Best 5 Vitamin B3 Supplements for Energy, Skin & NAD Support

Vitamin B3, also known as niacin, is an essential nutrient that supports energy production, metabolism, skin health, and cardiovascular function. While many people obtain vitamin B3 from foods such as meat, fish, and whole grains, supplementation can be beneficial for those with higher nutritional needs or specific health goals.

In this guide, we’ll explain what vitamin B3 is, its main benefits, the different forms available, who may benefit from supplementation, and how to choose the best vitamin B3 supplement.

Our Top Picks for Vitamin B3 Supplements

1. Best Overall Vitamin B3 Supplement: Nutricost Niacinamide (Vitamin B3) 500 mg (240 Capsules)

• Why? Uses a clean, flush-free niacinamide formula with a well-balanced 500 mg dose per capsule, offering excellent value for long-term daily use. Third-party tested and free from unnecessary additives.
• Key Benefits: Supports energy production, skin health, nervous system function, and overall cellular metabolism without causing niacin flush.
• Best for: Most users looking for a reliable, affordable, and well-rounded vitamin B3 supplement for daily use.

2. Best for NAD & Longevity Support: aSquared Nutrition Nicotinamide with Resveratrol 500 mg (120 Veggie Capsules)

• Why? Combines high-dose nicotinamide with added resveratrol to support NAD levels, cellular health, and longevity pathways. Flush-free, vegan-friendly, and third-party tested.
• Key Benefits: Supports NAD/NAD+ production, cellular repair, antioxidant protection, energy levels, and healthy aging.
• Best for: Users focused on anti-aging, longevity, and enhanced cellular health beyond basic vitamin B3 support.

3. Best High-Dose & Best Value Bulk Option: DEAL SUPPLEMENT Nicotinamide 1,000 mg (500 Capsules)

• Why? Delivers one of the highest nicotinamide dosages available at an extremely low cost per capsule, making it ideal for long-term, high-dose supplementation.
• Key Benefits: Supports energy metabolism, skin health, cellular regeneration, and vitamin B3 sufficiency without flushing.
• Best for: Experienced users or those under professional guidance who want a high-potency, budget-friendly vitamin B3 supplement.

4. Best Daily NAD+ Support (Moderate Dose): Nature’s Craft Nicotinamide (Vitamin B3) 500 mg (60 Capsules)

• Why? Provides a straightforward, once-daily 500 mg nicotinamide dose with a focus on NAD+ support, skin health, and mitochondrial energy. Vegan, non-GMO, and lab tested.
• Key Benefits: Supports NAD+ levels, energy production, skin barrier function, and cognitive clarity without flushing.
• Best for: Users who prefer a simple, moderate-dose vitamin B3 supplement with an emphasis on daily NAD+ support.

5. Best Bulk Flush-Free Niacin Alternative: Micro Ingredients Niacin (Vitamin B3) 500 mg (400 Capsules)

• Why? Offers a large bulk supply of flush-free niacin at a competitive price, with a clean, allergen-conscious formula designed for consistent daily use.
• Key Benefits: Supports energy metabolism, skin health, NAD/NADP production, and overall wellness.
• Best for: Budget-conscious users who want a long-lasting vitamin B3 supplement and don’t mind taking two capsules per serving.

Rank	Product	Form	Price per Count	Highlight	Key Benefits	Best For
1️⃣	Nutricost Niacinamide (Vitamin B3) 500 mg (240 Capsules)	Capsule	~$0.10 / count	Best Overall Vitamin B3 Supplement	Flush-free niacinamide, supports energy production, skin health, nervous system and cellular metabolism, clean minimalist formula	Most users seeking a balanced, affordable, and reliable vitamin B3 for daily use
2️⃣	aSquared Nutrition Nicotinamide with Resveratrol 500 mg (120 Veggie Capsules)	Veg Capsule	~$0.25 / count	Best for NAD & Longevity Support	Supports NAD/NAD+ levels, cellular repair, antioxidant protection, energy production, flush-free formula	Users focused on anti-aging, longevity, and cellular health beyond basic B3 support
3️⃣	DEAL SUPPLEMENT Nicotinamide 1,000 mg (500 Capsules)	Capsule	~$0.04 / count	Best High-Dose & Best Value Bulk Option	High-potency nicotinamide, supports energy metabolism, skin health, and long-term B3 sufficiency without flushing	Experienced or high-dose users wanting maximum value and long-term supply
4️⃣	Nature’s Craft Nicotinamide (Vitamin B3) 500 mg (60 Capsules)	Capsule	~$0.14 / count	Best Daily NAD+ Support	Supports NAD+ production, mitochondrial energy, skin barrier health, and cognitive clarity, flush-free	Users who prefer a moderate, once-daily B3 supplement with a clean formula
5️⃣	Micro Ingredients Niacin (Vitamin B3) 500 mg (400 Capsules)	Capsule	~$0.06 / count	Best Bulk Flush-Free Niacin Alternative	Supports energy metabolism, NAD/NADP production, skin health, large bulk supply, allergen-friendly formula	Budget-conscious users seeking a long-lasting vitamin B3 supplement for daily use

