provider if you’re pregnant, nursing, or taking medications, especially those that affect the liver or bile production.
Who Should Consider Taking TUDCA?
TUDCA is ideal for a variety of individuals, including:
- Those with non-alcoholic fatty liver disease (NAFLD)
- People on high-protein or high-fat diets
- Athletes or bodybuilders using performance-enhancing substances that may strain the liver
- Individuals with slow digestion or gallbladder issues
- Biohackers and longevity enthusiasts looking to optimize liver and mitochondrial health
How to Take TUDCA Supplements
Most clinical studies use doses between 250 mg and 1,500 mg daily.
Here’s how to get the most from your TUDCA supplement:
- Start with 250–500 mg/day and gradually increase if needed.
- Take with food to minimize stomach upset.
- Consider stacking with NAC, milk thistle, or alpha-lipoic acid for enhanced liver support.
FAQ – Frequently Asked Questions
Is TUDCA safe for long-term use?
Yes, most research and anecdotal use suggest it’s safe for long-term supplementation when used at proper doses.
How long does it take to see results?
Some users notice improved digestion and energy in a few days, while liver enzyme improvements may take 2–4 weeks.
Can I stack TUDCA with other liver supplements?
Absolutely. It pairs well with NAC, milk thistle, glutathione, and other detox-supporting nutrients.
Does TUDCA require a prescription?
No, in the U.S., TUDCA is sold as an over-the-counter dietary supplement.
Is TUDCA only for people with liver problems?
Not at all. Many people use it proactively for liver protection, detox, and metabolic health.
Final Verdict
TUDCA has quickly earned a spot among the most effective supplements for liver, bile, and metabolic health. Backed by research and praised by thousands of users, it’s an excellent choice whether you’re addressing liver concerns or optimizing your overall wellness.