1. Best Overall Vitamin B3 Supplement: Nutricost Niacinamide (Vitamin B3) 500 mg (240 Capsules)

Price: $14.95

Nutricost Niacinamide is a high-dose vitamin B3 supplement designed for users who want the benefits of niacin without the uncomfortable flushing commonly associated with traditional niacin (nicotinic acid). With 500 mg of niacinamide per capsule and a generous 240-capsule bottle, this product stands out as a strong value-focused option for long-term daily use.

Overview

• Brand: Nutricost
• Form: Capsule
• Vitamin B3 Type: Niacinamide (flush-free)
• Dosage: 500 mg per capsule
• Serving Size: 1 capsule
• Servings per Bottle: 240
• Dietary Features: Non-GMO, gluten-free, soy-free
• Manufacturing: NSF-certified, GMP-compliant, FDA-registered facility

Key Benefits

• Supports skin health and dermatological wellness
• Helps maintain cellular energy metabolism
• Flush-free formula ideal for sensitive users
• May support cholesterol and heart health when used appropriately
• Suitable for daily, long-term supplementation

Why This Formula Stands Out

Nutricost uses niacinamide, a non-flushing form of vitamin B3 that delivers many of the same metabolic and skin benefits as niacin without causing redness, warmth, or tingling. This makes it especially appealing for people who have experienced discomfort with standard niacin products.

At 500 mg per capsule, the dosage is considered high-potency, allowing flexibility for users following dermatologist-recommended or practitioner-guided protocols.

Customer Feedback

Based on a large volume of verified Amazon reviews, customers frequently highlight:

• Quality: Praised for consistent potency and clean formulation
• Value for Money: One of the lowest cost-per-capsule vitamin B3 options available
• Skin Health: Many users report improvements in skin texture and dermatological conditions
• Ease of Swallowing: Capsules are generally described as easy to take
• Effectiveness: Positive feedback for cholesterol and general health support

Some users note mild digestive discomfort or nausea, which is common with higher-dose B vitamins, particularly when taken on an empty stomach.

Pros

• High-dose 500 mg niacinamide per capsule
• Flush-free, well-tolerated by most users
• Large 240-capsule supply for long-term use
• Excellent price-to-quantity ratio
• Clean label with minimal additives

Cons

• High dosage may be unnecessary for beginners
• Not vegan (gelatin capsule)
• No added cofactors (such as other B vitamins)

Best Suited For

• Adults seeking flush-free vitamin B3 support
• Users focused on skin health and daily metabolic support
• Budget-conscious shoppers wanting a long-term supply
• Those who prefer simple, single-ingredient formulas

Usage Recommendations

Most users take 1 capsule daily with food to reduce the risk of stomach discomfort. Due to the high dosage, individuals with medical conditions or those taking prescription medications should consult a healthcare professional before use.

Bottom Line: Nutricost Niacinamide 500mg is a reliable, high-value vitamin B3 supplement that delivers a strong dose in a flush-free form. Its clean formulation, excellent pricing, and overwhelmingly positive customer feedback make it a solid contender for anyone looking to add vitamin B3 to their daily wellness routine—especially for skin and metabolic support.

2. Best for NAD & Longevity Support: aSquared Nutrition Nicotinamide with Resveratrol 500 mg (120 Veggie Capsules)

Price: $29.95

aSquared Nutrition Nicotinamide with Resveratrol is a premium vitamin B3 formula designed for users who want more than basic niacinamide. By combining a high-dose, flush-free nicotinamide with resveratrol, this supplement targets NAD support, cellular health, energy levels, and healthy aging, making it a more advanced option compared to standalone vitamin B3 products.

Overview

• Brand: aSquared Nutrition
• Form: Vegetable capsules
• Vitamin B3 Type: Nicotinamide (niacinamide, non-flush)
• Dosage per Capsule:
  • Nicotinamide (Vitamin B3): 500 mg
  • Resveratrol (Polygonum cuspidatum root, 7% yield): 100 mg
• Servings per Bottle: 120
• Dietary Features: Vegan, Non-GMO, gluten-free
• Manufacturing: USA formulated, third-party tested

Key Benefits

• Supports NAD / NAD+ levels and cellular energy production
• Combines vitamin B3 with resveratrol for longevity support
• Flush-free formula suitable for sensitive users
• Supports skin cell health and overall wellness
• Provides antioxidant support for healthy aging

What Makes This Formula Different

Unlike basic niacinamide supplements, this product adds resveratrol, a well-known polyphenol studied for its role in cellular protection and longevity pathways. The combination is often favored by users interested in anti-aging, mitochondrial health, and long-term metabolic support, without stepping into higher-cost NAD boosters like NR or NMN.

The use of vegetable capsules and a vegan-friendly formulation also makes it appealing to plant-based users who want a clean, modern supplement stack.

Customer Feedback

From verified Amazon reviews, customers commonly mention:

• Skin Health: Many users report gradual but noticeable improvements in skin appearance and skin-related concerns
• Energy Levels: Frequently described as increased energy without jitters or stimulants
• Quality: Strong trust in ingredient quality and formulation
• Ease of Swallowing: Veggie capsules are generally easy to take
• Resveratrol Content: Mixed feedback, with some users appreciating the combination and others noting it is not NR or NMN

Some users report mild side effects such as stomach discomfort or headaches, particularly when taken on an empty stomach or combined with other supplements.

Pros

• High-dose 500 mg flush-free nicotinamide
• Added 100 mg resveratrol for antioxidant and longevity support
• Vegan-friendly vegetable capsules
• Third-party tested and Non-GMO
• Suitable for users focused on NAD and healthy aging

Cons

• Significantly more expensive per capsule than basic B3 supplements
• Resveratrol dose is moderate and may not satisfy high-dose users
• Not ideal for beginners looking for simple, low-cost vitamin B3

Best Suited For

• Adults focused on healthy aging and longevity support
• Users interested in NAD-related pathways without using NR or NMN
• Those wanting a flush-free vitamin B3 with added antioxidants
• Vegan users seeking a clean, multi-benefit formula

Usage Recommendations

Most users take 1 capsule daily with food. Because this formula contains both nicotinamide and resveratrol, it may be best taken earlier in the day. Individuals taking medications or stacking with other longevity supplements should consult a healthcare professional.

Bottom Line: aSquared Nutrition Nicotinamide with Resveratrol is a step-up vitamin B3 supplement designed for users who want more than basic niacinamide. While it costs more than standard B3 options, the added resveratrol, vegan-friendly formulation, and focus on cellular and NAD support make it a strong choice for those prioritizing long-term wellness and healthy aging over budget pricing.

3. Best High-Dose & Best Value Bulk Option: DEAL SUPPLEMENT Nicotinamide 1,000 mg (500 Capsules)

Price: $21.95

DEAL SUPPLEMENT Nicotinamide is an extra-strength, high-count vitamin B3 supplement built for users who want maximum dosage and long-term value. With 1,000 mg of flush-free nicotinamide per serving and a massive 500-capsule bottle, this product is positioned as a budget powerhouse for sustained daily supplementation.

Overview

• Brand: DEAL SUPPLEMENT
• Form: Capsules
• Vitamin B3 Type: Nicotinamide (niacinamide, non-flush)
• Dosage per Serving: 1,000 mg (500 mg per capsule, 2 capsules per serving)
• Servings per Bottle: 250
• Dietary Features: Non-GMO, gluten-free, allergen-free
• Quality Standards: Third-party lab tested, cGMP compliant

Key Benefits

• Provides high-potency vitamin B3 for daily metabolic support
• Flush-free formula avoids redness, itching, and discomfort
• Supports skin health, cellular energy production, and metabolism
• Long-term supply ideal for consistent, routine use
• Clean formula suitable for users with common food sensitivities

What Makes This Formula Stand Out

This product is designed for users who prioritize dose and quantity over added extras. Instead of blending vitamin B3 with other compounds, DEAL SUPPLEMENT focuses on delivering pure nicotinamide in a water-soluble, bioavailable form.

With 500 capsules per bottle, it offers one of the lowest cost-per-capsule options in the vitamin B3 category, making it especially appealing for long-term users or households that supplement daily.

Customer Feedback

From verified Amazon reviews, customers frequently mention:

• Quality: Consistently described as high quality and reliable
• Health Benefits: Users report support for cellular health, metabolism, and overall wellness
• Ease of Swallowing: Capsules are generally considered easy to take
• Value for Money: Strong appreciation for the large bottle size and pricing
• Flush Response: Most users experience no flushing, though a small number report mixed reactions

A few users note mild side effects such as headaches or stomach discomfort, which is not uncommon with high-dose B-vitamin supplementation, particularly when taken without food.

Pros

• Very high 1,000 mg per serving (extra-strength)
• Massive 500-capsule bottle (up to 250-day supply)
• Flush-free nicotinamide form
• Excellent price per capsule
• Free from common allergens and additives

Cons

• Requires taking 2 capsules per serving
• Not vegan (gelatin capsules)
• No added cofactors (resveratrol, NR, NMN, or other B vitamins)

Best Suited For

• Users wanting high-dose vitamin B3 supplementation
• Budget-conscious shoppers seeking maximum long-term value
• Adults focused on skin health, metabolism, and energy support
• Those who prefer simple, single-ingredient formulas

Usage Recommendations

Adults typically take 2 capsules daily with food. Because this is a high-dose formula, users new to vitamin B3 may consider starting with 1 capsule daily to assess tolerance before increasing.

Individuals taking medications or managing medical conditions should consult a healthcare professional before using high-dose vitamin B3 supplements.

Bottom Line: DEAL SUPPLEMENT Nicotinamide 1,000 mg is a high-potency, no-frills vitamin B3 supplement that delivers exceptional value. While it lacks added longevity or antioxidant ingredients, its clean formulation, flush-free profile, and extremely low cost per capsule make it an excellent choice for users who want maximum vitamin B3 intake at minimal cost.

4. Best Daily NAD+ Support (Moderate Dose): Nature’s Craft Nicotinamide (Vitamin B3) 500 mg (60 Capsules)

Price: $9.99

Nature’s Craft Nicotinamide is a clean, mid-potency vitamin B3 supplement formulated for users who want daily NAD+ support, skin health benefits, and mitochondrial energy without committing to very high doses or large bottles. With 500 mg of flush-free nicotinamide per capsule, it’s positioned as a balanced, once-daily option backed by strong customer satisfaction.

Overview

• Brand: Nature’s Craft
• Form: Capsules
• Vitamin B3 Type: Nicotinamide (niacinamide, non-flush)
• Dosage per Capsule: 500 mg
• Servings per Bottle: 60
• Dietary Features: Vegan, non-GMO, gelatin-free
• Manufacturing: GMP-compliant, lab tested, USA sourced ingredients

Key Benefits

• Supports NAD+ production and mitochondrial energy
• Helps promote healthy skin barrier and skin cell renewal
• Flush-free vitamin B3 suitable for sensitive users
• Supports brain function, focus, and mental clarity
• Once-daily dosing for simple supplementation

What Makes This Formula Stand Out

Nature’s Craft positions this product clearly as an NAD+ precursor rather than just a basic vitamin B3 capsule. While it does not include added compounds like resveratrol or NR, it appeals to users who want a straightforward, clinically familiar form of vitamin B3 with consistent daily dosing.

The 500 mg per capsule dosage hits a sweet spot for users who want noticeable benefits without stepping into ultra-high-dose territory.

Customer Feedback

Based on verified Amazon reviews, customers frequently mention:

• Skin Health: Many report improvements in skin appearance and protection, including dermatologist-recommended use
• Energy Levels: Users note steady energy and reduced afternoon fatigue
• Quality: Strong trust in ingredient quality and consistency
• Flushing: Majority confirm no flushing or redness
• Ease of Swallowing: Capsules are generally easy to take

Taste feedback is mixed, though most users report no noticeable aftertaste.

Pros

• Balanced 500 mg flush-free nicotinamide dose
• Vegan and gelatin-free capsules
• Strong focus on NAD+ and mitochondrial health
• High customer satisfaction with minimal side effects
• Simple once-daily capsule

Cons

• Smaller bottle compared to bulk options
• Higher cost per capsule than budget brands
• No added longevity cofactors (resveratrol, NMN, NR)

Best Suited For

• Users seeking daily NAD+ and energy support
• Adults focused on skin health and cellular renewal
• Those who prefer moderate dosing over mega-dose formulas
• Vegan users wanting a clean, plant-based capsule

Usage Recommendations

Take 1 capsule daily with a meal, preferably earlier in the day. Users stacking with other NAD-focused supplements should avoid overlapping high doses unless advised by a healthcare professional.

Bottom Line: Nature’s Craft Nicotinamide 500 mg is a well-rounded, flush-free vitamin B3 supplement ideal for users who want consistent NAD+ support, skin benefits, and energy without excessive dosing. While it’s not the cheapest or most advanced formula, its clean profile, vegan capsules, and strong user feedback make it a dependable daily wellness option.

5. Best Bulk Flush-Free Niacin Alternative: Micro Ingredients Niacin (Vitamin B3) 500 mg (400 Capsules)

Price: $16.99

Micro Ingredients Niacin 500 mg is a bulk-size, value-driven vitamin B3 supplement designed for users who want flush-free niacin support, strong daily dosing, and a long-lasting supply. With 400 capsules per bottle and a clean, allergen-conscious formula, this product is well suited for consistent, everyday use focused on energy metabolism, skin health, and overall wellness.

Overview

• Brand: Micro Ingredients
• Form: Capsules
• Vitamin B3 Type: Niacin (flush-free formulation)
• Dosage per Serving: 500 mg (2 capsules)
• Servings per Bottle: 200
• Dietary Features: Non-GMO, gluten-free, soy-free, dairy-free, nut-free
• Quality Standards: Third-party lab tested

Key Benefits

• Supports energy production via NAD and NADP pathways
• Flush-free formula designed to avoid redness and tingling
• Helps maintain skin health and complexion
• Bulk bottle ideal for long-term supplementation
• Clean ingredient profile suitable for sensitive users

What Makes This Formula Stand Out

Micro Ingredients is known for offering minimalist, bulk supplements, and this niacin product follows that philosophy closely. Rather than adding extra compounds, it focuses on delivering double-strength vitamin B3 in a flush-free format at a competitive cost per serving.

With 400 capsules per bottle, it provides one of the largest supplies among vitamin B3 supplements, making it especially attractive for households or individuals supplementing daily.

Customer Feedback

From verified Amazon reviews, customers frequently highlight:

• Value for Money: Strong appreciation for the large bottle and affordable pricing
• Energy Levels: Users report improved daily energy and reduced sluggishness
• Skin Health: Some note clearer complexion and skin protection benefits
• Ease of Swallowing: Capsules are generally easy to take with no bitter taste
• Flushing: Many users experience no flushing, though a small number report mixed sensitivity

A few reviews mention concerns about capsule fill consistency or mild sensitivity, which appears to vary by individual tolerance.

Pros

• Large 400-capsule bulk supply
• Double-strength 500 mg niacin per serving
• Flush-free formulation for most users
• Free from major allergens
• Excellent long-term cost efficiency

Cons

• Requires 2 capsules per serving
• Not vegan (gelatin capsules)
• Mixed feedback on flush-free consistency for very sensitive users

Best Suited For

• Users seeking a bulk vitamin B3 supplement
• Budget-conscious shoppers wanting long-term value
• Adults focused on energy metabolism and skin support
• Those who prefer simple, no-additive formulas

Usage Recommendations

Take 2 capsules daily with food, preferably earlier in the day. New users may wish to start with 1 capsule daily to assess tolerance, especially if sensitive to niacin-related effects.

Bottom Line: Micro Ingredients Niacin 500 mg is a solid, value-oriented vitamin B3 supplement that delivers dependable daily support for energy and skin health in a flush-free format. While it may not be the most refined or specialized option, its large bottle size, clean ingredient list, and competitive pricing make it a strong choice for users prioritizing quantity, simplicity, and affordability.

What Is Vitamin B3?

Vitamin B3, commonly referred to as niacin, is a water-soluble B vitamin that plays a critical role in converting food into energy. It also supports DNA repair, nervous system function, and healthy skin.

Because vitamin B3 is water-soluble, it is not stored in large amounts in the body. Regular intake through diet or supplementation is therefore important for maintaining optimal levels.

Benefits of Vitamin B3 Supplements

Supports Energy Metabolism
Vitamin B3 is essential for the production of NAD and NADP, coenzymes that help cells generate energy from carbohydrates, fats, and proteins.

Supports Cardiovascular Health
Niacin has been studied for its role in supporting healthy cholesterol levels when used appropriately and under medical guidance.

Promotes Skin Health
Niacinamide, a popular form of vitamin B3, is widely used to support the skin barrier, hydration, and overall skin appearance.

Supports Brain and Nervous System Function
Vitamin B3 contributes to normal nervous system function and supports cognitive health through its role in cellular repair and neurotransmitter synthesis.

Supports Digestive Health
Adequate vitamin B3 intake helps maintain healthy digestive function and supports the lining of the gastrointestinal tract.

Types of Vitamin B3 Explained

Niacin (Nicotinic Acid)
This traditional form of vitamin B3 is known for its ability to cause a temporary flushing sensation at higher doses. It is often used for cholesterol-related support.

Niacinamide (Nicotinamide)
A non-flushing form of vitamin B3, niacinamide is commonly used for general health, metabolic support, and skin benefits.

Inositol Hexanicotinate
Often labeled as “flush-free niacin,” this form releases niacin slowly and may be preferred by individuals sensitive to flushing.

Nicotinamide Riboside (NR)
A newer form of vitamin B3 that supports NAD levels and is often associated with cellular energy and healthy aging support.

Who Should Consider Taking Vitamin B3 Supplements?

Individuals with Dietary Gaps
People who consume limited animal products or follow restrictive diets may not get enough vitamin B3 from food alone.

Adults Seeking Energy and Metabolic Support
Vitamin B3 plays a central role in metabolism and may help support consistent energy levels.

Those Focused on Skin Health
Niacinamide supplements are commonly used by individuals looking to support skin hydration and barrier function.

People with Increased Nutrient Needs
Stress, aging, and certain lifestyle factors can increase the body’s demand for B vitamins, including vitamin B3.

Potential Side Effects and Safety Considerations

Flushing
Niacin may cause redness, warmth, or tingling of the skin, particularly at higher doses. This effect is generally harmless but can be uncomfortable.

Digestive Discomfort
Some people may experience nausea or stomach upset, especially if vitamin B3 is taken on an empty stomach.

Liver Health
High-dose niacin supplementation should only be done under medical supervision, as excessive intake may affect liver function.

Medication Interactions
Vitamin B3 may interact with cholesterol-lowering medications or blood pressure drugs. Consult a healthcare professional if you are taking prescription medications.

How to Take Vitamin B3 Supplements

Take with Food
Most vitamin B3 supplements are better tolerated when taken with meals.

Start with Lower Doses
Beginning with a lower dose can help minimize side effects and assess tolerance.

Consider a B-Complex Formula
Vitamin B3 works synergistically with other B vitamins, making B-complex supplements a convenient option for balanced intake.

How to Choose the Best Vitamin B3 Supplement

Choose the Right Form
Niacinamide is generally best for daily wellness and skin support, while niacin may be used for specific cholesterol-related goals.

Clear Dosage Labeling
Look for products with transparent dosing and no proprietary blends.

Clean Ingredient Profile
Avoid supplements with unnecessary fillers, artificial colors, or allergens.

Third-Party Testing
Independent testing adds an extra layer of quality assurance.

Brand Reputation
Well-established brands with transparent sourcing and manufacturing practices are usually more reliable.

Frequently Asked Questions About Vitamin B3 Supplements

Final Thoughts

Vitamin B3 is an essential nutrient that supports energy production, skin health, and nervous system function. Choosing the right form and dosage is key to maximizing benefits while minimizing side effects.

Once your health goals are clear, a high-quality vitamin B3 supplement can be an effective addition to a well-balanced wellness routine.

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